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Search results for: 'research area metabolism cyp3a cyp450'

Search results for: 'research area metabolism cyp3a cyp450'

A4322 Clarithromycin

Target: Cytochrome P450 (CYP450)

Summary: CYP3A inhibitor, potent

≥31.2 mg/mL
A4313 Cobicistat (GS-9350)

Target: Cytochrome P450 (CYP450)

Summary: Selective CYP3A inhibitor

insoluble in H2O; ≥150.9 mg/mL
A4329 Cilomilast

Target: Phosphodiesterases (PDEs)

Summary: Potent PDE4 inhibitor

insoluble in H2O; ≥12.95 mg/mL
A4373 NLG919

1 Citation

Summary: Potent IDO pathway inhibitor

insoluble in H2O; insoluble in EtOH; ≥47.7 mg/mL
A3552 Levomefolate calcium

Summary: Artificial form of folate

insoluble in EtOH; insoluble in DMSO; insoluble in H2O
A4300 GW9662

1 Citation

Summary: PPARγ antagonist

insoluble in H2O; ≥13.75 mg/mL
A4306 Ciprofibrate

Summary: PPARα agonist

insoluble in H2O; ≥10.85 mg/mL
A4309 GW501516

1 Citation

Summary: PPARδ agonist,selective and potent

insoluble in H2O; ≥18.05 mg/mL
A4318 Avasimibe

Target: Acyl coenzyme A: cholesterol acyltransferases

Summary: ACAT inhibitor,orally bioavailable

≥25.09 mg/mL
A4323 Vardenafil HCl Trihydrate

Target: Phosphodiesterases (PDEs)

Summary: PDE5 inhibitor, potent and selective

≥13.3 mg/mL