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  • Search results for: 'research area pi3k akt signaling pdk 1'

Search results for: 'research area pi3k akt signaling pdk 1'

Items 71-80 of 393

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  1. SB-505124 hydrochloride
    A3799 SB-505124 hydrochloride
    Target: ALK
    Summary: ALK5/ALK4/ALK7 inhibitor in TGF-β/activin signalling,selective
  2. GDC-0879
    A5071 GDC-0879
     1 Citation
    Target: Raf
    Summary: B-Raf inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥16.7 mg/mL
  3. SB202190 (FHPI)
    A1632 SB202190 (FHPI)
     5 Citation
    Target: p38
    Summary: P38 MAPK inhibitor
  4. Trametinib (GSK1120212)
    A3018 Trametinib (GSK1120212)
     7 Citation
    Target: MEK
    Summary: MEK1 and MEK2 inhibitor, potent and selective
      insoluble in H2O; insoluble in EtOH; ≥15.38 mg/mL
  5. Enzastaurin (LY317615)
    A1670 Enzastaurin (LY317615)
     2 Citation
    Target: PKC
    Summary: PKC beta inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥8.59 mg/mL
  6. GDC-0941
    A8210 GDC-0941
     10 Citation
    Target: PI3K
    Summary: PI3K inhibitor,potent and selective
      ≥25.7 mg/mL
  7. OSU-03012 (AR-12)
    A2846 OSU-03012 (AR-12)
     1 Citation
    Target: PDK-1
    Summary: Potent PDK1 inhibitor
      ≥23 mg/mL
  8. AICAR
    A8184 AICAR
     3 Citation
    Target: AMPK
    Summary: AMPK activator
      insoluble in EtOH; ≥12.9 mg/mL
  9. THZ2
    A8717 THZ2
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK7 inhibitor
      ≥28.3 mg/mL
  10. Salinomycin
    A3785 Salinomycin
    Target: Antibiotic
    Summary: Polyether ionophore antibiotic;anti-cancer

Items 71-80 of 393

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Category
  1. Proteases 25item
  2. Apoptosis 29item
  3. Chromatin/Epigenetics 36item
  4. Metabolism 23item
  5. MAPK Signaling 22item
  6. Tyrosine Kinase 37item
  7. DNA Damage/DNA Repair 24item
  8. PI3K/Akt/mTOR Signaling 49item
  9. Microbiology & Virology 19item
  10. Cell Cycle/Checkpoint 29item
  11. Ubiquitination/ Proteasome 5item
  12. JAK/STAT Signaling 14item
  13. TGF-β / Smad Signaling 12item
  14. Angiogenesis 4item
  15. GPCR/G protein 16item
  16. Stem Cell 18item
  17. Membrane Transporter/Ion Channel 15item
  18. Cancer Biology 3item
  19. Endocrinology and Hormones 10item
  20. Neuroscience 27item
  21. Obesity, Appetite Control & Diabetes 1 item
  22. Other Signal Transduction 7item
  23. Others 27item
  24. Immunology/Inflammation 12item
  25. Cardiovascular 5item
  26. Vitamin D Related 2item
  27. NF-κB 1 item
Specificity
  1. Selective 226item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 11item
  2. Irreversible 7item
Target
  1. Caspases 3item
  2. Cyclin-Dependent Kinases 12item
  3. Proteasome 1 item
  4. Cathepsins 2item
  5. Histone Deacetylases (HDACs) 6item
  6. Inhibitor of apoptosis proteins (IAP) 1 item
  7. Akt 10item
  8. Bcl-2 7item
  9. PI3K 23item
  10. Raf 7item
  11. Aurora Kinases 5item
  12. Bcl-xl 2item
  13. CSF-1R 1 item
  14. Gap Junctions 1 item
  15. MDM2 2item
  16. EZH2 1 item
  17. mTOR 14item
  18. Bromodomains 2item
  19. AP-1 3item
  20. MMP 5item
  21. Androgen Receptors 2item
  22. Acyl coenzyme A: cholesterol acyltransferases 1 item
  23. FLT3 10item
  24. GSK-3 6item
  25. Factor Xa 1 item
  26. LPA Receptors 2item
  27. PLK 5item
  28. Chk 2item
  29. VEGFR 18item
  30. PDGFR 12item
  31. c-Kit 5item
  32. RET 2item
  33. IRAK 1 item
  34. Bromodomain-containing proteins(BRDs) 1 item
  35. Phosphodiesterases (PDEs) 2item
  36. Mcl-1 5item
  37. p38 6item
  38. PKB 1 item
  39. JNK 1 item
  40. Bcr-Abl 4item
  41. MEK 7item
  42. PORCN 1 item
  43. DOT1L 1 item
  44. FGFR 3item
  45. Pim 1 item
  46. GABAB Receptors 1 item
  47. Liver X receptors (LXRs) 1 item
  48. Sir2-like Family Deacetylases (Sirtuins) 1 item
  49. Voltage-gated Sodium (NaV) Channels 1 item
  50. Deubiquitinating enzymes (DUBs) 1 item
  51. PP1 1 item
  52. PP2A 1 item
  53. MET 1 item
  54. Src 7item
  55. Trk Receptors 3item
  56. Aminopeptidases 1 item
  57. NMDA Receptors 2item
  58. STAT 5item
  59. Estrogen and Related Receptors 2item
  60. EGFR 3item
  61. ROCK 1 item
  62. Hypoxia Inducible Factors (HIFs) 1 item
  63. JAK 8item
  64. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  65. Syk 1 item
  66. Progesterone Receptors 1 item
  67. EZH1 1 item
  68. DNA-PK 4item
  69. HSP90 2item
  70. AMPK 1 item
  71. CCR 1 item
  72. Topoisomerases 5item
  73. Cytochrome P450 (CYP450) 2item
  74. Toll-like receptors (TLRs) 2item
  75. Actin 1 item
  76. DNA Methyltransferases 2item
  77. ERK 4item
  78. c-MET 3item
  79. PKC 6item
  80. Calpains 1 item
  81. Protease-Activated Receptors 1 item
  82. RAD51 1 item
  83. 5-HT2 Receptors 2item
  84. LRRK2 1 item
  85. DGAT 1 item
  86. Insulin and Insulin-like Receptors 2item
  87. PARP 4item
  88. CB1 Receptors 1 item
  89. ALK 2item
  90. Sphingosine kinases (SphKs) 1 item
  91. Monocarboxylate transporters (MCTs) 1 item
  92. PKG 1 item
  93. PKA 4item
  94. GPR30 1 item
  95. Tie-2 2item
  96. RSK 1 item
  97. phosphatases 1 item
  98. Autophagy 2item
  99. ATM/ATR 2item
  100. COX 6item
  101. YAP 1 item
  102. CK1 1 item
  103. CK2 1 item
  104. HIV Integrases 1 item
  105. Nampt 1 item
  106. P2X Receptors 1 item
  107. Glutaminases 1 item
  108. Carbonic Anhydrases 2item
  109. Ron 1 item
  110. BLM 1 item
  111. HSV 1 item
  112. NADPH Oxidases 1 item
  113. Calcium-activated chloride channels (CaCC) 1 item
  114. GPR35 1 item
  115. Aldehyde Dehydrogenases 1 item
  116. MAGL 1 item
  117. Leukotriene and Related Receptors 1 item
  118. Histamine H1 Receptors 2item
  119. RAR/RXR 1 item
  120. Inositol-requiring enzyme 1 (IRE1) 1 item
  121. Na /K /Cl- Symporters (NKCCs) 1 item
  122. TRP Channel 2item
  123. RNA Polymerases 1 item
  124. Norepinephrine transporter 1 item
  125. 5-HT Transporters 1 item
  126. Guanylyl Cyclases 1 item
  127. Histone Demethylases 1 item
  128. MNK 2item
  129. NO Donors / Precursors 1 item
  130. CB2 Receptors 1 item
  131. HIV-1 reverse transcriptase 1 item
  132. IL Receptors 1 item
  133. 15-lipoxygenases 1 item
  134. AChE 1 item
  135. Insulin Receptors 1 item
  136. IRG-1R 1 item
  137. eEF-2 1 item
  138. CRTH2 1 item
  139. Nuclear Receptors 1 item
  140. ZAP-70 1 item
  141. Angiotensin AT1 Receptors 2item
  142. Protein Arginine Methyltransferases 1 item
  143. Na /Ca2 Exchangers (NCXs) 1 item
  144. Ubiquitin-activating Enzyme E1 1 item
  145. BACE 1 item
  146. Glucagon Receptors 1 item
  147. PP4 1 item
  148. c-RET 1 item
  149. Nonstructural protein 5B (NS5B) 1 item
  150. guanylyl cyclase 1 item
  151. ETA Receptors 2item
  152. ETB Receptors 1 item
  153. p70 rsk 3item
  154. voltage-gated chloride channels 1 item
  155. 5-HT1 Receptor 1 item
  156. VEGFR3/FLT4 1 item
  157. NTRK1/TRKA 1 item
  158. CSF-1R/c-Fms 1 item
  159. Menin-MLL 2item
  160. Tryptophan hydroxylases (TPH) 1 item
  161. NMPRTase 1 item
  162. Bfl-1 1 item
  163. sodium channels 1 item
  164. KDR 1 item
  165. Fyn kinase 1 item
  166. dCTP Pyrophosphatases 1 item
  167. Protein polybromo-1 1 item
  168. SMARCA4 1 item
  169. SMARCA2 1 item
  170. p53 4item
  171. metalloprotease 1 item
  172. Antifungal 1 item
  173. 5-HT receptors 1 item
  174. sodium channel 1 item
  175. c-Fms tyrosine kinase 1 item
  176. PAR 1 item
  177. Smoothened receptor 1 item
  178. Nrf2/ARE signal 1 item
  179. PPAR 2item
  180. USP1/USF1 complex 1 item
  181. IKK 1 item
  182. TRPV 1 item
  183. Ftase 1 item
  184. Elastases 1 item
  185. ATP synthase 1 item
  186. Vitamin D receptors (VDRs) 1 item
  187. Antibiotic 3item
  188. Mer tyrosine kinase 1 item
  189. Hec1 1 item
  190. Stem Cell Differentiation 1 item
  191. PP2A/Nkd interaction 1 item
  192. HMGCR 1 item
  193. HIV 1 item
  194. TRPA 1 item
  195. PDK-1 1 item
  196. telomerase 1 item
  197. Prk 1 item
  198. Trx 1 item
  199. Neurokinin receptor 1 item
  200. HSP70 1 item
  201. ICAM 1 item
  202. ITK 1 item
  203. NOD1 1 item
  204. Rho 1 item
  205. Aryl hydrocarbon receptors (AHRs) 1 item
  206. Ubiquitin E3 Ligases 1 item
  207. DCLK2 1 item
  208. integrase 1 item
  209. L3MBTL 1 item
  210. NOS 1 item
  211. GPR3 1 item
  212. Lck 1 item
  213. Adenosine Deaminases 1 item
  214. mitochondrial pyruvate carrier (MPC) 1 item
  215. DNA gyrase 1 item
  216. Thrombin Receptor 1 item
  217. prolactin secretion 1 item
  218. gonadotropin release 1 item
  219. DprE 1 item
  220. Vitamin D 1 item
  221. Flk1 1 item
  222. SAPK 1 item
  223. p21 1 item
  224. Prostaglandin synthesis 1 item
  225. glutamate release 1 item
  226. Aromatases 1 item
  227. 5-HT 1 item
  228. TRPC channel 1 item
  229. PKD 1 item
  230. Octamer-binding transcription factor 4 (Oct4) 1 item
  231. FKBP 1 item
  232. MCL1 1 item
  233. Bcl-w 1 item
  234. ACE 1 item
  235. MST 1 item
  236. PPK 1 item
  237. c-Syk 1 item
  238. CDK1/CyclinB 1 item
  239. Tph 1 item
  240. reverse transcriptase 1 item
  241. Cholesterol absorption 1 item
  242. Substance P/NK1 Receptor 1 item
  243. gp120/CD4 1 item
  244. ATM 1 item
  245. PTEN 1 item
  246. NS3/4a Proteases 1 item
  247. p90 S6K 1 item
Related Disease
  1. Acute Lung Injury 1 item
  2. Acute Myelogenous Leukemia 1 item
  3. Acute Myeloid Leukemia 8item
  4. Adrenocortical Carcinoma 1 item
  5. Biliary Cancer 1 item
  6. Bladder Cancer 2item
  7. Bladder Diseases 1 item
  8. Brain Injuries Studies 1 item
  9. Breast Cancer 38item
  10. Cancer 169item
  11. Cervical Cancer 3item
  12. Chronic Lymphocytic Leukemia 2item
  13. Clear Cell Renal Cell Carcinoma 1 item
  14. Colon Cancer 10item
  15. Colon Carcinoma 1 item
  16. Colorectal Cancer 14item
  17. Diabetes 1 item
  18. Epilepsy 2item
  19. Glioblastoma 13item
  20. Glioma 6item
  21. HCV 1 item
  22. Heart Failure 3item
  23. Hepatitis C 1 item
  24. Hepatocellular Carcinoma 1 item
  25. HIV 5item
  26. HIV Infections 4item
  27. Hypercholesterolemia 1 item
  28. Inflammatory Diseases 6item
  29. Leukemia 13item
  30. Liver Cancer 1 item
  31. Lung Cancer 9item
  32. Lung Carcinoma 1 item
  33. Lymphoma 12item
  34. Melanoma 10item
  35. Mixed Lineage Leukemia 1 item
  36. Multiple Myeloma 4item
  37. Myelofibrosis 1 item
  38. Myeloma 1 item
  39. Neuroblastoma 3item
  40. Non-small Cell Lung Cancer 9item
  41. Osteoporosis 1 item
  42. Ovarian Cancer 12item
  43. Pancreatic Cancer 15item
  44. Pancreatic Carcinoma 1 item
  45. Pentacyclic Triterpenoid 1 item
  46. Prostate Cancer 15item
  47. Psoriasis 1 item
  48. Pulmonary Fibrosis 1 item
  49. Renal Cancer 2item
  50. Renal Cell Carcinoma 1 item
  51. Rheumatoid Arthritis 5item
  52. Sleep Disorders 1 item
  53. Squamous Cell Carcinoma 1 item
  54. Thyroid Cancer 3item
  55. Tuberculosis 3item
  56. Type 2 Diabetes 5item