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  • Search results for: 'research area pi3k akt signaling mtor signaling'

Search results for: 'research area pi3k akt signaling mtor signaling'

Items 21-30 of 321

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  1. GDC-0068 (RG7440)
    A3006 GDC-0068 (RG7440)
    Target: Akt
    Summary: Pan-AKT inhibitor,highly selective
      ≥22.9 mg/mL
  2. CCT128930 HCl
    A8617 CCT128930 HCl
    Target: Akt
    Summary: AKT inhibitor
      insoluble in H2O; ≥17.1 mg/mL
  3. PIK-90
    A2764 PIK-90
    Summary: PI3K inhibitor,potent selective
      insoluble in DMSO
  4. BKM120
    A3015 BKM120
     1 Citation
    Target: PI3K
    Summary: Inhibitor of pan-Class I PI3K
      ≥20.52 mg/mL
  5. A-443654
    A3135 A-443654
    Summary: Akt inhibitor,potent and selective
      insoluble in H2O; ≥19.85 mg/mL
  6. NVP-BKM120 Hydrochloride
    A3674 NVP-BKM120 Hydrochloride
    Summary: PI3K inhibitor
      ≥44.7 mg/mL
  7. XL147
    A5112 XL147
    Target: PI3K
    Summary: PI3K inhibitor,selective and reversible
      ≥22.45 mg/mL
  8. PIK-75
    A2080 PIK-75
    Summary: Inhibitor of PI3K isoform p110α
      insoluble in H2O; insoluble in EtOH; ≥8.15 mg/mL
  9. KU-0063794
    A5078 KU-0063794
    Target: mTOR
    Summary: MTORC1 and mTORC2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥11.65 mg/mL
  10. GSK690693
    A5072 GSK690693
    Target: Akt|PKC|PKG|PKA|Prk
    Summary: Pan-AKT inhibitor,ATP-competitive and potent
      ≥21.25 mg/mL

Items 21-30 of 321

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  1. Proteases 4item
  2. Apoptosis 10item
  3. Chromatin/Epigenetics 10item
  4. Metabolism 5item
  5. MAPK Signaling 34item
  6. Tyrosine Kinase 16item
  7. DNA Damage/DNA Repair 14item
  8. PI3K/Akt/mTOR Signaling 115item
  9. Microbiology & Virology 1 item
  10. Cell Cycle/Checkpoint 8item
  11. Ubiquitination/ Proteasome 4item
  12. JAK/STAT Signaling 13item
  13. TGF-β / Smad Signaling 22item
  14. GPCR/G protein 3item
  15. Stem Cell 38item
  16. Membrane Transporter/Ion Channel 3item
  17. Cancer Biology 12item
  18. Endocrinology and Hormones 16item
  19. Neuroscience 17item
  20. Obesity, Appetite Control & Diabetes 4item
  21. Other Signal Transduction 42item
  22. Others 14item
  23. Immunology/Inflammation 8item
  24. Cardiovascular 24item
Specificity
  1. Selective 102item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 8item
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 12item
  4. PI3K 31item
  5. Raf 8item
  6. Aurora Kinases 1 item
  7. mTOR 22item
  8. Androgen Receptors 1 item
  9. FLT3 1 item
  10. GSK-3 7item
  11. P-glycoprotein (P-gp) 1 item
  12. PLK 1 item
  13. Eph Receptors 1 item
  14. VEGFR 6item
  15. PDGFR 2item
  16. Phosphodiesterases (PDEs) 1 item
  17. p38 4item
  18. PKB 1 item
  19. JNK 4item
  20. Bcr-Abl 1 item
  21. MEK 5item
  22. PORCN 1 item
  23. FGFR 1 item
  24. GABAB Receptors 1 item
  25. Smoothened 1 item
  26. Src 1 item
  27. NMDA Receptors 1 item
  28. STAT 6item
  29. EGFR 2item
  30. Hedgehog 1 item
  31. BMP and Other Activin Receptors 2item
  32. JAK 3item
  33. Syk 1 item
  34. DNA-PK 8item
  35. HSP90 1 item
  36. TNKS 1 item
  37. Toll-like receptors (TLRs) 1 item
  38. ERK 2item
  39. PKC 6item
  40. Melanocortin (MC) Receptors 1 item
  41. ALK 1 item
  42. PKG 1 item
  43. PKA 4item
  44. Fatty-acid-binding proteins (FABPs) 1 item
  45. RSK 1 item
  46. ATM/ATR 2item
  47. Histamine H1 Receptors 1 item
  48. P110 1 item
  49. Hck 1 item
  50. NO Donors / Precursors 1 item
  51. IL Receptors 1 item
  52. AChE 1 item
  53. BACE 1 item
  54. p70 rsk 1 item
  55. sodium channels 1 item
  56. Smoothened receptor 1 item
  57. Nrf2/ARE signal 1 item
  58. PPAR 1 item
  59. Antibiotic 1 item
  60. Prk 1 item
  61. ICAM 1 item
  62. Rho 1 item
  63. Thrombin Receptor 1 item
  64. prolactin secretion 1 item
  65. gonadotropin release 1 item
  66. TRPC channel 1 item
  67. PKD 1 item
  68. FKBP 1 item
  69. ATM 1 item
Reported Experiments
  1. Animal Experiments 137item
  2. Cell Experiments 107item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 2item
  3. Bladder Cancer 1 item
  4. Breast Cancer 24item
  5. Cancer 89item
  6. Cervical Cancer 2item
  7. Cholangiocarcinoma 1 item
  8. Chronic Lymphocytic Leukemia 1 item
  9. Colon Cancer 10item
  10. Colon Carcinoma 1 item
  11. Colorectal Cancer 11item
  12. Glioblastoma 11item
  13. Glioma 4item
  14. Heart Failure 1 item
  15. Hepatocellular Carcinoma 1 item
  16. Leukemia 6item
  17. Liver Cancer 1 item
  18. Lung Cancer 7item
  19. Lymphoma 2item
  20. Melanoma 7item
  21. Multiple Myeloma 1 item
  22. Myeloma 1 item
  23. Neuroblastoma 2item
  24. Non-small Cell Lung Cancer 6item
  25. Ovarian Cancer 7item
  26. Pancreatic Cancer 10item
  27. Pancreatic Carcinoma 2item
  28. Prostate Cancer 11item
  29. Pulmonary Arterial Hypertension 1 item
  30. Pulmonary Fibrosis 1 item
  31. Renal Cancer 2item
  32. Rheumatoid Arthritis 2item
  33. Thyroid Cancer 2item
  34. Type 2 Diabetes 2item