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  • Search results for: 'research area epigenetics parp'

Search results for: 'research area epigenetics parp'

Items 11-20 of 60

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  1. Ruxolitinib (INCB018424)
    A3012 Ruxolitinib (INCB018424)
     4 Citation
    Target: JAK
    Summary: JAK inhibitor
      insoluble in H2O; ≥15.32 mg/mL
  2. Tofacitinib (CP-690550) Citrate
    A4135 Tofacitinib (CP-690550) Citrate
     2 Citation
    Target: JAK
    Summary: Potent JAK inhibitor
      ≥25.22 mg/mL
  3. SRT1720 HCl
    A4180 SRT1720 HCl
     3 Citation
    Target: Sir2-like Family Deacetylases (Sirtuins)
    Summary: SIRT1 activator
      ≥25.3 mg/mL
  4. EX 527 (SEN0014196)
    A4181 EX 527 (SEN0014196)
     1 Citation
    Target: Sirtuin
    Summary: SIRT1 inhibitor
      insoluble in H2O; ≥12.43 mg/mL
  5. Belinostat (PXD101)
    A4096 Belinostat (PXD101)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: Hydroxamate-type HDAC inhibitor
      insoluble in H2O; ≥15.92 mg/mL
  6. Tubastatin A
    A4101 Tubastatin A
     6 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC6 inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥10.75 mg/mL
  7. Bardoxolone methyl
    A3221 Bardoxolone methyl
    Target: Nrf2
    Summary: IKK inhibitor, potent antioxidant inflammation modulator
      ≥25.3 mg/mL
  8. TC-A 2317 hydrochloride
    A4489 TC-A 2317 hydrochloride
    Target: Aurora Kinases
    Summary: Aurora kinase A inhibitor,potent and selective
      <39.29 mg/mL
  9. EPZ-6438
    A8221 EPZ-6438
     5 Citation
    Summary: EZH2 inhibitor, potent and selective
      ≥28.64 mg/mL
  10. LKB1 (AAK1 dual inhibitor)
    A3556 LKB1 (AAK1 dual inhibitor)
    Target: Pim
    Summary: Pim-1 kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥34.8 mg/mL

Items 11-20 of 60

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Category
  1. Apoptosis 1 item
  2. Chromatin/Epigenetics 57item
  3. Metabolism 1 item
  4. DNA Damage/DNA Repair 22item
  5. PI3K/Akt/mTOR Signaling 1 item
  6. Cell Cycle/Checkpoint 11item
  7. Ubiquitination/ Proteasome 1 item
  8. JAK/STAT Signaling 6item
  9. Angiogenesis 1 item
  10. Stem Cell 3item
Reversibility
  1. Reversible 2item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 16item
  3. PI3K 1 item
  4. Aurora Kinases 10item
  5. EZH2 2item
  6. Bromodomains 1 item
  7. FLT3 1 item
  8. PLK 1 item
  9. Bromodomain-containing proteins(BRDs) 1 item
  10. Hydrolase 1 item
  11. MEK 1 item
  12. DOT1L 1 item
  13. Nrf2 1 item
  14. Pim 2item
  15. Sir2-like Family Deacetylases (Sirtuins) 3item
  16. PP1 1 item
  17. PP2A 1 item
  18. Src 1 item
  19. JAK 3item
  20. DNA-PK 1 item
  21. Topoisomerases 1 item
  22. DNA Methyltransferases 3item
  23. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  24. CREBBP 2item
  25. EP300 2item
  26. PARP 4item
  27. Fatty-acid-binding proteins (FABPs) 1 item
  28. G9a 1 item
  29. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  30. Cytidine deaminases 1 item
  31. PP4 1 item
  32. c-RET 1 item
  33. Histone Acetyltransferases (HATs) 1 item
  34. Lck 1 item
  35. Sirtuin 1 item
Reported Experiments
  1. Animal Experiments 48item
  2. Cell Experiments 35item
Related Disease
  1. Acute Myeloid Leukemia 7item
  2. Bladder Cancer 2item
  3. Bladder Carcinoma 1 item
  4. Breast Cancer 13item
  5. Cancer 39item
  6. Cervical Cancer 1 item
  7. Chronic Lymphocytic Leukemia 1 item
  8. Colon Cancer 7item
  9. Colorectal Cancer 4item
  10. Diabetes 1 item
  11. Glioblastoma 1 item
  12. Glioma 2item
  13. Hepatic Cancer 1 item
  14. Hepatocellular Carcinoma 1 item
  15. HIV Infections 1 item
  16. Inflammatory Diseases 1 item
  17. Leukemia 3item
  18. Lung Cancer 4item
  19. Lymphoma 2item
  20. Melanoma 1 item
  21. Mixed Lineage Leukemia 1 item
  22. Multiple Myeloma 3item
  23. Myelofibrosis 1 item
  24. Myeloma 1 item
  25. Neuroblastoma 1 item
  26. Neuronal Protection 1 item
  27. Non-small Cell Lung Cancer 1 item
  28. Ovarian Cancer 5item
  29. Pancreatic Cancer 2item
  30. Prostate Cancer 10item
  31. Psoriasis 1 item
  32. Renal Cancer 1 item
  33. Renal Cell Carcinoma 2item
  34. Rheumatoid Arthritis 2item
  35. Thyroid Cancer 1 item
  36. Type 2 Diabetes 3item