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  • Search results for: 'research area pi3k akt signaling gsk'

Search results for: 'research area pi3k akt signaling gsk'

Items 1-10 of 112

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  1. AKT inhibitor VIII
    A3149 AKT inhibitor VIII
     2 Citation
    Target: Akt
    Summary: Allosteric Akt kinase inhibitor
      insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL
  2. Dabrafenib Mesylate (GSK-2118436)
    A3347 Dabrafenib Mesylate (GSK-2118436)
    Target: Raf
    Summary: Inhibitor of BRAF(V600) mutants
      ≥30.75 mg/mL
  3. CHIR-99021 (CT99021)
    A3011 CHIR-99021 (CT99021)
     2 Citation
    Target: GSK-3
    Summary: GSK-3 inhibitor, Cell-permeable, ATP-competitive
      ≥23.27 mg/mL
  4. LY2090314
    A3570 LY2090314
    Target: GSK-3
    Summary: Potent GSK-3 inhibitor
      insoluble in H2O; ≥91 mg/mL
  5. AR-A014418
    A3184 AR-A014418
     2 Citation
    Target: GSK-3
    Summary: GSK3β inhibitor, ATP-competitive and selective
      insoluble in EtOH; insoluble in H2O; ≥15.4 mg/mL
  6. SB 216763
    A8240 SB 216763
     3 Citation
    Target: GSK-3
    Summary: GSK-3 inhibitor,ATP-competitive,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥56.8 mg/mL
  7. CHIR-99021 (CT99021) HCl
    A8396 CHIR-99021 (CT99021) HCl
    Target: GSK-3
    Summary: GSK-3α/β inhibitor
      ≥25.1 mg/mL
  8. GDC-0068 (RG7440)
    A3006 GDC-0068 (RG7440)
    Target: Akt
    Summary: Pan-AKT inhibitor,highly selective
      ≥22.9 mg/mL
  9. CCT128930 HCl
    A8617 CCT128930 HCl
    Target: Akt
    Summary: AKT inhibitor
      insoluble in H2O; ≥17.1 mg/mL
  10. BKM120
    A3015 BKM120
     1 Citation
    Target: PI3K
    Summary: Inhibitor of pan-Class I PI3K
      ≥20.52 mg/mL

Items 1-10 of 112

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Category
  1. Signaling Pathways 110item
  2. Peptides 1 item
  3. Peptides & Proteins 1 item
Reversibility
  1. Reversible 4item
  2. Irreversible 2item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 5item
  4. PI3K 22item
  5. Raf 6item
  6. EZH2 2item
  7. mTOR 10item
  8. Androgen Receptors 1 item
  9. FLT3 1 item
  10. GSK-3 9item
  11. P-glycoprotein (P-gp) 1 item
  12. PLK 1 item
  13. Chk 1 item
  14. VEGFR 3item
  15. PDGFR 2item
  16. Phosphodiesterases (PDEs) 1 item
  17. p38 4item
  18. PKB 1 item
  19. JNK 4item
  20. SGK 1 item
  21. MEK 6item
  22. PORCN 1 item
  23. FGFR 1 item
  24. GABAB Receptors 1 item
  25. Smoothened 1 item
  26. Trk Receptors 1 item
  27. STAT 4item
  28. EGFR 2item
  29. Hedgehog 1 item
  30. BMP and Other Activin Receptors 2item
  31. JAK 2item
  32. Syk 1 item
  33. DNA-PK 4item
  34. HSP90 1 item
  35. TNKS 1 item
  36. Toll-like receptors (TLRs) 1 item
  37. ERK 1 item
  38. PKC 3item
  39. Melanocortin (MC) Receptors 1 item
  40. Lactate Dehydrogenases (LDH) 1 item
  41. Fatty-acid-binding proteins (FABPs) 1 item
  42. Free Fatty Acid Receptors 1 item
  43. NO Donors / Precursors 1 item
  44. IL Receptors 1 item
  45. Rev-Erb Receptors 1 item
  46. PKD 1 item
  47. ATM 1 item
Reported Experiments
  1. Animal Experiments 100item
  2. Cell Experiments 64item
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  2. Acute Myeloid Leukemia 2item
  3. Bladder Cancer 1 item
  4. Breast Cancer 24item
  5. Cancer 70item
  6. Cervical Cancer 2item
  7. Cholangiocarcinoma 1 item
  8. Chronic Lymphocytic Leukemia 1 item
  9. Colon Cancer 10item
  10. Colon Carcinoma 1 item
  11. Colorectal Cancer 11item
  12. Diabetes 1 item
  13. Glioblastoma 11item
  14. Glioma 4item
  15. Hepatocellular Carcinoma 1 item
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  18. Lung Cancer 8item
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  20. Melanoma 7item
  21. Multiple Myeloma 1 item
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  24. Non-small Cell Lung Cancer 6item
  25. Ovarian Cancer 8item
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  28. Prostate Cancer 13item
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  34. Type 2 Diabetes 2item