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Search results for: 'research area jak stat signaling jak2'

Search results for: 'research area jak stat signaling jak2'

A3012 Ruxolitinib (INCB018424)

4 Citation

Target: JAK

Summary: JAK inhibitor

insoluble in H2O; ≥15.32 mg/mL
A3018 Trametinib (GSK1120212)

7 Citation

Target: MEK

Summary: MEK1 and MEK2 inhibitor, potent and selective

insoluble in H2O; insoluble in EtOH; ≥15.38 mg/mL
A8214 AZD8055

2 Citation

Target: mTOR

Summary: MTOR inhibitor

≥23.3 mg/mL
A8617 CCT128930 HCl

Target: Akt

Summary: AKT inhibitor

insoluble in H2O; ≥17.1 mg/mL
A3927 VS-5584 (SB2343)

Target: PI3K|mTOR

Summary: MTOR/P13K inhibitor,potent and selective

insoluble in H2O; ≥17.7 mg/mL
A1670 Enzastaurin (LY317615)

2 Citation

Target: PKC

Summary: PKC beta inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥8.59 mg/mL
A8245 Sorafenib Tosylate

1 Citation

Target: Raf|VEGFR

Summary: Raf kinases and tyrosine kinases inhibitor

≥31.85 mg/mL
B2283 Niclosamide

Target: STAT

Summary: Inhibitor of the STAT3 signaling pathway
A3433 Gefitinib hydrochloride

Target: EGFR

Summary: Potent EGFR inhibitor

insoluble in EtOH; ≥4.28 mg/mL
A3003 MDV3100 (Enzalutamide)

12 Citation

Target: Androgen Receptors

Summary: Androgen receptor antagonist

≥23.22 mg/mL