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  • Search results for: 'research area pi3k akt signaling pdk 1'

Search results for: 'research area pi3k akt signaling pdk 1'

Items 151-160 of 265

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  1. TW-37
    A4234 TW-37
     1 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor, inhibits Bcl-2,Bcl-XL and Mcl-1
      insoluble in H2O; ≥19.75 mg/mL
  2. LKB1 (AAK1 dual inhibitor)
    A3556 LKB1 (AAK1 dual inhibitor)
    Target: Pim
    Summary: Pim-1 kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥34.8 mg/mL
  3. Niclosamide
    B2283 Niclosamide
    Target: STAT
    Summary: Inhibitor of the STAT3 signaling pathway
  4. HS-173
    B4492 HS-173
    Target: PI3K
    Summary: novel PI3K inhibitor
      ≥21.1 mg/mL
  5. PX 12
    A4509 PX 12
    Target: Trx
    Summary: Trx-1 inhibitor
      insoluble in H2O; ≥8.75 mg/mL
  6. Veliparib dihydrochloride
    A3958 Veliparib dihydrochloride
    Target: PARP
    Summary: PARP-1/PARP-2 inhibitor
      ≥31.7 mg/mL
  7. SP2509
    B4894 SP2509
    Target: Histone Demethylases
    Summary: Demethylase 1 (LSD1) antagonist, novel Lysine-specific
      insoluble in H2O; insoluble in EtOH; ≥19.45 mg/mL
  8. Refametinib
    B1267 Refametinib
    Target: MEK
    Summary: MEK 1/ MEK 2 inhibitor
      insoluble in H2O; ≥151.8 mg/mL
  9. Gefitinib hydrochloride
    A3433 Gefitinib hydrochloride
    Target: EGFR
    Summary: Potent EGFR inhibitor
      insoluble in EtOH; ≥4.28 mg/mL
  10. Sabutoclax
    A4199 Sabutoclax
     2 Citation
    Target: Bcl-2|Mcl-1|Bfl-1
    Summary: pan-Bcl-2 inhibitor
      insoluble in H2O; ≥205.6 mg/mL

Items 151-160 of 265

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  1. Category Signaling Pathways Remove This Item
  2. Related Disease Cancer Remove This Item
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Category
  1. Proteases 10item
  2. Apoptosis 21item
  3. Chromatin/Epigenetics 32item
  4. Metabolism 8item
  5. MAPK Signaling 21item
  6. Tyrosine Kinase 36item
  7. DNA Damage/DNA Repair 24item
  8. PI3K/Akt/mTOR Signaling 40item
  9. Microbiology & Virology 3item
  10. Cell Cycle/Checkpoint 32item
  11. Ubiquitination/ Proteasome 9item
  12. JAK/STAT Signaling 13item
  13. TGF-β / Smad Signaling 12item
  14. Angiogenesis 2item
  15. GPCR/G protein 7item
  16. Stem Cell 19item
  17. Membrane Transporter/Ion Channel 2item
  18. Endocrinology and Hormones 5item
  19. Neuroscience 7item
  20. Others 13item
  21. Immunology/Inflammation 4item
Specificity
  1. Selective 211item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 13item
  2. Irreversible 5item
Target
  1. Caspases 2item
  2. Cyclin-Dependent Kinases 12item
  3. Proteasome 1 item
  4. Histone Deacetylases (HDACs) 8item
  5. Akt 10item
  6. Bcl-2 7item
  7. PI3K 23item
  8. CXCR 1 item
  9. Raf 9item
  10. Aurora Kinases 5item
  11. Bcl-xl 2item
  12. CSF-1R 1 item
  13. MDM2 1 item
  14. EZH2 3item
  15. mTOR 13item
  16. Bromodomains 1 item
  17. AP-1 1 item
  18. MMP 3item
  19. Androgen Receptors 3item
  20. FLT3 6item
  21. GSK-3 4item
  22. LPA Receptors 1 item
  23. P-glycoprotein (P-gp) 1 item
  24. PLK 6item
  25. Chk 2item
  26. VEGFR 22item
  27. PDGFR 11item
  28. c-Kit 4item
  29. RET 3item
  30. Bromodomain-containing proteins(BRDs) 1 item
  31. Phosphodiesterases (PDEs) 1 item
  32. Mcl-1 5item
  33. p38 2item
  34. JNK 1 item
  35. SGK 2item
  36. Bcr-Abl 3item
  37. MEK 8item
  38. PORCN 1 item
  39. DOT1L 1 item
  40. FGFR 3item
  41. Insulin-like growth factor receptors(IGFRs) 1 item
  42. Pim 1 item
  43. Liver X receptors (LXRs) 1 item
  44. Sir2-like Family Deacetylases (Sirtuins) 2item
  45. Deubiquitinating enzymes (DUBs) 2item
  46. PP1 1 item
  47. PP2A 1 item
  48. Smoothened 2item
  49. MET 1 item
  50. Src 5item
  51. Trk Receptors 2item
  52. Aminopeptidases 1 item
  53. STAT 6item
  54. Microtubules/Tubulins 4item
  55. Estrogen and Related Receptors 1 item
  56. EGFR 4item
  57. Hedgehog 1 item
  58. PAK 1 item
  59. Hypoxia Inducible Factors (HIFs) 1 item
  60. BMP and Other Activin Receptors 1 item
  61. JAK 5item
  62. p300 1 item
  63. Syk 1 item
  64. EZH1 1 item
  65. DNA-PK 4item
  66. HSP90 2item
  67. Gutathione S-transferase 1 item
  68. CCR 1 item
  69. eIF4E/eIF3G interaction 1 item
  70. TNKS 1 item
  71. Topoisomerases 3item
  72. Cytochrome P450 (CYP450) 2item
  73. ERK 3item
  74. Vacuolar-type ATPase 1 item
  75. c-MET 3item
  76. BMI-1 1 item
  77. PKC 6item
  78. Calpains 1 item
  79. RAD51 1 item
  80. 5-HT2 Receptors 2item
  81. Calcium chelator 1 item
  82. PARP 3item
  83. ALK 1 item
  84. Sphingosine kinases (SphKs) 2item
  85. Monocarboxylate transporters (MCTs) 1 item
  86. PKG 1 item
  87. PKA 4item
  88. GPR30 1 item
  89. D2 Receptors 1 item
  90. MK2 1 item
  91. Tie-2 1 item
  92. RSK 1 item
  93. Autophagy 3item
  94. ATM/ATR 2item
  95. COX 2item
  96. YAP 1 item
  97. CK1 1 item
  98. CK2 1 item
  99. G-quadruplexes 1 item
  100. Nampt 1 item
  101. P2X Receptors 1 item
  102. Glutaminases 1 item
  103. Carbonic Anhydrases 1 item
  104. Ron 1 item
  105. BLM 1 item
  106. Synthases/Synthetases 1 item
  107. MAGL 1 item
  108. Inositol-requiring enzyme 1 (IRE1) 1 item
  109. RNA Polymerases 1 item
  110. Norepinephrine transporter 1 item
  111. 5-HT Transporters 1 item
  112. Guanylyl Cyclases 1 item
  113. Histone Demethylases 1 item
  114. MNK 1 item
  115. HIV-1 reverse transcriptase 1 item
  116. Insulin Receptors 1 item
  117. IRG-1R 1 item
  118. eEF-2 1 item
  119. ZAP-70 1 item
  120. Protein Arginine Methyltransferases 1 item
  121. BACE 1 item
  122. PP4 1 item
  123. p70 rsk 2item
  124. VEGFR3/FLT4 1 item
  125. NTRK1/TRKA 1 item
  126. CSF-1R/c-Fms 1 item
  127. NMPRTase 1 item
  128. Bfl-1 1 item
  129. KDR 1 item
  130. p53 2item
  131. Smoothened receptor 1 item
  132. Antibiotic 1 item
  133. Hec1 1 item
  134. PDK-1 1 item
  135. Prk 1 item
  136. Trx 1 item
  137. HSP70 1 item
  138. Adenosine Deaminases 1 item
  139. Flk1 1 item
  140. MCL1 1 item
  141. Bcl-w 1 item
  142. PPK 1 item
  143. c-Syk 1 item
  144. CDK1/CyclinB 1 item
  145. Substance P/NK1 Receptor 1 item
Reported Experiments
  1. Animal Experiments 249item
  2. Cell Experiments 169item