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  • Search results for: 'research area epigenetics parp'

Search results for: 'research area epigenetics parp'

Items 61-70 of 173

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  1. EPZ-6438
    A8221 EPZ-6438
     5 Citation
    Summary: EZH2 inhibitor, potent and selective
      ≥28.64 mg/mL
  2. LKB1 (AAK1 dual inhibitor)
    A3556 LKB1 (AAK1 dual inhibitor)
    Target: Pim
    Summary: Pim-1 kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥34.8 mg/mL
  3. Reversine
    A3760 Reversine
    Target: Aurora Kinases
    Summary: A3 adenosine receptor antagonist,ARK-1/-2/-3 inhibitor
      insoluble in H2O; ≥19.65 mg/mL
  4. SCH-1473759
    A3804 SCH-1473759
    Summary: Aurora A/B inhibitor
      Soluble in DMSO
  5. ubiquitin specific protease 3 fragment
    A1097 ubiquitin specific protease 3 fragment
    Summary: Deubiquitinates uH2A/uH2B
      ≥93.7 mg/mL
  6. TG101348 (SAR302503)
    A4136 TG101348 (SAR302503)
     2 Citation
    Target: FLT3|JAK|c-RET
    Summary: JAK-2 inhibitor,potent and selective
      ≥26.23 mg/mL
  7. Baricitinib (LY3009104, INCB028050)
    A4141 Baricitinib (LY3009104, INCB028050)
     2 Citation
    Summary: JAK1/JAK2 inhibitor,selective orally bioavailable
      insoluble in EtOH; insoluble in H2O; ≥18.57 mg/mL
  8. EPZ5676
    A4166 EPZ5676
     1 Citation
    Target: DOT1L
    Summary: DOT1L inhibitor,potent and SAM competitive
      ≥28.15 mg/mL
  9. Scriptaid
    A4106 Scriptaid
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,novel and cell-permeable
      insoluble in H2O; ≥13.1 mg/mL
  10. ENMD-2076
    A4130 ENMD-2076
    Target: Aurora Kinases|FLT3|RET|Src|VEGFR3/FLT4|NTRK1/TRKA|CSF-1R/c-Fms
    Summary: Selective Aurora A/Flt3 inhibitor
      insoluble in H2O; ≥18.75 mg/mL

Items 61-70 of 173

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Category
  1. Proteases 1 item
  2. Apoptosis 7item
  3. Chromatin/Epigenetics 151item
  4. Metabolism 1 item
  5. Tyrosine Kinase 3item
  6. DNA Damage/DNA Repair 55item
  7. PI3K/Akt/mTOR Signaling 2item
  8. Microbiology & Virology 1 item
  9. Cell Cycle/Checkpoint 20item
  10. Ubiquitination/ Proteasome 1 item
  11. JAK/STAT Signaling 27item
  12. Angiogenesis 3item
  13. Stem Cell 4item
  14. Membrane Transporter/Ion Channel 1 item
  15. Cancer Biology 3item
  16. Neuroscience 2item
  17. Others 4item
  18. Immunology/Inflammation 2item
Specificity
  1. Selective 60item
Reversibility
  1. Reversible 2item
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 18item
  3. PI3K 1 item
  4. Aurora Kinases 16item
  5. EZH2 2item
  6. Bromodomains 4item
  7. FLT3 5item
  8. PLK 1 item
  9. VEGFR 2item
  10. RET 1 item
  11. Bromodomain-containing proteins(BRDs) 1 item
  12. Hydrolase 1 item
  13. MEK 1 item
  14. DOT1L 1 item
  15. FGFR 1 item
  16. Nrf2 1 item
  17. Pim 2item
  18. Sir2-like Family Deacetylases (Sirtuins) 4item
  19. PP1 1 item
  20. PP2A 1 item
  21. Src 3item
  22. Trk Receptors 1 item
  23. STAT 1 item
  24. JAK 9item
  25. DNA-PK 1 item
  26. Topoisomerases 1 item
  27. DNA Methyltransferases 3item
  28. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  29. CREBBP 2item
  30. EP300 2item
  31. LRRK2 1 item
  32. PARP 8item
  33. ALK 1 item
  34. Fatty-acid-binding proteins (FABPs) 1 item
  35. G9a 1 item
  36. Histamine H1 Receptors 1 item
  37. Hck 1 item
  38. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  39. Cytidine deaminases 1 item
  40. PP4 1 item
  41. c-RET 1 item
  42. VEGFR3/FLT4 1 item
  43. NTRK1/TRKA 1 item
  44. CSF-1R/c-Fms 1 item
  45. PTP 1 item
  46. p53 1 item
  47. Histone Acetyltransferases (HATs) 1 item
  48. Trx 1 item
  49. TYK2 1 item
  50. MUSK 1 item
  51. MAP3K 1 item
  52. Lck 1 item
  53. p21 1 item
  54. FGR 1 item
  55. YES 1 item
  56. Fyn 1 item
  57. ARG 1 item
  58. TRPC channel 1 item
  59. Sirtuin 1 item
Reported Experiments
  1. Animal Experiments 70item
  2. Cell Experiments 59item
Related Disease
  1. Acute Myeloid Leukemia 7item
  2. Bladder Cancer 2item
  3. Bladder Carcinoma 1 item
  4. Breast Cancer 13item
  5. Cancer 52item
  6. Cervical Cancer 2item
  7. Chronic Lymphocytic Leukemia 1 item
  8. Colon Cancer 7item
  9. Colorectal Cancer 4item
  10. Diabetes 1 item
  11. Glioblastoma 1 item
  12. Glioma 2item
  13. Hepatic Cancer 1 item
  14. Hepatocellular Carcinoma 1 item
  15. HIV 1 item
  16. HIV Infections 1 item
  17. Inflammatory Diseases 2item
  18. Leukemia 3item
  19. Lung Cancer 4item
  20. Lymphoma 2item
  21. Melanoma 1 item
  22. Mixed Lineage Leukemia 1 item
  23. Multiple Myeloma 3item
  24. Myelofibrosis 1 item
  25. Myeloma 1 item
  26. Neuroblastoma 1 item
  27. Neuronal Protection 1 item
  28. Non-small Cell Lung Cancer 1 item
  29. Ovarian Cancer 5item
  30. Pancreatic Cancer 2item
  31. Prostate Cancer 10item
  32. Psoriasis 1 item
  33. Renal Cancer 1 item
  34. Renal Cell Carcinoma 2item
  35. Rheumatoid Arthritis 2item
  36. Thyroid Cancer 1 item
  37. Type 2 Diabetes 3item