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  • Search results for: 'research area pi3k akt signaling akt'

Search results for: 'research area pi3k akt signaling akt'

Items 121-130 of 132

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  1. NLG919
    A4373 NLG919
     1 Citation
    Summary: Potent IDO pathway inhibitor
      insoluble in H2O; insoluble in EtOH; ≥47.7 mg/mL
  2. Methimazole
    A8472 Methimazole
    Target: ICAM
    Summary: ICAM-1 inhibitor
      ≥49.1 mg/mL
  3. GDC-0449 (Vismodegib)
    A3021 GDC-0449 (Vismodegib)
     1 Citation
    Target: P-glycoprotein (P-gp)|Hedgehog
    Summary: Hedgehog antagonist,potent and selective
      ≥21.08 mg/mL
  4. NU 7026
    A8649 NU 7026
    Target: PI3K|DNA-PK|ATM
    Summary: DNPK inhibitor,ATP-competitive and potent
      insoluble in EtOH; insoluble in DMSO; insoluble in H2O
  5. WYE-125132 (WYE-132)
    B1642 WYE-125132 (WYE-132)
    Target: mTOR
    Summary: ATP-competitive mTOR inhibitor, highly potent
      insoluble in EtOH; insoluble in H2O; ≥13 mg/mL
  6. NU7441 (KU-57788)
    A8315 NU7441 (KU-57788)
     4 Citation
    Target: PI3K|DNA-PK
    Summary: DNA-PK inhibitor
      insoluble in EtOH; insoluble in H2O; ≥4.13 mg/mL
  7. (-)-Huperzine A
    A1932 (-)-Huperzine A
    Target: NMDA Receptors|AChE
    Summary: NMDA receptor antagonist/AChE inhibitor
      insoluble in H2O; ≥12.12 mg/mL
  8. GDC-0032
    B1047 GDC-0032
    Target: PI3K
    Summary: PI3Kα inhibitor
      ≥23.05 mg/mL
  9. Tofacitinib (CP-690550) Citrate
    A4135 Tofacitinib (CP-690550) Citrate
     2 Citation
    Target: JAK
    Summary: Potent JAK inhibitor
      ≥25.22 mg/mL
  10. Afatinib (BIBW2992)
    A8247 Afatinib (BIBW2992)
     1 Citation
    Target: EGFR
    Summary: Irreversible EGFR/HER2 inhibitor
      ≥24.3 mg/mL

Items 121-130 of 132

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Category
  1. Natural Products 1 item
Specificity
  1. Selective 90item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 7item
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 12item
  4. PI3K 29item
  5. Raf 8item
  6. Aurora Kinases 1 item
  7. mTOR 15item
  8. Androgen Receptors 1 item
  9. FLT3 1 item
  10. GSK-3 6item
  11. P-glycoprotein (P-gp) 1 item
  12. PLK 1 item
  13. VEGFR 5item
  14. PDGFR 1 item
  15. Phosphodiesterases (PDEs) 1 item
  16. p38 4item
  17. PKB 1 item
  18. JNK 2item
  19. MEK 4item
  20. PORCN 1 item
  21. FGFR 1 item
  22. GABAB Receptors 1 item
  23. Smoothened 1 item
  24. NMDA Receptors 1 item
  25. STAT 6item
  26. EGFR 2item
  27. Hedgehog 1 item
  28. BMP and Other Activin Receptors 2item
  29. JAK 3item
  30. Syk 1 item
  31. DNA-PK 5item
  32. HSP90 1 item
  33. TNKS 1 item
  34. Toll-like receptors (TLRs) 1 item
  35. ERK 2item
  36. PKC 6item
  37. Melanocortin (MC) Receptors 1 item
  38. ALK 1 item
  39. PKG 1 item
  40. PKA 4item
  41. Fatty-acid-binding proteins (FABPs) 1 item
  42. RSK 1 item
  43. Histamine H1 Receptors 1 item
  44. NO Donors / Precursors 1 item
  45. IL Receptors 1 item
  46. AChE 1 item
  47. BACE 1 item
  48. p70 rsk 1 item
  49. Smoothened receptor 1 item
  50. Antibiotic 1 item
  51. Prk 1 item
  52. ICAM 1 item
  53. Rho 1 item
  54. Thrombin Receptor 1 item
  55. prolactin secretion 1 item
  56. gonadotropin release 1 item
  57. TRPC channel 1 item
  58. PKD 1 item
  59. FKBP 1 item
  60. ATM 1 item
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  3. Bladder Cancer 1 item
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  7. Cholangiocarcinoma 1 item
  8. Chronic Lymphocytic Leukemia 1 item
  9. Colon Cancer 10item
  10. Colon Carcinoma 1 item
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  25. Ovarian Cancer 7item
  26. Pancreatic Cancer 9item
  27. Pancreatic Carcinoma 2item
  28. Prostate Cancer 11item
  29. Pulmonary Arterial Hypertension 1 item
  30. Pulmonary Fibrosis 1 item
  31. Renal Cancer 2item
  32. Rheumatoid Arthritis 2item
  33. Thyroid Cancer 2item
  34. Type 2 Diabetes 2item