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  • Search results for: 'research area jak stat signaling egfr'

Search results for: 'research area jak stat signaling egfr'

Items 11-20 of 110

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  1. CP-724714
    A2412 CP-724714
    Target: VEGFR|PDGFR|Bcr-Abl|Src|EGFR|c-MET|Insulin Receptors|IRG-1R
    Summary: HER2 inhibitor,potent and selective
      ≥23.5 mg/mL
  2. Ruxolitinib (INCB018424)
    A3012 Ruxolitinib (INCB018424)
     4 Citation
    Target: JAK
    Summary: JAK inhibitor
      insoluble in H2O; ≥15.32 mg/mL
  3. TG101348 (SAR302503)
    A4136 TG101348 (SAR302503)
     2 Citation
    Target: FLT3|JAK|c-RET
    Summary: JAK-2 inhibitor,potent and selective
      ≥26.23 mg/mL
  4. XL019
    A3937 XL019
    Target: JAK
    Summary: JAK2 inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥11.125 mg/mL
  5. NVP-BSK805 2HCl
    A4148 NVP-BSK805 2HCl
    Target: JAK
    Summary: JAK2 inhibitor
      ≥30.8 mg/mL
  6. ZM 39923 HCl
    A4151 ZM 39923 HCl
    Target: JAK
    Summary: JAK3 inhibitor,potent and selective
  7. BMS-911543
    A4152 BMS-911543
    Target: JAK
    Summary: JAK2 inhibitor,selective small molecule
      ≥43.3 mg/mL
  8. Wnt-C59
    A8685 Wnt-C59
     2 Citation
    Target: PORCN
    Summary: PORCN inhibitor,highly potent and selective
      .95 mg/mL
      insoluble in H2O; ≥18
  9. Dabrafenib Mesylate (GSK-2118436)
    A3347 Dabrafenib Mesylate (GSK-2118436)
    Target: Raf
    Summary: Inhibitor of BRAF(V600) mutants
      ≥30.75 mg/mL
  10. AC480 (BMS-599626)
    A2822 AC480 (BMS-599626)
    Target: EGFR
    Summary: HER1/2 inhibitor,selective and efficacious
      ≥28.35 mg/mL

Items 11-20 of 110

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Category
  1. Proteases 2item
  2. Chromatin/Epigenetics 12item
  3. Metabolism 3item
  4. MAPK Signaling 19item
  5. Tyrosine Kinase 27item
  6. DNA Damage/DNA Repair 2item
  7. PI3K/Akt/mTOR Signaling 24item
  8. Ubiquitination/ Proteasome 1 item
  9. JAK/STAT Signaling 28item
  10. TGF-β / Smad Signaling 13item
  11. Stem Cell 13item
  12. Membrane Transporter/Ion Channel 1 item
  13. Endocrinology and Hormones 1 item
  14. Neuroscience 3item
  15. Obesity, Appetite Control & Diabetes 2item
  16. Other Signal Transduction 2item
  17. Immunology/Inflammation 1 item
  18. Cardiovascular 1 item
Reversibility
  1. Reversible 7item
  2. Irreversible 3item
Target
  1. Akt 4item
  2. PI3K 10item
  3. Raf 6item
  4. mTOR 6item
  5. Androgen Receptors 1 item
  6. FLT3 1 item
  7. GSK-3 5item
  8. P-glycoprotein (P-gp) 1 item
  9. VEGFR 6item
  10. PDGFR 3item
  11. Phosphodiesterases (PDEs) 1 item
  12. p38 4item
  13. PKB 1 item
  14. JNK 4item
  15. Bcr-Abl 1 item
  16. MEK 5item
  17. PORCN 1 item
  18. FGFR 3item
  19. Nrf2 1 item
  20. GABAB Receptors 1 item
  21. Smoothened 1 item
  22. MET 1 item
  23. Src 2item
  24. STAT 4item
  25. EGFR 14item
  26. Hedgehog 1 item
  27. BMP and Other Activin Receptors 2item
  28. JAK 11item
  29. Syk 2item
  30. HSP90 1 item
  31. TNKS 1 item
  32. ErbB 2item
  33. Toll-like receptors (TLRs) 1 item
  34. ERK 1 item
  35. c-MET 1 item
  36. PKC 3item
  37. HER2 2item
  38. Melanocortin (MC) Receptors 1 item
  39. Fatty-acid-binding proteins (FABPs) 1 item
  40. NO Donors / Precursors 1 item
  41. IL Receptors 1 item
  42. Insulin Receptors 1 item
  43. IRG-1R 1 item
  44. c-RET 1 item
  45. TYK2 1 item
Reported Experiments
  1. Animal Experiments 102item
  2. Cell Experiments 62item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 3item
  3. Bladder Cancer 2item
  4. Breast Cancer 25item
  5. Cancer 75item
  6. Cervical Cancer 2item
  7. Colon Cancer 9item
  8. Colon Carcinoma 1 item
  9. Colorectal Cancer 11item
  10. Glioblastoma 11item
  11. Glioma 3item
  12. Hepatocellular Carcinoma 1 item
  13. HIV Infections 1 item
  14. Immunological Diseases 1 item
  15. Inflammatory Bowel Disease 1 item
  16. Leukemia 8item
  17. Liver Cancer 2item
  18. Lung Cancer 8item
  19. Lymphoma 3item
  20. Melanoma 5item
  21. Multiple Myeloma 2item
  22. Myelofibrosis 1 item
  23. Myeloma 1 item
  24. Neuroblastoma 2item
  25. Non-small Cell Lung Cancer 6item
  26. Ovarian Cancer 7item
  27. Pancreatic Cancer 11item
  28. Pancreatic Carcinoma 2item
  29. Prostate Cancer 14item
  30. Psoriasis 1 item
  31. Pulmonary Arterial Hypertension 1 item
  32. Pulmonary Fibrosis 1 item
  33. Renal Cancer 1 item
  34. Renal Cell Carcinoma 1 item
  35. Rheumatoid Arthritis 4item
  36. Thyroid Cancer 2item
  37. Type 2 Diabetes 2item