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  • Search results for: 'research area pi3k akt signaling akt'

Search results for: 'research area pi3k akt signaling akt'

Items 71-80 of 307

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  1. LDN-193189
    A8324 LDN-193189
    Target: BMP and Other Activin Receptors
    Summary: ALK inhibitor,potent and selective
      insoluble in DMSO; insoluble in EtOH; insoluble in H2O
  2. LY2940680
    A8651 LY2940680
    Target: Smoothened receptor
    Summary: Hedgehog/SMO antagonist,inhibits Hh signaling
  3. JW 55
    A4529 JW 55
    Summary: PARP domain inhibitor
      insoluble in H2O; ≥19.25 mg/mL
  4. LDN193189 Hydrochloride
    A3545 LDN193189 Hydrochloride
     1 Citation
    Summary: ALK inhibitor,potent and selective
      ≥27.6 mg/mL
  5. SB-505124 hydrochloride
    A3799 SB-505124 hydrochloride
    Target: ALK
    Summary: ALK5/ALK4/ALK7 inhibitor in TGF-β/activin signalling,selective
  6. TAK-632
    A8226 TAK-632
    Target: Raf
    Summary: Pan-RAF inhibitor,potent and selective
      ≥27.75 mg/mL
  7. AZD6244 (Selumetinib)
    A8207 AZD6244 (Selumetinib)
     3 Citation
    Summary: MEK inhibitor
      ≥22.88 mg/mL
  8. GDC-0879
    A5071 GDC-0879
     1 Citation
    Target: Raf
    Summary: B-Raf inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥16.7 mg/mL
  9. PD184352 (CI-1040)
    A1792 PD184352 (CI-1040)
    Target: MEK
    Summary: Selective MEK inhibitor
      ≥47.9 mg/mL
  10. SB202190 (FHPI)
    A1632 SB202190 (FHPI)
     5 Citation
    Target: p38
    Summary: P38 MAPK inhibitor

Items 71-80 of 307

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Category
  1. Proteases 4item
  2. Apoptosis 10item
  3. Chromatin/Epigenetics 10item
  4. Metabolism 5item
  5. MAPK Signaling 34item
  6. Tyrosine Kinase 16item
  7. DNA Damage/DNA Repair 11item
  8. PI3K/Akt/mTOR Signaling 103item
  9. Microbiology & Virology 1 item
  10. Cell Cycle/Checkpoint 7item
  11. Ubiquitination/ Proteasome 4item
  12. JAK/STAT Signaling 13item
  13. TGF-β / Smad Signaling 22item
  14. GPCR/G protein 3item
  15. Stem Cell 38item
  16. Membrane Transporter/Ion Channel 3item
  17. Cancer Biology 12item
  18. Endocrinology and Hormones 16item
  19. Neuroscience 17item
  20. Obesity, Appetite Control & Diabetes 4item
  21. Other Signal Transduction 42item
  22. Others 14item
  23. Immunology/Inflammation 8item
  24. Cardiovascular 24item
Specificity
  1. Selective 97item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 8item
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 12item
  4. PI3K 30item
  5. Raf 8item
  6. Aurora Kinases 1 item
  7. mTOR 15item
  8. Androgen Receptors 1 item
  9. FLT3 1 item
  10. GSK-3 7item
  11. P-glycoprotein (P-gp) 1 item
  12. PLK 1 item
  13. VEGFR 5item
  14. PDGFR 1 item
  15. Phosphodiesterases (PDEs) 1 item
  16. p38 4item
  17. PKB 1 item
  18. JNK 4item
  19. MEK 5item
  20. PORCN 1 item
  21. FGFR 1 item
  22. GABAB Receptors 1 item
  23. Smoothened 1 item
  24. NMDA Receptors 1 item
  25. STAT 6item
  26. EGFR 2item
  27. Hedgehog 1 item
  28. BMP and Other Activin Receptors 2item
  29. JAK 3item
  30. Syk 1 item
  31. DNA-PK 5item
  32. HSP90 1 item
  33. TNKS 1 item
  34. Toll-like receptors (TLRs) 1 item
  35. ERK 2item
  36. PKC 6item
  37. Melanocortin (MC) Receptors 1 item
  38. ALK 1 item
  39. PKG 1 item
  40. PKA 4item
  41. Fatty-acid-binding proteins (FABPs) 1 item
  42. RSK 1 item
  43. Histamine H1 Receptors 1 item
  44. NO Donors / Precursors 1 item
  45. IL Receptors 1 item
  46. AChE 1 item
  47. BACE 1 item
  48. p70 rsk 1 item
  49. sodium channels 1 item
  50. Smoothened receptor 1 item
  51. Nrf2/ARE signal 1 item
  52. PPAR 1 item
  53. Antibiotic 1 item
  54. Prk 1 item
  55. ICAM 1 item
  56. Rho 1 item
  57. Thrombin Receptor 1 item
  58. prolactin secretion 1 item
  59. gonadotropin release 1 item
  60. TRPC channel 1 item
  61. PKD 1 item
  62. FKBP 1 item
  63. ATM 1 item
Reported Experiments
  1. Animal Experiments 132item
  2. Cell Experiments 103item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 2item
  3. Bladder Cancer 1 item
  4. Breast Cancer 24item
  5. Cancer 85item
  6. Cervical Cancer 2item
  7. Cholangiocarcinoma 1 item
  8. Chronic Lymphocytic Leukemia 1 item
  9. Colon Cancer 10item
  10. Colon Carcinoma 1 item
  11. Colorectal Cancer 11item
  12. Glioblastoma 10item
  13. Glioma 4item
  14. Heart Failure 1 item
  15. Hepatocellular Carcinoma 1 item
  16. Leukemia 6item
  17. Liver Cancer 1 item
  18. Lung Cancer 7item
  19. Lymphoma 2item
  20. Melanoma 7item
  21. Multiple Myeloma 1 item
  22. Myeloma 1 item
  23. Neuroblastoma 2item
  24. Non-small Cell Lung Cancer 6item
  25. Ovarian Cancer 7item
  26. Pancreatic Cancer 9item
  27. Pancreatic Carcinoma 2item
  28. Prostate Cancer 11item
  29. Pulmonary Arterial Hypertension 1 item
  30. Pulmonary Fibrosis 1 item
  31. Renal Cancer 2item
  32. Rheumatoid Arthritis 2item
  33. Thyroid Cancer 2item
  34. Type 2 Diabetes 2item