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  • Search results for: 'research area pi3k akt signaling pdk 1'

Search results for: 'research area pi3k akt signaling pdk 1'

Items 221-230 of 265

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  1. Apogossypolone (ApoG2)
    A4200 Apogossypolone (ApoG2)
     2 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor,nonpeptidic small molecule
      ≥24.55 mg/mL
  2. Cediranib (AZD217)
    A1882 Cediranib (AZD217)
    Target: VEGFR
    Summary: VEGFR inhibitor receptor,highly potent
      ≥22.52 mg/mL
  3. NSC 405020
    A4051 NSC 405020
     1 Citation
    Target: MMP
    Summary: MT1-MMP inhibitor
      insoluble in H2O; ≥11.4 mg/mL
  4. GSK343
    A3449 GSK343
     1 Citation
    Target: EZH2
    Summary: EZH2 inhibitor,potent,selective and cell permeable
  5. BMS-833923
    A3258 BMS-833923
    Target: Smoothened
    Summary: Smoothened inhibitor
      ≥47.4 mg/mL
  6. HPOB
    B4890 HPOB
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC6 inhibitor, potent and selective
      ≥31.4 mg/mL
  7. Indoximod (NLG-8189)
    B4900 Indoximod (NLG-8189)
    Summary: Indoleamine 2,3-dioxygenase (IDO) pathway inhibitor
      insoluble in DMSO; insoluble in EtOH; ≥1.12 mg/mL
  8. Actinomycin D
    A4448 Actinomycin D
     15 Citation
    Summary: RNA polymerase inhibitor
      ≥62.75 mg/mL
  9. Pifithrin-μ
    A4482 Pifithrin-μ
     1 Citation
    Target: Autophagy|p53|HSP70
    Summary: Inhibitor of p53 binding and anti-apoptotic
      insoluble in H2O; ≥18.1 mg/mL
  10. Chloroquine diphosphate
    A8628 Chloroquine diphosphate
     1 Citation
    Target: Autophagy
    Summary: Antimalarial drug,TLR7 TLR9 inhibitor
      insoluble in DMSO; insoluble in EtOH; ≥106.06 mg/mL

Items 221-230 of 265

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  1. Category Signaling Pathways Remove This Item
  2. Related Disease Cancer Remove This Item
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Category
  1. Proteases 10item
  2. Apoptosis 21item
  3. Chromatin/Epigenetics 32item
  4. Metabolism 8item
  5. MAPK Signaling 21item
  6. Tyrosine Kinase 36item
  7. DNA Damage/DNA Repair 24item
  8. PI3K/Akt/mTOR Signaling 40item
  9. Microbiology & Virology 3item
  10. Cell Cycle/Checkpoint 32item
  11. Ubiquitination/ Proteasome 9item
  12. JAK/STAT Signaling 13item
  13. TGF-β / Smad Signaling 12item
  14. Angiogenesis 2item
  15. GPCR/G protein 7item
  16. Stem Cell 19item
  17. Membrane Transporter/Ion Channel 2item
  18. Endocrinology and Hormones 5item
  19. Neuroscience 7item
  20. Others 13item
  21. Immunology/Inflammation 4item
Specificity
  1. Selective 211item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 13item
  2. Irreversible 5item
Target
  1. Caspases 2item
  2. Cyclin-Dependent Kinases 12item
  3. Proteasome 1 item
  4. Histone Deacetylases (HDACs) 8item
  5. Akt 10item
  6. Bcl-2 7item
  7. PI3K 23item
  8. CXCR 1 item
  9. Raf 9item
  10. Aurora Kinases 5item
  11. Bcl-xl 2item
  12. CSF-1R 1 item
  13. MDM2 1 item
  14. EZH2 3item
  15. mTOR 13item
  16. Bromodomains 1 item
  17. AP-1 1 item
  18. MMP 3item
  19. Androgen Receptors 3item
  20. FLT3 6item
  21. GSK-3 4item
  22. LPA Receptors 1 item
  23. P-glycoprotein (P-gp) 1 item
  24. PLK 6item
  25. Chk 2item
  26. VEGFR 22item
  27. PDGFR 11item
  28. c-Kit 4item
  29. RET 3item
  30. Bromodomain-containing proteins(BRDs) 1 item
  31. Phosphodiesterases (PDEs) 1 item
  32. Mcl-1 5item
  33. p38 2item
  34. JNK 1 item
  35. SGK 2item
  36. Bcr-Abl 3item
  37. MEK 8item
  38. PORCN 1 item
  39. DOT1L 1 item
  40. FGFR 3item
  41. Insulin-like growth factor receptors(IGFRs) 1 item
  42. Pim 1 item
  43. Liver X receptors (LXRs) 1 item
  44. Sir2-like Family Deacetylases (Sirtuins) 2item
  45. Deubiquitinating enzymes (DUBs) 2item
  46. PP1 1 item
  47. PP2A 1 item
  48. Smoothened 2item
  49. MET 1 item
  50. Src 5item
  51. Trk Receptors 2item
  52. Aminopeptidases 1 item
  53. STAT 6item
  54. Microtubules/Tubulins 4item
  55. Estrogen and Related Receptors 1 item
  56. EGFR 4item
  57. Hedgehog 1 item
  58. PAK 1 item
  59. Hypoxia Inducible Factors (HIFs) 1 item
  60. BMP and Other Activin Receptors 1 item
  61. JAK 5item
  62. p300 1 item
  63. Syk 1 item
  64. EZH1 1 item
  65. DNA-PK 4item
  66. HSP90 2item
  67. Gutathione S-transferase 1 item
  68. CCR 1 item
  69. eIF4E/eIF3G interaction 1 item
  70. TNKS 1 item
  71. Topoisomerases 3item
  72. Cytochrome P450 (CYP450) 2item
  73. ERK 3item
  74. Vacuolar-type ATPase 1 item
  75. c-MET 3item
  76. BMI-1 1 item
  77. PKC 6item
  78. Calpains 1 item
  79. RAD51 1 item
  80. 5-HT2 Receptors 2item
  81. Calcium chelator 1 item
  82. PARP 3item
  83. ALK 1 item
  84. Sphingosine kinases (SphKs) 2item
  85. Monocarboxylate transporters (MCTs) 1 item
  86. PKG 1 item
  87. PKA 4item
  88. GPR30 1 item
  89. D2 Receptors 1 item
  90. MK2 1 item
  91. Tie-2 1 item
  92. RSK 1 item
  93. Autophagy 3item
  94. ATM/ATR 2item
  95. COX 2item
  96. YAP 1 item
  97. CK1 1 item
  98. CK2 1 item
  99. G-quadruplexes 1 item
  100. Nampt 1 item
  101. P2X Receptors 1 item
  102. Glutaminases 1 item
  103. Carbonic Anhydrases 1 item
  104. Ron 1 item
  105. BLM 1 item
  106. Synthases/Synthetases 1 item
  107. MAGL 1 item
  108. Inositol-requiring enzyme 1 (IRE1) 1 item
  109. RNA Polymerases 1 item
  110. Norepinephrine transporter 1 item
  111. 5-HT Transporters 1 item
  112. Guanylyl Cyclases 1 item
  113. Histone Demethylases 1 item
  114. MNK 1 item
  115. HIV-1 reverse transcriptase 1 item
  116. Insulin Receptors 1 item
  117. IRG-1R 1 item
  118. eEF-2 1 item
  119. ZAP-70 1 item
  120. Protein Arginine Methyltransferases 1 item
  121. BACE 1 item
  122. PP4 1 item
  123. p70 rsk 2item
  124. VEGFR3/FLT4 1 item
  125. NTRK1/TRKA 1 item
  126. CSF-1R/c-Fms 1 item
  127. NMPRTase 1 item
  128. Bfl-1 1 item
  129. KDR 1 item
  130. p53 2item
  131. Smoothened receptor 1 item
  132. Antibiotic 1 item
  133. Hec1 1 item
  134. PDK-1 1 item
  135. Prk 1 item
  136. Trx 1 item
  137. HSP70 1 item
  138. Adenosine Deaminases 1 item
  139. Flk1 1 item
  140. MCL1 1 item
  141. Bcl-w 1 item
  142. PPK 1 item
  143. c-Syk 1 item
  144. CDK1/CyclinB 1 item
  145. Substance P/NK1 Receptor 1 item
Reported Experiments
  1. Animal Experiments 249item
  2. Cell Experiments 169item