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  • Search results for: 'research area pi3k akt signaling gsk'

Search results for: 'research area pi3k akt signaling gsk'

Items 131-140 of 143

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  1. Methimazole
    A8472 Methimazole
    Target: ICAM
    Summary: ICAM-1 inhibitor
      ≥49.1 mg/mL
  2. CHIR-124
    A8394 CHIR-124
    Target: FLT3|GSK-3|Chk|PDGFR
    Summary: Chk1 inhibitor,novel and potent
      insoluble in H2O; ≥10.5 mg/mL
  3. GDC-0449 (Vismodegib)
    A3021 GDC-0449 (Vismodegib)
     1 Citation
    Target: P-glycoprotein (P-gp)|Hedgehog
    Summary: Hedgehog antagonist,potent and selective
      ≥21.08 mg/mL
  4. NU 7026
    A8649 NU 7026
    Target: PI3K|DNA-PK|ATM
    Summary: DNPK inhibitor,ATP-competitive and potent
      insoluble in EtOH; insoluble in DMSO; insoluble in H2O
  5. WYE-125132 (WYE-132)
    B1642 WYE-125132 (WYE-132)
    Target: mTOR
    Summary: ATP-competitive mTOR inhibitor, highly potent
      insoluble in EtOH; insoluble in H2O; ≥13 mg/mL
  6. NU7441 (KU-57788)
    A8315 NU7441 (KU-57788)
     4 Citation
    Target: PI3K|DNA-PK
    Summary: DNA-PK inhibitor
      insoluble in EtOH; insoluble in H2O; ≥4.13 mg/mL
  7. KU-0060648
    A1769 KU-0060648
     1 Citation
    Target: PI3K|DNA-PK
    Summary: Dual DNA-PK/PI3-K inhibitor, ATP-competitive
  8. (-)-Huperzine A
    A1932 (-)-Huperzine A
    Target: NMDA Receptors|AChE
    Summary: NMDA receptor antagonist/AChE inhibitor
      insoluble in H2O; ≥12.12 mg/mL
  9. GDC-0032
    B1047 GDC-0032
    Target: PI3K
    Summary: PI3Kα inhibitor
      ≥23.05 mg/mL
  10. Tofacitinib (CP-690550) Citrate
    A4135 Tofacitinib (CP-690550) Citrate
     2 Citation
    Target: JAK
    Summary: Potent JAK inhibitor
      ≥25.22 mg/mL

Items 131-140 of 143

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Category
  1. Proteases 3item
  2. Apoptosis 3item
  3. Chromatin/Epigenetics 6item
  4. Metabolism 5item
  5. MAPK Signaling 19item
  6. Tyrosine Kinase 10item
  7. DNA Damage/DNA Repair 8item
  8. PI3K/Akt/mTOR Signaling 53item
  9. Cell Cycle/Checkpoint 6item
  10. Ubiquitination/ Proteasome 2item
  11. JAK/STAT Signaling 10item
  12. TGF-β / Smad Signaling 14item
  13. GPCR/G protein 1 item
  14. Stem Cell 17item
  15. Membrane Transporter/Ion Channel 2item
  16. Cancer Biology 1 item
  17. Endocrinology and Hormones 2item
  18. Neuroscience 8item
  19. Obesity, Appetite Control & Diabetes 2item
  20. Other Signal Transduction 6item
  21. Others 3item
  22. Immunology/Inflammation 1 item
  23. Cardiovascular 5item
Specificity
  1. Selective 100item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 7item
  2. Irreversible 2item
Target
  1. Cyclin-Dependent Kinases 3item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 12item
  4. PI3K 29item
  5. Raf 8item
  6. Aurora Kinases 1 item
  7. EZH2 1 item
  8. mTOR 15item
  9. Androgen Receptors 1 item
  10. FLT3 2item
  11. GSK-3 10item
  12. P-glycoprotein (P-gp) 1 item
  13. PLK 1 item
  14. Chk 1 item
  15. VEGFR 5item
  16. PDGFR 2item
  17. Phosphodiesterases (PDEs) 1 item
  18. p38 4item
  19. PKB 1 item
  20. JNK 2item
  21. MEK 5item
  22. PORCN 1 item
  23. FGFR 1 item
  24. GABAB Receptors 1 item
  25. Smoothened 1 item
  26. NMDA Receptors 1 item
  27. STAT 6item
  28. EGFR 2item
  29. Hedgehog 1 item
  30. BMP and Other Activin Receptors 2item
  31. JAK 3item
  32. Syk 1 item
  33. DNA-PK 5item
  34. HSP90 1 item
  35. TNKS 1 item
  36. Toll-like receptors (TLRs) 1 item
  37. ERK 2item
  38. PKC 6item
  39. Melanocortin (MC) Receptors 1 item
  40. ALK 1 item
  41. PKG 1 item
  42. PKA 4item
  43. Fatty-acid-binding proteins (FABPs) 1 item
  44. RSK 1 item
  45. Free Fatty Acid Receptors 1 item
  46. Histamine H1 Receptors 1 item
  47. NO Donors / Precursors 1 item
  48. IL Receptors 1 item
  49. AChE 1 item
  50. BACE 1 item
  51. p70 rsk 1 item
  52. Smoothened receptor 1 item
  53. Antibiotic 1 item
  54. Rev-Erb Receptors 1 item
  55. Prk 1 item
  56. ICAM 1 item
  57. Rho 1 item
  58. Thrombin Receptor 1 item
  59. prolactin secretion 1 item
  60. gonadotropin release 1 item
  61. TRPC channel 1 item
  62. PKD 1 item
  63. FKBP 1 item
  64. ATM 1 item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 2item
  3. Bladder Cancer 1 item
  4. Breast Cancer 24item
  5. Cancer 90item
  6. Cervical Cancer 2item
  7. Cholangiocarcinoma 1 item
  8. Chronic Lymphocytic Leukemia 1 item
  9. Colon Cancer 10item
  10. Colon Carcinoma 1 item
  11. Colorectal Cancer 11item
  12. Diabetes 1 item
  13. Glioblastoma 11item
  14. Glioma 4item
  15. Heart Failure 1 item
  16. Hepatocellular Carcinoma 1 item
  17. Leukemia 6item
  18. Liver Cancer 1 item
  19. Lung Cancer 8item
  20. Lymphoma 2item
  21. Melanoma 8item
  22. Multiple Myeloma 1 item
  23. Myeloma 1 item
  24. Neuroblastoma 2item
  25. Non-small Cell Lung Cancer 6item
  26. Ovarian Cancer 8item
  27. Pancreatic Cancer 9item
  28. Pancreatic Carcinoma 2item
  29. Prostate Cancer 11item
  30. Pulmonary Arterial Hypertension 1 item
  31. Pulmonary Fibrosis 1 item
  32. Renal Cancer 2item
  33. Rheumatoid Arthritis 2item
  34. Thyroid Cancer 2item
  35. Type 2 Diabetes 2item