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  • Search results for: 'research area epigenetics parp'

Search results for: 'research area epigenetics parp'

Items 71-80 of 260

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  1. TG101348 (SAR302503)
    A4136 TG101348 (SAR302503)
     2 Citation
    Target: FLT3|JAK|c-RET
    Summary: JAK-2 inhibitor,potent and selective
      ≥26.23 mg/mL
  2. Baricitinib (LY3009104, INCB028050)
    A4141 Baricitinib (LY3009104, INCB028050)
     2 Citation
    Summary: JAK1/JAK2 inhibitor,selective orally bioavailable
      insoluble in EtOH; insoluble in H2O; ≥18.57 mg/mL
  3. EPZ5676
    A4166 EPZ5676
     1 Citation
    Target: DOT1L
    Summary: DOT1L inhibitor,potent and SAM competitive
      ≥28.15 mg/mL
  4. Scriptaid
    A4106 Scriptaid
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,novel and cell-permeable
      insoluble in H2O; ≥13.1 mg/mL
  5. ENMD-2076
    A4130 ENMD-2076
    Target: Aurora Kinases|FLT3|RET|Src|VEGFR3/FLT4|NTRK1/TRKA|CSF-1R/c-Fms
    Summary: Selective Aurora A/Flt3 inhibitor
      insoluble in H2O; ≥18.75 mg/mL
  6. CCT137690
    A4132 CCT137690
    Target: Aurora Kinases
    Summary: Aurora A/B/C inhibitor
      insoluble in H2O; insoluble in EtOH; ≥6.89 mg/mL
  7. LAQ824 (NVP-LAQ824,Dacinostat)
    A4103 LAQ824 (NVP-LAQ824,Dacinostat)
     1 Citation
    Summary: HDAC inhibitor,potent and novel
      insoluble in H2O; insoluble in EtOH; ≥17.45 mg/mL
  8. AR-42 (OSU-HDAC42)
    A4104 AR-42 (OSU-HDAC42)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,novel and potent
      insoluble in EtOH; insoluble in H2O; ≥15.62 mg/mL
  9. MLN8054
    A4114 MLN8054
    Target: Aurora Kinases
    Summary: Aurora A inhibitor
      insoluble in EtOH; insoluble in H2O; ≥39.05 mg/mL
  10. JNJ-7706621
    A4115 JNJ-7706621
     1 Citation
    Target: Cyclin-Dependent Kinases|Aurora Kinases
    Summary: Potent CDK/Aurora kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥19.7 mg/mL

Items 71-80 of 260

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  1. Signaling Pathways 173item
  2. Natural Products 2item
  3. Protein 12item
  4. Kits 1 item
  5. Screening Library 31item
  6. Peptides 1 item
  7. Probes & Dyes 1 item
  8. Cell Biology 3item
  9. Peptides & Proteins 46item
  10. Protein & Immunology 1 item
Specificity
  1. Selective 63item
Reversibility
  1. Reversible 2item
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 18item
  3. PI3K 1 item
  4. Aurora Kinases 16item
  5. EZH2 2item
  6. Bromodomains 4item
  7. FLT3 5item
  8. PLK 1 item
  9. VEGFR 2item
  10. RET 1 item
  11. Bromodomain-containing proteins(BRDs) 1 item
  12. Hydrolase 1 item
  13. MEK 1 item
  14. DOT1L 1 item
  15. FGFR 1 item
  16. Nrf2 1 item
  17. Pim 2item
  18. Sir2-like Family Deacetylases (Sirtuins) 4item
  19. PP1 1 item
  20. PP2A 1 item
  21. Src 3item
  22. Trk Receptors 2item
  23. STAT 1 item
  24. EGFR 1 item
  25. JAK 9item
  26. DNA-PK 1 item
  27. Topoisomerases 1 item
  28. DNA Methyltransferases 3item
  29. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  30. CREBBP 2item
  31. EP300 2item
  32. LRRK2 1 item
  33. PARP 9item
  34. ALK 1 item
  35. Fatty-acid-binding proteins (FABPs) 1 item
  36. G9a 1 item
  37. Histamine H1 Receptors 1 item
  38. Hck 1 item
  39. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  40. Cytidine deaminases 1 item
  41. PP4 1 item
  42. c-RET 1 item
  43. VEGFR3/FLT4 1 item
  44. NTRK1/TRKA 1 item
  45. CSF-1R/c-Fms 1 item
  46. PTP 1 item
  47. p53 1 item
  48. Histone Acetyltransferases (HATs) 1 item
  49. Trx 1 item
  50. TYK2 1 item
  51. MUSK 1 item
  52. MAP3K 1 item
  53. Lck 1 item
  54. p21 1 item
  55. FGR 1 item
  56. YES 1 item
  57. Fyn 1 item
  58. ARG 1 item
  59. TRPC channel 1 item
  60. Sirtuin 1 item
Reported Experiments
  1. Animal Experiments 71item
  2. Cell Experiments 62item
Related Disease
  1. Acute Myeloid Leukemia 7item
  2. Bladder Cancer 2item
  3. Bladder Carcinoma 1 item
  4. Breast Cancer 13item
  5. Cancer 52item
  6. Cervical Cancer 2item
  7. Chronic Lymphocytic Leukemia 1 item
  8. Colon Cancer 7item
  9. Colorectal Cancer 4item
  10. Diabetes 1 item
  11. Friedreich's Ataxia 1 item
  12. Glioblastoma 1 item
  13. Glioma 2item
  14. Hepatic Cancer 1 item
  15. Hepatocellular Carcinoma 1 item
  16. HIV 1 item
  17. HIV Infections 1 item
  18. Inflammatory Diseases 2item
  19. Leukemia 3item
  20. Lung Cancer 4item
  21. Lymphoma 2item
  22. Melanoma 1 item
  23. Mixed Lineage Leukemia 1 item
  24. Multiple Myeloma 3item
  25. Myelofibrosis 1 item
  26. Myeloma 1 item
  27. Neuroblastoma 1 item
  28. Neuronal Protection 1 item
  29. Non-small Cell Lung Cancer 1 item
  30. Ovarian Cancer 5item
  31. Pancreatic Cancer 2item
  32. Prostate Cancer 10item
  33. Psoriasis 1 item
  34. Renal Cancer 1 item
  35. Renal Cell Carcinoma 2item
  36. Rheumatoid Arthritis 2item
  37. Thyroid Cancer 1 item
  38. Type 2 Diabetes 4item