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  • Search results for: 'research area epigenetics hypoxia inducible factors'

Search results for: 'research area epigenetics hypoxia inducible factors'

Items 31-40 of 135

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  1. TG101348 (SAR302503)
    A4136 TG101348 (SAR302503)
     2 Citation
    Target: FLT3|JAK|c-RET
    Summary: JAK-2 inhibitor,potent and selective
      ≥26.23 mg/mL
  2. MLN8054
    A4114 MLN8054
    Target: Aurora Kinases
    Summary: Aurora A inhibitor
      insoluble in EtOH; insoluble in H2O; ≥39.05 mg/mL
  3. JNJ-7706621
    A4115 JNJ-7706621
     1 Citation
    Target: Cyclin-Dependent Kinases|Aurora Kinases
    Summary: Potent CDK/Aurora kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥19.7 mg/mL
  4. 5-Azacytidine
    A1907 5-Azacytidine
     6 Citation
    Target: DNA Methyltransferases
    Summary: DNA methyltransferase inhibitor.
      insoluble in EtOH; ≥24.45 mg/mL
  5. Lomeguatrib
    A1912 Lomeguatrib
    Target: O6-methylguanine-DNA-methyl-transferase (MGMT)
    Summary: MGMT inhibitor
      ≥50 mg/mL
  6. Zebularine
    A1915 Zebularine
     1 Citation
    Target: DNA Methyltransferases|Cytidine deaminases
    Summary: DNA methylation inhibitor
      insoluble in EtOH; ≥50.7 mg/mL
  7. AZD1152
    A3214 AZD1152
     1 Citation
    Target: Aurora Kinases
    Summary: Aurora B kinase inhibitor,highly potent and selective
      insoluble in H2O; insoluble in EtOH; ≥5.88 mg/mL
  8. Tubastatin A HCl
    A8547 Tubastatin A HCl
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC6 inhibitor,potent and selective
      insoluble in EtOH; ≥12.34 mg/mL
  9. Panobinostat (LBH589)
    A8178 Panobinostat (LBH589)
     10 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor
      insoluble in H2O; insoluble in EtOH; ≥17.47 mg/mL
  10. Trichostatin A (TSA)
    A8183 Trichostatin A (TSA)
     13 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor
      insoluble in H2O; ≥15.12 mg/mL

Items 31-40 of 135

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  1. Signaling Pathways 131item
  2. Natural Products 2item
  3. Peptides 1 item
  4. Peptides & Proteins 1 item
Reversibility
  1. Reversible 6item
  2. Irreversible 2item
Target
  1. Caspases 2item
  2. Cyclin-Dependent Kinases 1 item
  3. Proteasome 1 item
  4. Histone Deacetylases (HDACs) 17item
  5. Bcl-2 1 item
  6. PI3K 1 item
  7. Raf 1 item
  8. Aurora Kinases 10item
  9. Bcl-xl 1 item
  10. CSF-1R 1 item
  11. EZH2 2item
  12. Bromodomains 1 item
  13. AP-1 2item
  14. MMP 2item
  15. DT-diaphorases 1 item
  16. FLT3 1 item
  17. Factor Xa 3item
  18. LPA Receptors 1 item
  19. PLK 1 item
  20. VEGFR 8item
  21. PDGFR 5item
  22. c-Kit 2item
  23. Bromodomain-containing proteins(BRDs) 1 item
  24. Mcl-1 1 item
  25. Hydrolase 1 item
  26. SGK 1 item
  27. MEK 1 item
  28. DOT1L 1 item
  29. FGFR 3item
  30. Nrf2 1 item
  31. Insulin-like growth factor receptors(IGFRs) 1 item
  32. Pim 2item
  33. Sir2-like Family Deacetylases (Sirtuins) 3item
  34. Deubiquitinating enzymes (DUBs) 1 item
  35. PP1 1 item
  36. PP2A 1 item
  37. Smoothened 1 item
  38. MET 1 item
  39. Src 1 item
  40. Trk Receptors 1 item
  41. STAT 2item
  42. EGFR 5item
  43. RIP kinases 1 item
  44. Hypoxia Inducible Factors (HIFs) 1 item
  45. JAK 4item
  46. DNA-PK 1 item
  47. HSP90 1 item
  48. Topoisomerases 1 item
  49. ErbB 2item
  50. Ferroptosis 1 item
  51. Toll-like receptors (TLRs) 1 item
  52. Actin 1 item
  53. DNA Methyltransferases 3item
  54. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  55. ERK 1 item
  56. CREBBP 2item
  57. EP300 2item
  58. Lyn 1 item
  59. HER2 1 item
  60. Insulin and Insulin-like Receptors 2item
  61. PARP 1 item
  62. CB1 Receptors 1 item
  63. Dehydrogenase 1 item
  64. Pancreatic and duodenal homeobox 1 (PDX1) 1 item
  65. Fatty-acid-binding proteins (FABPs) 1 item
  66. Free Fatty Acid Receptors 1 item
  67. phosphatases 1 item
  68. Autophagy 2item
  69. C5a receptors 1 item
  70. Farnesyl Diphosphate Synthases 1 item
  71. G9a 1 item
  72. MAGL 1 item
  73. TRP Channel 2item
  74. Apoptosis Inducers 1 item
  75. NO Donors / Precursors 2item
  76. CB2 Receptors 1 item
  77. IL Receptors 1 item
  78. 15-lipoxygenases 1 item
  79. Arp2/3 complex 1 item
  80. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  81. Cytidine deaminases 1 item
  82. PP4 1 item
  83. c-RET 1 item
  84. c-Fms tyrosine kinase 1 item
  85. Elastases 1 item
  86. P97 ATPase 1 item
  87. Histone Acetyltransferases (HATs) 1 item
  88. Lck 1 item
  89. Sirtuin 1 item
Reported Experiments
  1. Animal Experiments 114item
  2. Cell Experiments 73item
Related Disease
  1. Acute Lung Injury 1 item
  2. Acute Myeloid Leukemia 8item
  3. Adrenocortical Carcinoma 1 item
  4. Bladder Cancer 4item
  5. Bladder Carcinoma 1 item
  6. Breast Cancer 29item
  7. Cancer 87item
  8. Cervical Cancer 2item
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  11. Colon Cancer 12item
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  13. Colorectal Cancer 10item
  14. Diabetes 2item
  15. Glioblastoma 8item
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  21. Leukemia 3item
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  23. Lung Cancer 9item
  24. Lung Carcinoma 1 item
  25. Lymphoma 6item
  26. Melanoma 5item
  27. Mixed Lineage Leukemia 1 item
  28. Multiple Myeloma 8item
  29. Myelofibrosis 2item
  30. Myeloma 2item
  31. Neuroblastoma 1 item
  32. Neuronal Protection 1 item
  33. Non-small Cell Lung Cancer 7item
  34. Ovarian Cancer 10item
  35. Pain Relief 1 item
  36. Pancreatic Cancer 11item
  37. Prostate Cancer 18item
  38. Psoriasis 1 item
  39. Pulmonary Arterial Hypertension 1 item
  40. Pulmonary Fibrosis 1 item
  41. Renal Cancer 1 item
  42. Renal Cell Carcinoma 5item
  43. Rheumatoid Arthritis 2item
  44. Sleep Disorders 1 item
  45. Soft Tissue Sarcoma 1 item
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  47. Thyroid Cancer 2item
  48. Type 2 Diabetes 3item