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  • Search results for: 'research area pi3k akt signaling gsk'

Search results for: 'research area pi3k akt signaling gsk'

Items 351-360 of 366

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  1. WYE-125132 (WYE-132)
    B1642 WYE-125132 (WYE-132)
    Target: mTOR
    Summary: ATP-competitive mTOR inhibitor, highly potent
      insoluble in EtOH; insoluble in H2O; ≥13 mg/mL
  2. Pluripotin
    B5593 Pluripotin
    Summary: dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP
      ≥119 mg/mL
  3. NU7441 (KU-57788)
    A8315 NU7441 (KU-57788)
     4 Citation
    Target: PI3K|DNA-PK
    Summary: DNA-PK inhibitor
      insoluble in EtOH; insoluble in H2O; ≥4.13 mg/mL
  4. TCS 21311
    A4516 TCS 21311
    Summary: JAK3 inhibitor
      <52.65 mg/mL
  5. KU-0060648
    A1769 KU-0060648
     1 Citation
    Target: PI3K|DNA-PK
    Summary: Dual DNA-PK/PI3-K inhibitor, ATP-competitive
  6. (-)-Huperzine A
    A1932 (-)-Huperzine A
    Target: NMDA Receptors|AChE
    Summary: NMDA receptor antagonist/AChE inhibitor
      insoluble in H2O; ≥12.12 mg/mL
  7. GDC-0032
    B1047 GDC-0032
    Target: PI3K
    Summary: PI3Kα inhibitor
      ≥23.05 mg/mL
  8. Tofacitinib (CP-690550) Citrate
    A4135 Tofacitinib (CP-690550) Citrate
     2 Citation
    Target: JAK
    Summary: Potent JAK inhibitor
      ≥25.22 mg/mL
  9. Adenosine-5'-diphosphate
    C4341 Adenosine-5'-diphosphate
    Summary: central component of energy storage, metabolism, and signal transduction in vivo;agonist of purinergic receptors
      ≥21.35 mg/mL
  10. KU 55933
    A4605 KU 55933
     1 Citation
    Summary: ATM inhibitor,potent and selective
      ≥41.67 mg/mL

Items 351-360 of 366

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Category
  1. Proteases 6item
  2. Apoptosis 11item
  3. Chromatin/Epigenetics 20item
  4. Metabolism 9item
  5. MAPK Signaling 36item
  6. Tyrosine Kinase 16item
  7. DNA Damage/DNA Repair 11item
  8. PI3K/Akt/mTOR Signaling 113item
  9. Microbiology & Virology 2item
  10. Cell Cycle/Checkpoint 12item
  11. Ubiquitination/ Proteasome 4item
  12. JAK/STAT Signaling 14item
  13. TGF-β / Smad Signaling 22item
  14. GPCR/G protein 8item
  15. Stem Cell 55item
  16. Membrane Transporter/Ion Channel 4item
  17. Cancer Biology 12item
  18. Endocrinology and Hormones 17item
  19. Neuroscience 20item
  20. Obesity, Appetite Control & Diabetes 4item
  21. Other Signal Transduction 42item
  22. Others 18item
  23. Immunology/Inflammation 8item
  24. Cardiovascular 24item
Specificity
  1. Selective 110item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 8item
  2. Irreversible 2item
Target
  1. Cyclin-Dependent Kinases 3item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 12item
  4. PI3K 30item
  5. Raf 8item
  6. Aurora Kinases 1 item
  7. EZH2 2item
  8. mTOR 15item
  9. Androgen Receptors 1 item
  10. FLT3 2item
  11. GSK-3 11item
  12. P-glycoprotein (P-gp) 1 item
  13. PLK 1 item
  14. Chk 1 item
  15. VEGFR 5item
  16. PDGFR 2item
  17. Phosphodiesterases (PDEs) 1 item
  18. p38 4item
  19. PKB 1 item
  20. JNK 4item
  21. SGK 1 item
  22. MEK 6item
  23. PORCN 1 item
  24. FGFR 1 item
  25. GABAB Receptors 1 item
  26. Smoothened 1 item
  27. NMDA Receptors 1 item
  28. STAT 6item
  29. EGFR 2item
  30. Hedgehog 1 item
  31. BMP and Other Activin Receptors 2item
  32. JAK 3item
  33. Syk 1 item
  34. DNA-PK 5item
  35. HSP90 1 item
  36. TNKS 1 item
  37. Toll-like receptors (TLRs) 1 item
  38. ERK 2item
  39. PKC 6item
  40. Melanocortin (MC) Receptors 1 item
  41. ALK 1 item
  42. PKG 1 item
  43. PKA 4item
  44. Lactate Dehydrogenases (LDH) 1 item
  45. Fatty-acid-binding proteins (FABPs) 1 item
  46. RSK 1 item
  47. Free Fatty Acid Receptors 1 item
  48. Histamine H1 Receptors 1 item
  49. NO Donors / Precursors 1 item
  50. IL Receptors 1 item
  51. AChE 1 item
  52. BACE 1 item
  53. p70 rsk 1 item
  54. sodium channels 1 item
  55. Smoothened receptor 1 item
  56. Nrf2/ARE signal 1 item
  57. PPAR 1 item
  58. Antibiotic 1 item
  59. Rev-Erb Receptors 1 item
  60. Prk 1 item
  61. ICAM 1 item
  62. Rho 1 item
  63. Thrombin Receptor 1 item
  64. prolactin secretion 1 item
  65. gonadotropin release 1 item
  66. TRPC channel 1 item
  67. PKD 1 item
  68. FKBP 1 item
  69. ATM 1 item
Reported Experiments
  1. Animal Experiments 143item
  2. Cell Experiments 112item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 2item
  3. Bladder Cancer 1 item
  4. Breast Cancer 25item
  5. Cancer 92item
  6. Cervical Cancer 2item
  7. Cholangiocarcinoma 1 item
  8. Chronic Lymphocytic Leukemia 1 item
  9. Colon Cancer 10item
  10. Colon Carcinoma 1 item
  11. Colorectal Cancer 11item
  12. Diabetes 1 item
  13. Glioblastoma 11item
  14. Glioma 4item
  15. Heart Failure 1 item
  16. Hepatocellular Carcinoma 1 item
  17. Leukemia 6item
  18. Liver Cancer 1 item
  19. Lung Cancer 8item
  20. Lymphoma 2item
  21. Melanoma 8item
  22. Multiple Myeloma 1 item
  23. Myeloma 1 item
  24. Neuroblastoma 2item
  25. Non-small Cell Lung Cancer 6item
  26. Ovarian Cancer 8item
  27. Pancreatic Cancer 9item
  28. Pancreatic Carcinoma 2item
  29. Prostate Cancer 13item
  30. Pulmonary Arterial Hypertension 1 item
  31. Pulmonary Fibrosis 1 item
  32. Renal Cancer 2item
  33. Rheumatoid Arthritis 2item
  34. Thyroid Cancer 2item
  35. Type 2 Diabetes 2item