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  • Search results for: 'research area metabolism cyp3a cyp450'

Search results for: 'research area metabolism cyp3a cyp450'

Items 61-70 of 238

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  1. Sildenafil Citrate
    A4321 Sildenafil Citrate
    Target: Phosphodiesterases (PDEs)
    Summary: Treat erectile dysfunction and PAH
      ≥25.35 mg/mL
  2. Tadalafil
    A4327 Tadalafil
    Target: Phosphodiesterases (PDEs)
    Summary: PDE5 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥16.6 mg/mL
  3. Rolipram
    A4328 Rolipram
    Target: Phosphodiesterases (PDEs)
    Summary: PDE4-inhibitor and an anti-inflammatory agent
      insoluble in H2O; ≥13 mg/mL
  4. CPI-613
    A4333 CPI-613
     1 Citation
    Target: Pyruvate dehydrogenases (PDH)
    Summary: PDH/α-KGDH inhibitor
      insoluble in H2O; ≥19.45 mg/mL
  5. AGI-5198
    A4339 AGI-5198
     1 Citation
    Summary: IDH1 inhibitor against R132 mutant,selective and cell-permeable
      ≥23.15 mg/mL
  6. S- (+)-Rolipram
    A4349 S- (+)-Rolipram
    Summary: CAMP-specific PDE4 inhibitor
      insoluble in H2O; ≥13.9 mg/mL
  7. Varespladib (LY315920)
    A4356 Varespladib (LY315920)
    Target: Phospholipases
    Summary: HnsPLA inhibitor,potent and selective
  8. JNJ-1661010
    A4361 JNJ-1661010
    Summary: FAAH inhibitor,potent and selective
      Soluble in DMSO
  9. Safinamide Mesylate
    A4368 Safinamide Mesylate
    Summary: MAO-B inhibitor,potent,selective and reversible
  10. Moclobemide (Ro 111163)
    A4370 Moclobemide (Ro 111163)
    Summary: Reversible inhibitor of MAO-A

Items 61-70 of 238

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  1. Signaling Pathways 126item
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  9. Peptides & Proteins 46item
  10. Protein & Immunology 1 item
Specificity
  1. Selective 47item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 1 item
  2. Irreversible 4item
Target
  1. Acyl coenzyme A: cholesterol acyltransferases 1 item
  2. Factor Xa 1 item
  3. Phosphodiesterases (PDEs) 10item
  4. RARs 1 item
  5. Trk Receptors 1 item
  6. Estrogen and Related Receptors 1 item
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  15. Insulin and Insulin-like Receptors 1 item
  16. Pyruvate dehydrogenases (PDH) 1 item
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  19. Folate Analogue 1 item
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