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  • Search results for: 'research area jak stat signaling egfr'

Search results for: 'research area jak stat signaling egfr'

Items 31-40 of 110

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  1. CC-930
    A3288 CC-930
    Target: JNK
    Summary: JNK inhibitor,potent and selective
      Soluble in DMSO
  2. JNK-IN-7
    A3519 JNK-IN-7
    Target: JNK
    Summary: Selective JNK inhibitor
      ≥24.7 mg/mL
  3. Trametinib (GSK1120212)
    A3018 Trametinib (GSK1120212)
     7 Citation
    Target: MEK
    Summary: MEK1 and MEK2 inhibitor, potent and selective
      insoluble in H2O; insoluble in EtOH; ≥15.38 mg/mL
  4. CHIR-99021 (CT99021) HCl
    A8396 CHIR-99021 (CT99021) HCl
    Target: GSK-3
    Summary: GSK-3α/β inhibitor
      ≥25.1 mg/mL
  5. CHIR-99021 (CT99021)
    A3011 CHIR-99021 (CT99021)
     2 Citation
    Target: GSK-3
    Summary: GSK-3 inhibitor, Cell-permeable, ATP-competitive
      ≥23.27 mg/mL
  6. Gefitinib hydrochloride
    A3433 Gefitinib hydrochloride
    Target: EGFR
    Summary: Potent EGFR inhibitor
      insoluble in EtOH; ≥4.28 mg/mL
  7. XAV-939
    A1877 XAV-939
     1 Citation
    Target: TNKS
    Summary: Tankyrase 1/2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥15.62 mg/mL
  8. XL147
    A5112 XL147
    Target: PI3K
    Summary: PI3K inhibitor,selective and reversible
      ≥22.45 mg/mL
  9. TGX-221
    A2681 TGX-221
    Target: PI3K
    Summary: PI3Kβ inhibitor,potent,selective and ATP competitive
      insoluble in H2O; insoluble in EtOH; ≥68.7 mg/mL
  10. AS-605240
    A5176 AS-605240
    Target: PI3K
    Summary: Potent and selective PI 3-Kγ inhibitor
      insoluble in H2O; insoluble in EtOH; ≥4.28 mg/mL

Items 31-40 of 110

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Category
  1. Proteases 2item
  2. Chromatin/Epigenetics 12item
  3. Metabolism 3item
  4. MAPK Signaling 19item
  5. Tyrosine Kinase 27item
  6. DNA Damage/DNA Repair 2item
  7. PI3K/Akt/mTOR Signaling 24item
  8. Ubiquitination/ Proteasome 1 item
  9. JAK/STAT Signaling 28item
  10. TGF-β / Smad Signaling 13item
  11. Stem Cell 13item
  12. Membrane Transporter/Ion Channel 1 item
  13. Endocrinology and Hormones 1 item
  14. Neuroscience 3item
  15. Obesity, Appetite Control & Diabetes 2item
  16. Other Signal Transduction 2item
  17. Immunology/Inflammation 1 item
  18. Cardiovascular 1 item
Reversibility
  1. Reversible 7item
  2. Irreversible 3item
Target
  1. Akt 4item
  2. PI3K 10item
  3. Raf 6item
  4. mTOR 6item
  5. Androgen Receptors 1 item
  6. FLT3 1 item
  7. GSK-3 5item
  8. P-glycoprotein (P-gp) 1 item
  9. VEGFR 6item
  10. PDGFR 3item
  11. Phosphodiesterases (PDEs) 1 item
  12. p38 4item
  13. PKB 1 item
  14. JNK 4item
  15. Bcr-Abl 1 item
  16. MEK 5item
  17. PORCN 1 item
  18. FGFR 3item
  19. Nrf2 1 item
  20. GABAB Receptors 1 item
  21. Smoothened 1 item
  22. MET 1 item
  23. Src 2item
  24. STAT 4item
  25. EGFR 14item
  26. Hedgehog 1 item
  27. BMP and Other Activin Receptors 2item
  28. JAK 11item
  29. Syk 2item
  30. HSP90 1 item
  31. TNKS 1 item
  32. ErbB 2item
  33. Toll-like receptors (TLRs) 1 item
  34. ERK 1 item
  35. c-MET 1 item
  36. PKC 3item
  37. HER2 2item
  38. Melanocortin (MC) Receptors 1 item
  39. Fatty-acid-binding proteins (FABPs) 1 item
  40. NO Donors / Precursors 1 item
  41. IL Receptors 1 item
  42. Insulin Receptors 1 item
  43. IRG-1R 1 item
  44. c-RET 1 item
  45. TYK2 1 item
Reported Experiments
  1. Animal Experiments 102item
  2. Cell Experiments 62item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 3item
  3. Bladder Cancer 2item
  4. Breast Cancer 25item
  5. Cancer 75item
  6. Cervical Cancer 2item
  7. Colon Cancer 9item
  8. Colon Carcinoma 1 item
  9. Colorectal Cancer 11item
  10. Glioblastoma 11item
  11. Glioma 3item
  12. Hepatocellular Carcinoma 1 item
  13. HIV Infections 1 item
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  16. Leukemia 8item
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  18. Lung Cancer 8item
  19. Lymphoma 3item
  20. Melanoma 5item
  21. Multiple Myeloma 2item
  22. Myelofibrosis 1 item
  23. Myeloma 1 item
  24. Neuroblastoma 2item
  25. Non-small Cell Lung Cancer 6item
  26. Ovarian Cancer 7item
  27. Pancreatic Cancer 11item
  28. Pancreatic Carcinoma 2item
  29. Prostate Cancer 14item
  30. Psoriasis 1 item
  31. Pulmonary Arterial Hypertension 1 item
  32. Pulmonary Fibrosis 1 item
  33. Renal Cancer 1 item
  34. Renal Cell Carcinoma 1 item
  35. Rheumatoid Arthritis 4item
  36. Thyroid Cancer 2item
  37. Type 2 Diabetes 2item