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  • Search results for: 'research area jak stat signaling egfr'

Search results for: 'research area jak stat signaling egfr'

Items 11-20 of 368

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  1. Fludarabine Phosphate (Fludara)
    A8317 Fludarabine Phosphate (Fludara)
     2 Citation
    Target: STAT
    Summary: Inhibits STAT1 activation and DNA synthesis
      insoluble in EtOH; ≥17.6 mg/mL
  2. Fludarabine
    A5424 Fludarabine
    Summary: DNA synthsis inhibitor
      insoluble in H2O; insoluble in EtOH; ≥9.25 mg/mL
  3. WZ3146
    A8881 WZ3146
    Summary: Mutant EGFR inhibitor, potent and irreversible
      ≥23.25 mg/mL
  4. WZ4002
    A1389 WZ4002
    Summary: Mutant-selective EGFR inhibitor(L858R,T790M), irreversible and potent
      ≥24.7 mg/mL
  5. Erlotinib Hydrochloride
    A8234 Erlotinib Hydrochloride
     2 Citation
    Summary: Selective EGFR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥6.44 mg/mL
  6. Afatinib (BIBW2992)
    A8247 Afatinib (BIBW2992)
     1 Citation
    Target: EGFR
    Summary: Irreversible EGFR/HER2 inhibitor
      ≥24.3 mg/mL
  7. WZ8040
    A1393 WZ8040
    Target: EGFR
    Summary: EGFR T790M inhibitor,irreversible amd potent
      ≥24.05 mg/mL
  8. Lapatinib Ditosylate
    A3967 Lapatinib Ditosylate
    Target: EGFR|ErbB-2
    Summary: EGFR/HER2 inhibitor,potent and selective
      ≥24.3 mg/mL
  9. AEE788 (NVP-AEE788)
    A5455 AEE788 (NVP-AEE788)
    Summary: EGFR/HER-2/VEGFR inhibitor
      ≥22.05 mg/mL
  10. AG-490
    A4139 AG-490
     3 Citation
    Target: EGFR|JAK
    Summary: JAK2/EGFR inhibitor
      insoluble in H2O; ≥14.7 mg/mL

Items 11-20 of 368

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  1. Proteases 4item
  2. Apoptosis 10item
  3. Chromatin/Epigenetics 45item
  4. Metabolism 5item
  5. MAPK Signaling 34item
  6. Tyrosine Kinase 92item
  7. DNA Damage/DNA Repair 8item
  8. PI3K/Akt/mTOR Signaling 58item
  9. Microbiology & Virology 1 item
  10. Cell Cycle/Checkpoint 8item
  11. Ubiquitination/ Proteasome 2item
  12. JAK/STAT Signaling 83item
  13. TGF-β / Smad Signaling 23item
  14. Angiogenesis 1 item
  15. GPCR/G protein 2item
  16. Stem Cell 39item
  17. Membrane Transporter/Ion Channel 3item
  18. Cancer Biology 12item
  19. Endocrinology and Hormones 16item
  20. Neuroscience 17item
  21. Obesity, Appetite Control & Diabetes 4item
  22. Other Signal Transduction 42item
  23. Others 12item
  24. Immunology/Inflammation 8item
  25. Cardiovascular 24item
Specificity
  1. Selective 110item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 10item
  2. Irreversible 6item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 9item
  4. PI3K 13item
  5. Raf 8item
  6. Aurora Kinases 1 item
  7. mTOR 8item
  8. Androgen Receptors 1 item
  9. FLT3 2item
  10. GSK-3 7item
  11. P-glycoprotein (P-gp) 1 item
  12. VEGFR 10item
  13. PDGFR 4item
  14. Phosphodiesterases (PDEs) 1 item
  15. p38 4item
  16. PKB 1 item
  17. JNK 4item
  18. Bcr-Abl 1 item
  19. MEK 5item
  20. PORCN 1 item
  21. FGFR 5item
  22. Nrf2 1 item
  23. GABAB Receptors 1 item
  24. Smoothened 1 item
  25. MET 1 item
  26. Src 3item
  27. Trk Receptors 1 item
  28. NMDA Receptors 1 item
  29. STAT 6item
  30. EGFR 23item
  31. Hedgehog 1 item
  32. BMP and Other Activin Receptors 2item
  33. JAK 19item
  34. Syk 2item
  35. DNA-PK 1 item
  36. HSP90 1 item
  37. TNKS 1 item
  38. ErbB 5item
  39. Toll-like receptors (TLRs) 1 item
  40. ERK 2item
  41. c-MET 1 item
  42. PKC 7item
  43. HER2 3item
  44. Melanocortin (MC) Receptors 1 item
  45. ALK 2item
  46. PKG 1 item
  47. PKA 4item
  48. Fatty-acid-binding proteins (FABPs) 1 item
  49. RSK 1 item
  50. Histamine H1 Receptors 1 item
  51. MNK 1 item
  52. NO Donors / Precursors 1 item
  53. IL Receptors 1 item
  54. AChE 1 item
  55. Insulin Receptors 1 item
  56. IRG-1R 1 item
  57. BACE 1 item
  58. c-RET 1 item
  59. p70 rsk 1 item
  60. sodium channels 1 item
  61. insulin 1 item
  62. Smoothened receptor 1 item
  63. Nrf2/ARE signal 1 item
  64. PPAR 1 item
  65. Antibiotic 1 item
  66. ErbB-2 1 item
  67. Prk 1 item
  68. ICAM 1 item
  69. Rho 1 item
  70. TYK2 2item
  71. MUSK 1 item
  72. MAP3K 1 item
  73. Thrombin Receptor 1 item
  74. prolactin secretion 1 item
  75. gonadotropin release 1 item
  76. TRPC channel 1 item
  77. FKBP 1 item
Reported Experiments
  1. Animal Experiments 152item
  2. Cell Experiments 118item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 3item
  3. Bladder Cancer 2item
  4. Breast Cancer 27item
  5. Cancer 102item
  6. Cervical Cancer 2item
  7. Colon Cancer 10item
  8. Colon Carcinoma 1 item
  9. Colorectal Cancer 11item
  10. Glioblastoma 11item
  11. Glioma 3item
  12. Heart Failure 1 item
  13. Hepatocellular Carcinoma 1 item
  14. HIV Infections 1 item
  15. Immunological Diseases 1 item
  16. Inflammatory Bowel Disease 1 item
  17. Leukemia 9item
  18. Liver Cancer 2item
  19. Lung Cancer 8item
  20. Lymphoma 3item
  21. Melanoma 6item
  22. Multiple Myeloma 2item
  23. Myelofibrosis 1 item
  24. Myeloma 1 item
  25. Neuroblastoma 2item
  26. Non-small Cell Lung Cancer 6item
  27. Ovarian Cancer 8item
  28. Pancreatic Cancer 11item
  29. Pancreatic Carcinoma 2item
  30. Prostate Cancer 14item
  31. Psoriasis 1 item
  32. Pulmonary Arterial Hypertension 1 item
  33. Pulmonary Fibrosis 1 item
  34. Renal Cancer 1 item
  35. Renal Cell Carcinoma 1 item
  36. Rheumatoid Arthritis 4item
  37. Thyroid Cancer 2item
  38. Type 2 Diabetes 2item