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Search results for: 'research area pi3k akt signaling pdk 1'

Search results for: 'research area pi3k akt signaling pdk 1'

A4413 PD 150606

Target: Calpains

Summary: Non-peptide calpain inhibitor

Soluble in DMSO
B1577 C646

1 Citation

Target: p300

Summary: HAT p300-CBP inhibitor,cell-permeable

insoluble in H2O; ≥11.14 mg/mL
A3887 Trametinib DMSO solvate

1 Citation

Target: MEK

Summary: Allosteric MEK1/MEK2 kinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥11.2 mg/mL
A4381 FK866 (APO866)

1 Citation

Target: Nampt

Summary: NAMPT inhibitor, non-competitive, highly specific

insoluble in H2O; ≥19.6 mg/mL
A8374 AZD8330

Target: MEK

Summary: MEK 1/2 inhibitor

≥23.05 mg/mL
B2186 GSK2636771

Target: PI3K

Summary: PIK3 inhibitor

insoluble in H2O; insoluble in EtOH; ≥10.83 mg/mL
B4900 Indoximod (NLG-8189)

Summary: Indoleamine 2,3-dioxygenase (IDO) pathway inhibitor

insoluble in DMSO; insoluble in EtOH; ≥1.12 mg/mL
A8370 Axitinib (AG 013736)

1 Citation

Target: VEGFR|PDGFR|c-Kit

Summary: VEGFR1/ c-Kit inhibitor

insoluble in H2O; ≥19.3 mg/mL
A3170 AM966

2 Citation

Target: LPA Receptors

Summary: LPA1 antagonist, oral active, high affinity, selective,

≥24.55 mg/mL