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  • Search results for: 'research area metabolism pde'

Search results for: 'research area metabolism pde'

Items 11-20 of 54

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  1. GW501516
    A4309 GW501516
     1 Citation
    Summary: PPARδ agonist,selective and potent
      insoluble in H2O; ≥18.05 mg/mL
  2. Avasimibe
    A4318 Avasimibe
    Target: Acyl coenzyme A: cholesterol acyltransferases
    Summary: ACAT inhibitor,orally bioavailable
      ≥25.09 mg/mL
  3. Clarithromycin
    A4322 Clarithromycin
    Target: Cytochrome P450 (CYP450)
    Summary: CYP3A inhibitor, potent
      ≥31.2 mg/mL
  4. Isotretinoin
    A4330 Isotretinoin
    Target: RARs
    Summary: Dopamine β-hydroxylase activator
      insoluble in H2O; ≥13.8 mg/mL
  5. Avanafil
    A4334 Avanafil
    Target: Phosphodiesterases (PDEs)
    Summary: PDE5 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥17.6 mg/mL
  6. Mildronate
    A4335 Mildronate
    Target: Hydroxylases|carnitine reabsorption
    Summary: GBB hydroxylase inhibitor
  7. Cilostazol
    A4337 Cilostazol
    Summary: PDE3 inhibitor
      insoluble in H2O; ≥15.4 mg/mL
  8. Pimobendan
    A4340 Pimobendan
    Target: Phosphodiesterases (PDEs)
    Summary: Selective PDE3 inhibitor.Ca2+ channel sensitizer
      insoluble in H2O; ≥16.2 mg/mL
  9. Tioxolone
    A4362 Tioxolone
    Target: Carbonic Anhydrases
    Summary: CAI inhibitor
      ≥63.2 mg/mL
  10. Lovastatin
    A4365 Lovastatin
    Target: HMG-CoA Reductases
    Summary: HMG-CoA reductase inhibitor

Items 11-20 of 54

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