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  • Search results for: 'research area pi3k akt signaling akt'

Search results for: 'research area pi3k akt signaling akt'

Items 41-50 of 97

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  1. Stattic
    A2224 Stattic
     5 Citation
    Target: STAT
    Summary: STAT3 inhibitor,small-molecule and potent
      insoluble in H2O; insoluble in EtOH; ≥10.56 mg/mL
  2. PLX-4720
    A3016 PLX-4720
     1 Citation
    Target: Raf
    Summary: BRAF kinase inhibitor
      ≥20.69 mg/mL
  3. SP 600125
    A4604 SP 600125
     7 Citation
    Target: JNK
    Summary: JNK1/2/3 inhibitor
      insoluble in H2O; ≥11 mg/mL
  4. Enzastaurin (LY317615)
    A1670 Enzastaurin (LY317615)
     2 Citation
    Target: PKC
    Summary: PKC beta inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥8.59 mg/mL
  5. BIX 02189
    A5801 BIX 02189
    Target: MEK|ERK
    Summary: Selective MEK5 inhibitor
      ≥22.05 mg/mL
  6. BIX 02188
    A5803 BIX 02188
    Target: MEK
    Summary: MEK5 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥10.3 mg/mL
  7. GF 109203X
    A8342 GF 109203X
     1 Citation
    Target: PKC
    Summary: Protein kinase C,MLCK,PKG and PKA inhibitor
      insoluble in EtOH; insoluble in H2O; ≥20.6 mg/mL
  8. RepSox
    A3754 RepSox
    Summary: ALK5 inhibitor,potent and selective
      insoluble in H2O; ≥14.35 mg/mL
  9. Vemurafenib (PLX4032, RG7204)
    A3004 Vemurafenib (PLX4032, RG7204)
     9 Citation
    Target: Raf
    Summary: BRAF kinase inhibitor
      ≥24.5 mg/mL
  10. NSC 74859
    A8338 NSC 74859
     5 Citation
    Target: STAT
    Summary: Stat3 inhibitor
      insoluble in H2O; ≥18.25 mg/mL

Items 41-50 of 97

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  1. Category Signaling Pathways Remove This Item
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Category
  1. Proteases 2item
  2. Apoptosis 1 item
  3. Chromatin/Epigenetics 4item
  4. Metabolism 3item
  5. MAPK Signaling 19item
  6. Tyrosine Kinase 9item
  7. DNA Damage/DNA Repair 6item
  8. PI3K/Akt/mTOR Signaling 36item
  9. Cell Cycle/Checkpoint 1 item
  10. Ubiquitination/ Proteasome 2item
  11. JAK/STAT Signaling 8item
  12. TGF-β / Smad Signaling 12item
  13. Stem Cell 13item
  14. Membrane Transporter/Ion Channel 1 item
  15. Endocrinology and Hormones 1 item
  16. Neuroscience 3item
  17. Obesity, Appetite Control & Diabetes 2item
  18. Other Signal Transduction 2item
  19. Immunology/Inflammation 1 item
  20. Cardiovascular 1 item
Reversibility
  1. Reversible 4item
  2. Irreversible 1 item
Target
  1. Histone Deacetylases (HDACs) 1 item
  2. Akt 5item
  3. PI3K 22item
  4. Raf 6item
  5. mTOR 10item
  6. Androgen Receptors 1 item
  7. GSK-3 5item
  8. P-glycoprotein (P-gp) 1 item
  9. PLK 1 item
  10. VEGFR 3item
  11. PDGFR 1 item
  12. Phosphodiesterases (PDEs) 1 item
  13. p38 4item
  14. PKB 1 item
  15. JNK 4item
  16. MEK 5item
  17. PORCN 1 item
  18. FGFR 1 item
  19. GABAB Receptors 1 item
  20. Smoothened 1 item
  21. STAT 4item
  22. EGFR 2item
  23. Hedgehog 1 item
  24. BMP and Other Activin Receptors 2item
  25. JAK 2item
  26. Syk 1 item
  27. DNA-PK 4item
  28. HSP90 1 item
  29. TNKS 1 item
  30. Toll-like receptors (TLRs) 1 item
  31. ERK 1 item
  32. PKC 3item
  33. Melanocortin (MC) Receptors 1 item
  34. Fatty-acid-binding proteins (FABPs) 1 item
  35. NO Donors / Precursors 1 item
  36. IL Receptors 1 item
  37. PKD 1 item
  38. ATM 1 item
Reported Experiments
  1. Animal Experiments 90item
  2. Cell Experiments 56item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 2item
  3. Bladder Cancer 1 item
  4. Breast Cancer 23item
  5. Cancer 64item
  6. Cervical Cancer 2item
  7. Cholangiocarcinoma 1 item
  8. Chronic Lymphocytic Leukemia 1 item
  9. Colon Cancer 10item
  10. Colon Carcinoma 1 item
  11. Colorectal Cancer 11item
  12. Glioblastoma 10item
  13. Glioma 4item
  14. Hepatocellular Carcinoma 1 item
  15. Leukemia 5item
  16. Liver Cancer 1 item
  17. Lung Cancer 7item
  18. Lymphoma 2item
  19. Melanoma 6item
  20. Multiple Myeloma 1 item
  21. Myeloma 1 item
  22. Neuroblastoma 2item
  23. Non-small Cell Lung Cancer 6item
  24. Ovarian Cancer 7item
  25. Pancreatic Cancer 9item
  26. Pancreatic Carcinoma 2item
  27. Prostate Cancer 11item
  28. Pulmonary Arterial Hypertension 1 item
  29. Pulmonary Fibrosis 1 item
  30. Renal Cancer 2item
  31. Rheumatoid Arthritis 2item
  32. Thyroid Cancer 2item
  33. Type 2 Diabetes 2item