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  • Search results for: 'research area jak stat signaling egfr'

Search results for: 'research area jak stat signaling egfr'

Items 31-40 of 152

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  1. SB 203580
    A8254 SB 203580
     9 Citation
    Target: p38|PKB
    Summary: P38 MAP kinase inhibitor
      insoluble in H2O; ≥18.872 mg/mL
  2. Tofacitinib (CP-690550,Tasocitinib)
    A4138 Tofacitinib (CP-690550,Tasocitinib)
     1 Citation
    Target: JAK
    Summary: Janus kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥15.6 mg/mL
  3. LY2784544
    A4147 LY2784544
    Target: Aurora Kinases|FLT3|VEGFR|FGFR|Trk Receptors|JAK|ALK|TYK2|MUSK|MAP3K
    Summary: JAK2 inhibitor,highly potent and selective
      ≥23.5 mg/mL
  4. Bardoxolone methyl
    A3221 Bardoxolone methyl
    Target: Nrf2
    Summary: IKK inhibitor, potent antioxidant inflammation modulator
      ≥25.3 mg/mL
  5. ICG 001
    A8217 ICG 001
     1 Citation
    Summary: Wnt/β-catenin pathway inhibitor
      ≥27.43 mg/mL
  6. LDN-193189
    A8324 LDN-193189
    Target: BMP and Other Activin Receptors
    Summary: ALK inhibitor,potent and selective
      insoluble in DMSO; insoluble in EtOH; insoluble in H2O
  7. LY2940680
    A8651 LY2940680
    Target: Smoothened receptor
    Summary: Hedgehog/SMO antagonist,inhibits Hh signaling
  8. SB-505124 hydrochloride
    A3799 SB-505124 hydrochloride
    Target: ALK
    Summary: ALK5/ALK4/ALK7 inhibitor in TGF-β/activin signalling,selective
  9. TAK-632
    A8226 TAK-632
    Target: Raf
    Summary: Pan-RAF inhibitor,potent and selective
      ≥27.75 mg/mL
  10. GDC-0879
    A5071 GDC-0879
     1 Citation
    Target: Raf
    Summary: B-Raf inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥16.7 mg/mL

Items 31-40 of 152

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  1. Category Signaling Pathways Remove This Item
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Category
  1. Proteases 3item
  2. Apoptosis 2item
  3. Chromatin/Epigenetics 19item
  4. Metabolism 4item
  5. MAPK Signaling 18item
  6. Tyrosine Kinase 36item
  7. DNA Damage/DNA Repair 5item
  8. PI3K/Akt/mTOR Signaling 33item
  9. Cell Cycle/Checkpoint 1 item
  10. Ubiquitination/ Proteasome 1 item
  11. JAK/STAT Signaling 40item
  12. TGF-β / Smad Signaling 15item
  13. Stem Cell 14item
  14. Membrane Transporter/Ion Channel 2item
  15. Cancer Biology 1 item
  16. Endocrinology and Hormones 2item
  17. Neuroscience 8item
  18. Obesity, Appetite Control & Diabetes 2item
  19. Other Signal Transduction 6item
  20. Others 2item
  21. Immunology/Inflammation 1 item
  22. Cardiovascular 5item
Specificity
  1. Selective 102item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 9item
  2. Irreversible 6item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 9item
  4. PI3K 13item
  5. Raf 8item
  6. Aurora Kinases 1 item
  7. mTOR 8item
  8. Androgen Receptors 1 item
  9. FLT3 2item
  10. GSK-3 6item
  11. P-glycoprotein (P-gp) 1 item
  12. VEGFR 10item
  13. PDGFR 4item
  14. Phosphodiesterases (PDEs) 1 item
  15. p38 4item
  16. PKB 1 item
  17. JNK 2item
  18. Bcr-Abl 1 item
  19. MEK 4item
  20. PORCN 1 item
  21. FGFR 5item
  22. Nrf2 1 item
  23. GABAB Receptors 1 item
  24. Smoothened 1 item
  25. MET 1 item
  26. Src 3item
  27. Trk Receptors 1 item
  28. NMDA Receptors 1 item
  29. STAT 6item
  30. EGFR 21item
  31. Hedgehog 1 item
  32. BMP and Other Activin Receptors 2item
  33. JAK 17item
  34. Syk 2item
  35. DNA-PK 1 item
  36. HSP90 1 item
  37. TNKS 1 item
  38. ErbB 5item
  39. Toll-like receptors (TLRs) 1 item
  40. ERK 2item
  41. c-MET 1 item
  42. PKC 7item
  43. HER2 3item
  44. Melanocortin (MC) Receptors 1 item
  45. ALK 2item
  46. PKG 1 item
  47. PKA 4item
  48. Fatty-acid-binding proteins (FABPs) 1 item
  49. RSK 1 item
  50. Histamine H1 Receptors 1 item
  51. MNK 1 item
  52. NO Donors / Precursors 1 item
  53. IL Receptors 1 item
  54. AChE 1 item
  55. Insulin Receptors 1 item
  56. IRG-1R 1 item
  57. BACE 1 item
  58. c-RET 1 item
  59. p70 rsk 1 item
  60. insulin 1 item
  61. Smoothened receptor 1 item
  62. Antibiotic 1 item
  63. ErbB-2 1 item
  64. Prk 1 item
  65. ICAM 1 item
  66. Rho 1 item
  67. TYK2 2item
  68. MUSK 1 item
  69. MAP3K 1 item
  70. Thrombin Receptor 1 item
  71. prolactin secretion 1 item
  72. gonadotropin release 1 item
  73. TRPC channel 1 item
  74. FKBP 1 item
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