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  • Search results for: 'research area epigenetics parp'

Search results for: 'research area epigenetics parp'

Items 41-50 of 151

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  1. Ruxolitinib (INCB018424)
    A3012 Ruxolitinib (INCB018424)
     4 Citation
    Target: JAK
    Summary: JAK inhibitor
      insoluble in H2O; ≥15.32 mg/mL
  2. Tofacitinib (CP-690550) Citrate
    A4135 Tofacitinib (CP-690550) Citrate
     2 Citation
    Target: JAK
    Summary: Potent JAK inhibitor
      ≥25.22 mg/mL
  3. AZD1480
    A4137 AZD1480
    Target: JAK
    Summary: JAK2 inhibitor,ATP-competitive and novel
      insoluble in H2O; ≥93.8 mg/mL
  4. CYT387
    A4143 CYT387
     1 Citation
    Summary: JAK-1/-2 inhibitor,ATP competitive
      insoluble in EtOH; insoluble in H2O; ≥20.7 mg/mL
  5. CEP-33779
    A4146 CEP-33779
     1 Citation
    Summary: JAK2 inhibitor,highly selective
      ≥23.15 mg/mL
  6. LY2784544
    A4147 LY2784544
    Target: Aurora Kinases|FLT3|VEGFR|FGFR|Trk Receptors|JAK|ALK|TYK2|MUSK|MAP3K
    Summary: JAK2 inhibitor,highly potent and selective
      ≥23.5 mg/mL
  7. SRT1720 HCl
    A4180 SRT1720 HCl
     3 Citation
    Target: Sir2-like Family Deacetylases (Sirtuins)
    Summary: SIRT1 activator
      ≥25.3 mg/mL
  8. EX 527 (SEN0014196)
    A4181 EX 527 (SEN0014196)
     1 Citation
    Target: Sirtuin
    Summary: SIRT1 inhibitor
      insoluble in H2O; ≥12.43 mg/mL
  9. SGI-1776 free base
    A4192 SGI-1776 free base
     3 Citation
    Summary: Pim kinase inhibitor,ATP-competitive
      ≥40.5 mg/mL
  10. Resminostat (RAS2410)
    A4108 Resminostat (RAS2410)
     1 Citation
    Summary: Potent HDAC inhibitor
      Soluble in DMSO

Items 41-50 of 151

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  1. Category Chromatin/Epigenetics Remove This Item
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  1. Bromodomain 6item
  2. Aurora Kinase 19item
  3. DNA Methyltransferase 6item
  4. HDAC 22item
  5. Histone Acetyltransferases 1 item
  6. Histone Demethylases 1 item
  7. Histone Methyltransferase 12item
  8. HIF 5item
  9. JAK 20item
  10. MBT Domains 1 item
  11. PARP 28item
  12. Pim 7item
  13. Protein Ser/Thr Phosphatases 15item
  14. RNA Polymerase 3item
  15. Sirtuin 6item
Specificity
  1. Selective 57item
Reversibility
  1. Reversible 2item
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 18item
  3. Aurora Kinases 16item
  4. EZH2 2item
  5. Bromodomains 4item
  6. FLT3 5item
  7. VEGFR 2item
  8. RET 1 item
  9. Hydrolase 1 item
  10. MEK 1 item
  11. DOT1L 1 item
  12. FGFR 1 item
  13. Nrf2 1 item
  14. Pim 2item
  15. Sir2-like Family Deacetylases (Sirtuins) 4item
  16. PP1 1 item
  17. PP2A 1 item
  18. Src 3item
  19. Trk Receptors 1 item
  20. STAT 1 item
  21. JAK 9item
  22. Topoisomerases 1 item
  23. DNA Methyltransferases 3item
  24. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  25. CREBBP 2item
  26. EP300 2item
  27. LRRK2 1 item
  28. PARP 8item
  29. ALK 1 item
  30. G9a 1 item
  31. Hck 1 item
  32. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  33. Cytidine deaminases 1 item
  34. PP4 1 item
  35. c-RET 1 item
  36. VEGFR3/FLT4 1 item
  37. NTRK1/TRKA 1 item
  38. CSF-1R/c-Fms 1 item
  39. PTP 1 item
  40. p53 1 item
  41. Histone Acetyltransferases (HATs) 1 item
  42. Trx 1 item
  43. TYK2 1 item
  44. MUSK 1 item
  45. MAP3K 1 item
  46. Lck 1 item
  47. p21 1 item
  48. FGR 1 item
  49. YES 1 item
  50. Fyn 1 item
  51. ARG 1 item
  52. Sirtuin 1 item
Reported Experiments
  1. Animal Experiments 64item
  2. Cell Experiments 53item
Related Disease
  1. Acute Myeloid Leukemia 7item
  2. Bladder Cancer 2item
  3. Bladder Carcinoma 1 item
  4. Breast Cancer 13item
  5. Cancer 49item
  6. Cervical Cancer 2item
  7. Chronic Lymphocytic Leukemia 1 item
  8. Colon Cancer 6item
  9. Colorectal Cancer 4item
  10. Diabetes 1 item
  11. Glioblastoma 1 item
  12. Glioma 2item
  13. Hepatic Cancer 1 item
  14. Hepatocellular Carcinoma 1 item
  15. HIV 1 item
  16. HIV Infections 1 item
  17. Inflammatory Diseases 2item
  18. Leukemia 3item
  19. Lung Cancer 4item
  20. Lymphoma 2item
  21. Melanoma 1 item
  22. Mixed Lineage Leukemia 1 item
  23. Multiple Myeloma 3item
  24. Myelofibrosis 1 item
  25. Myeloma 1 item
  26. Neuroblastoma 1 item
  27. Neuronal Protection 1 item
  28. Non-small Cell Lung Cancer 1 item
  29. Ovarian Cancer 5item
  30. Pancreatic Cancer 2item
  31. Prostate Cancer 10item
  32. Psoriasis 1 item
  33. Renal Cancer 1 item
  34. Renal Cell Carcinoma 2item
  35. Rheumatoid Arthritis 2item
  36. Thyroid Cancer 1 item
  37. Type 2 Diabetes 2item