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Search results for: 'research area jak stat signaling jak2'

Search results for: 'research area jak stat signaling jak2'

A3184 AR-A014418

2 Citation

Target: GSK-3

Summary: GSK3β inhibitor, ATP-competitive and selective

insoluble in EtOH; insoluble in H2O; ≥15.4 mg/mL
B5979 CCT251545

Summary: Orally bioavailable and potent WNT signaling inhibitor

≥42.2 mg/mL
A8340 Cyclopamine

1 Citation

Target: Smoothened

Summary: Hedgehog (Hh) signaling Inhibitor

insoluble in EtOH; insoluble in H2O; ≥6.86 mg/mL
A3021 GDC-0449 (Vismodegib)

1 Citation

Target: P-glycoprotein (P-gp)|Hedgehog

Summary: Hedgehog antagonist,potent and selective

≥21.08 mg/mL