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Search results for: 'research area jak stat signaling egfr'

Search results for: 'research area jak stat signaling egfr'

A8219 Gefitinib (ZD1839)

3 Citation

Target: EGFR

Summary: Selective EGFR inhibitor

≥22.34 mg/mL
A1632 SB202190 (FHPI)

5 Citation

Target: p38

Summary: P38 MAPK inhibitor
A5566 LY2228820

1 Citation

Target: p38

Summary: P38 MAP kinase inhibitor

≥30.65 mg/mL
A3018 Trametinib (GSK1120212)

7 Citation

Target: MEK

Summary: MEK1 and MEK2 inhibitor, potent and selective

insoluble in H2O; insoluble in EtOH; ≥15.38 mg/mL
A3433 Gefitinib hydrochloride

Target: EGFR

Summary: Potent EGFR inhibitor

insoluble in EtOH; ≥4.28 mg/mL
A8346 BYL-719

1 Citation

Target: PI3K

Summary: Selective PI3Kα inhibitor

≥22.07 mg/mL
A8245 Sorafenib Tosylate

1 Citation

Target: Raf|VEGFR

Summary: Raf kinases and tyrosine kinases inhibitor

≥31.85 mg/mL
A8340 Cyclopamine

1 Citation

Target: Smoothened

Summary: Hedgehog (Hh) signaling Inhibitor

insoluble in EtOH; insoluble in H2O; ≥6.86 mg/mL
A3021 GDC-0449 (Vismodegib)

1 Citation

Target: P-glycoprotein (P-gp)|Hedgehog

Summary: Hedgehog antagonist,potent and selective

≥21.08 mg/mL
A8325 Tivantinib (ARQ 197)

2 Citation

Target: MET

Summary: C-Met inhibitor,non-ATP-competitive

≥18.47 mg/mL