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  • Search results for: 'research area metabolism cyp3a cyp450'

Search results for: 'research area metabolism cyp3a cyp450'

Items 21-30 of 58

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  1. Lovastatin
    A4365 Lovastatin
    Target: HMG-CoA Reductases
    Summary: HMG-CoA reductase inhibitor
  2. Atorvastatin Calcium
    A4367 Atorvastatin Calcium
    Target: HMG-CoA Reductases
    Summary: HMG-CoA reductase inhibitor
      ≥57.75 mg/mL
  3. Pravastatin sodium
    A4369 Pravastatin sodium
    Target: HMG-CoA Reductases
    Summary: HMG-CoA reductase inhibitor,highly selective and competitive
  4. PF-3845
    A4374 PF-3845
     1 Citation
    Target: FAAH
    Summary: FAAH ihibitor,highly potent and selective
      Soluble in DMSO
  5. Canagliflozin
    A8333 Canagliflozin
     1 Citation
    Target: SGLT
    Summary: SGLT2 inhibitor,potent and selective
      ≥22.25 mg/mL
  6. Abiraterone acetate
    A8202 Abiraterone acetate
    Target: Cytochrome P450 (CYP450)
    Summary: Cytochrome p450 17a1 inhibitor
      insoluble in H2O; ≥11.22 mg/mL
  7. Rosiglitazone maleate
    A4302 Rosiglitazone maleate
    Target: Insulin and Insulin-like Receptors
    Summary: PPARγ agonist,high-affinity and selective,potent insulin sensitizer
      ≥23.7 mg/mL
  8. GSK3787
    A4303 GSK3787
    Summary: PPARβ/δ antagonist,novel and irreversible
      insoluble in H2O; ≥15.8 mg/mL
  9. Rosiglitazone
    A4304 Rosiglitazone
    Summary: Potent PPARγ agonist
      insoluble in EtOH; insoluble in H2O; ≥17.85 mg/mL
  10. Ketoconazole
    A4316 Ketoconazole
    Target: Cytochrome P450 (CYP450)
    Summary: Inhibitor of cyclosporine oxidase and testosterone 6 beta-hydroxylase
      ≥23.4 mg/mL

Items 21-30 of 58

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  1. Proteases 1 item
  2. Metabolism 51item
  3. DNA Damage/DNA Repair 1 item
  4. PI3K/Akt/mTOR Signaling 1 item
  5. Microbiology & Virology 1 item
  6. Stem Cell 1 item
  7. Membrane Transporter/Ion Channel 1 item
  8. Endocrinology and Hormones 1 item
  9. Neuroscience 2item
  10. Others 1 item
Specificity
  1. Selective 42item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 1 item
  2. Irreversible 4item
Target
  1. Acyl coenzyme A: cholesterol acyltransferases 1 item
  2. Factor Xa 1 item
  3. Phosphodiesterases (PDEs) 10item
  4. RARs 1 item
  5. Estrogen and Related Receptors 1 item
  6. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  7. AMPK 1 item
  8. Cytochrome P450 (CYP450) 4item
  9. HMG-CoA Reductases 3item
  10. SGLT 1 item
  11. DGAT 2item
  12. Insulin and Insulin-like Receptors 1 item
  13. Pyruvate dehydrogenases (PDH) 1 item
  14. CETP 2item
  15. Fatty-acid-binding proteins (FABPs) 1 item
  16. Folate Analogue 1 item
  17. Nampt 1 item
  18. Carbonic Anhydrases 3item
  19. Histamine H1 Receptors 1 item
  20. Phospholipases 1 item
  21. Catechol O-Methyltransferase (COMT) 1 item
  22. Hydroxylases 1 item
  23. ATGL 1 item
  24. FPTase 1 item
  25. PPAR 1 item
  26. FAAH 1 item
  27. carnitine reabsorption 1 item
  28. TRPC channel 1 item
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  31. Type 2 Diabetes 4item