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  • Search results for: 'research area pi3k akt signaling pdk 1'

Search results for: 'research area pi3k akt signaling pdk 1'

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  1. AKT inhibitor VIII
    A3149 AKT inhibitor VIII
     2 Citation
    Target: Akt
    Summary: Allosteric Akt kinase inhibitor
      insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL
  2. Torin 1
    A8312 Torin 1
     7 Citation
    Target: mTOR
    Summary: MTOR inhibitor,potent and selective
  3. AZD5363
    A1387 AZD5363
     3 Citation
    Target: Akt
    Summary: AKT inhibitor,pyrrolopyrimidine derived
      ≥21.45 mg/mL
  4. Perifosine
    A8309 Perifosine
     1 Citation
    Target: Akt
    Summary: Akt inhibitor
  5. GDC-0068 (RG7440)
    A3006 GDC-0068 (RG7440)
    Target: Akt
    Summary: Pan-AKT inhibitor,highly selective
      ≥22.9 mg/mL
  6. CCT128930 HCl
    A8617 CCT128930 HCl
    Target: Akt
    Summary: AKT inhibitor
      insoluble in H2O; ≥17.1 mg/mL
  7. BKM120
    A3015 BKM120
     1 Citation
    Target: PI3K
    Summary: Inhibitor of pan-Class I PI3K
      ≥20.52 mg/mL
  8. XL147
    A5112 XL147
    Target: PI3K
    Summary: PI3K inhibitor,selective and reversible
      ≥22.45 mg/mL
  9. AT7867
    A5653 AT7867
    Target: Akt|PKA|p70 rsk
    Summary: Akt1/2/3 and p70S6K/PKA inhibitor
      ≥16.9 mg/mL
  10. PP242
    A8318 PP242
    Target: mTOR
    Summary: MTOR inhibitor, selective and ATP-competitive

Items 1-10 of 486

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Category
  1. Proteases 34item
  2. Apoptosis 35item
  3. Chromatin/Epigenetics 45item
  4. Metabolism 28item
  5. MAPK Signaling 30item
  6. Tyrosine Kinase 54item
  7. DNA Damage/DNA Repair 35item
  8. PI3K/Akt/mTOR Signaling 62item
  9. Microbiology & Virology 23item
  10. Cell Cycle/Checkpoint 33item
  11. Ubiquitination/ Proteasome 7item
  12. JAK/STAT Signaling 18item
  13. TGF-β / Smad Signaling 20item
  14. Angiogenesis 4item
  15. GPCR/G protein 26item
  16. Stem Cell 24item
  17. Membrane Transporter/Ion Channel 15item
  18. Cancer Biology 1 item
  19. Endocrinology and Hormones 12item
  20. Neuroscience 29item
  21. Obesity, Appetite Control & Diabetes 2item
  22. Other Signal Transduction 6item
  23. Others 29item
  24. Immunology/Inflammation 12item
  25. Cardiovascular 5item
  26. Vitamin D Related 2item
  27. NF-κB 1 item
Specificity
  1. Selective 333item
  2. Non-Selective 2item
Reversibility
  1. Reversible 18item
  2. Irreversible 9item
Target
  1. Caspases 5item
  2. Cyclin-Dependent Kinases 11item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 1 item
  5. Cathepsins 3item
  6. Histone Deacetylases (HDACs) 11item
  7. Inhibitor of apoptosis proteins (IAP) 1 item
  8. Akt 12item
  9. Bcl-2 8item
  10. PI3K 32item
  11. CXCR 1 item
  12. Raf 9item
  13. Aurora Kinases 5item
  14. Bcl-xl 2item
  15. CSF-1R 1 item
  16. Gap Junctions 1 item
  17. MDM2 2item
  18. EZH2 1 item
  19. mTOR 18item
  20. Bromodomains 2item
  21. AP-1 3item
  22. MMP 6item
  23. Androgen Receptors 4item
  24. Acyl coenzyme A: cholesterol acyltransferases 1 item
  25. FLT3 11item
  26. GSK-3 8item
  27. Factor Xa 1 item
  28. LPA Receptors 3item
  29. P-glycoprotein (P-gp) 1 item
  30. PLK 6item
  31. Chk 3item
  32. VEGFR 24item
  33. PDGFR 14item
  34. c-Kit 6item
  35. RET 3item
  36. IRAK 1 item
  37. Bromodomain-containing proteins(BRDs) 1 item
  38. Phosphodiesterases (PDEs) 2item
  39. Mcl-1 6item
  40. p38 6item
  41. PKB 1 item
  42. JNK 3item
  43. SGK 1 item
  44. Bcr-Abl 5item
  45. MEK 8item
  46. PORCN 1 item
  47. DOT1L 1 item
  48. FGFR 4item
  49. Insulin-like growth factor receptors(IGFRs) 1 item
  50. CGRP receptors 1 item
  51. Pim 1 item
  52. GABAB Receptors 1 item
  53. Liver X receptors (LXRs) 1 item
  54. Glucagon-like peptide 1 (GLP-1) receptors 2item
  55. Sir2-like Family Deacetylases (Sirtuins) 3item
  56. Voltage-gated Sodium (NaV) Channels 1 item
  57. Deubiquitinating enzymes (DUBs) 1 item
  58. PP1 1 item
  59. PP2A 1 item
  60. Smoothened 2item
  61. Eukaryotic elongation factors 1 item
  62. MET 1 item
  63. Src 6item
  64. Trk Receptors 3item
  65. Aminopeptidases 3item
  66. NMDA Receptors 2item
  67. STAT 7item
  68. Microtubules/Tubulins 3item
  69. Estrogen and Related Receptors 2item
  70. EGFR 4item
  71. Hedgehog 1 item
  72. ROCK 2item
  73. BTK 1 item
  74. RIP kinases 1 item
  75. PAK 1 item
  76. Hypoxia Inducible Factors (HIFs) 1 item
  77. BMP and Other Activin Receptors 2item
  78. JAK 9item
  79. p300 1 item
  80. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  81. Syk 3item
  82. Progesterone Receptors 1 item
  83. EZH1 1 item
  84. DNA-PK 6item
  85. HSP90 2item
  86. AMPK 1 item
  87. Gutathione S-transferase 1 item
  88. CCR 2item
  89. TNKS 1 item
  90. Topoisomerases 5item
  91. Cytochrome P450 (CYP450) 4item
  92. Toll-like receptors (TLRs) 3item
  93. DNA Methyltransferases 2item
  94. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  95. ERK 5item
  96. HMG-CoA Reductases 1 item
  97. c-MET 3item
  98. BMI-1 1 item
  99. PKC 8item
  100. Calpains 2item
  101. M1 Receptors 1 item
  102. HCV Proteases 1 item
  103. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  104. Protease-Activated Receptors 1 item
  105. RAD51 1 item
  106. 5-HT2 Receptors 3item
  107. LRRK2 2item
  108. Calcium chelator 1 item
  109. DGAT 2item
  110. Insulin and Insulin-like Receptors 2item
  111. PARP 5item
  112. CB1 Receptors 2item
  113. Melanocortin (MC) Receptors 1 item
  114. ALK 2item
  115. Sphingosine kinases (SphKs) 2item
  116. Trypsin 1 item
  117. Chymotrypsin 1 item
  118. Kallikrein 1 item
  119. Trypsinogen 1 item
  120. Monocarboxylate transporters (MCTs) 2item
  121. PKG 1 item
  122. PKA 5item
  123. GPR30 1 item
  124. HIV-1 gp120 1 item
  125. D2 Receptors 1 item
  126. Lactate Dehydrogenases (LDH) 1 item
  127. MK2 1 item
  128. Fatty-acid-binding proteins (FABPs) 1 item
  129. Tie-2 2item
  130. RSK 1 item
  131. Free Fatty Acid Receptors 1 item
  132. phosphatases 1 item
  133. Autophagy 3item
  134. ATM/ATR 2item
  135. COX 6item
  136. YAP 1 item
  137. CK1 1 item
  138. CK2 1 item
  139. HIV Integrases 1 item
  140. Nampt 1 item
  141. P2X Receptors 1 item
  142. Glutaminases 1 item
  143. Carbonic Anhydrases 2item
  144. Ron 1 item
  145. BLM 1 item
  146. HSV 1 item
  147. NADPH Oxidases 1 item
  148. Calcium-activated chloride channels (CaCC) 1 item
  149. GPR35 1 item
  150. Aldehyde Dehydrogenases 1 item
  151. MAGL 1 item
  152. Leukotriene and Related Receptors 1 item
  153. Histamine H1 Receptors 2item
  154. Inositol-requiring enzyme 1 (IRE1) 1 item
  155. Na /K /Cl- Symporters (NKCCs) 1 item
  156. TRP Channel 2item
  157. RNA Polymerases 1 item
  158. Norepinephrine transporter 1 item
  159. 5-HT Transporters 1 item
  160. Guanylyl Cyclases 1 item
  161. Histone Demethylases 1 item
  162. MNK 2item
  163. NO Donors / Precursors 1 item
  164. CB2 Receptors 1 item
  165. HIV-1 reverse transcriptase 1 item
  166. IL Receptors 1 item
  167. 15-lipoxygenases 1 item
  168. AChE 1 item
  169. Insulin Receptors 1 item
  170. IRG-1R 1 item
  171. eEF-2 1 item
  172. CRTH2 1 item
  173. Nuclear Receptors 1 item
  174. ZAP-70 1 item
  175. Angiotensin AT1 Receptors 2item
  176. Protein Arginine Methyltransferases 1 item
  177. Na /Ca2 Exchangers (NCXs) 1 item
  178. Ubiquitin-activating Enzyme E1 1 item
  179. BACE 1 item
  180. Glucagon Receptors 1 item
  181. PP4 1 item
  182. c-RET 1 item
  183. Nonstructural protein 5B (NS5B) 1 item
  184. guanylyl cyclase 1 item
  185. ETA Receptors 2item
  186. ETB Receptors 1 item
  187. p70 rsk 3item
  188. voltage-gated chloride channels 1 item
  189. 5-HT1 Receptor 1 item
  190. VEGFR3/FLT4 1 item
  191. NTRK1/TRKA 1 item
  192. CSF-1R/c-Fms 1 item
  193. Tryptophan hydroxylases (TPH) 1 item
  194. NMPRTase 1 item
  195. Bfl-1 1 item
  196. KDR 1 item
  197. Fyn kinase 1 item
  198. p53 4item
  199. metalloprotease 1 item
  200. Antifungal 1 item
  201. 5-HT receptors 1 item
  202. sodium channel 1 item
  203. c-Fms tyrosine kinase 1 item
  204. Smoothened receptor 1 item
  205. PPAR 1 item
  206. IKK 1 item
  207. Ftase 1 item
  208. Elastases 1 item
  209. ATP synthase 1 item
  210. Vitamin D receptors (VDRs) 1 item
  211. Antibiotic 3item
  212. Mer tyrosine kinase 1 item
  213. Hec1 1 item
  214. Stem Cell Differentiation 1 item
  215. PP2A/Nkd interaction 1 item
  216. HMGCR 1 item
  217. HIV 1 item
  218. TRPA 1 item
  219. PDK-1 1 item
  220. Prk 1 item
  221. Trx 1 item
  222. Neurokinin receptor 1 item
  223. HSP70 1 item
  224. ICAM 1 item
  225. ITK 1 item
  226. Rho 1 item
  227. Aryl hydrocarbon receptors (AHRs) 1 item
  228. Ubiquitin E3 Ligases 1 item
  229. DCLK2 1 item
  230. integrase 1 item
  231. NOS 1 item
  232. GPR3 1 item
  233. Adenosine Deaminases 1 item
  234. mitochondrial pyruvate carrier (MPC) 1 item
  235. DNA gyrase 1 item
  236. Thrombin Receptor 1 item
  237. prolactin secretion 1 item
  238. gonadotropin release 1 item
  239. DprE 1 item
  240. Vitamin D 1 item
  241. Flk1 1 item
  242. SAPK 1 item
  243. p21 1 item
  244. Prostaglandin synthesis 1 item
  245. glutamate release 1 item
  246. Aromatases 1 item
  247. 5-HT 1 item
  248. TRPC channel 1 item
  249. PKD 1 item
  250. FKBP 1 item
  251. MCL1 1 item
  252. Bcl-w 1 item
  253. ACE 1 item
  254. MST 1 item
  255. PPK 1 item
  256. c-Syk 1 item
  257. CDK1/CyclinB 1 item
  258. Tph 1 item
  259. reverse transcriptase 1 item
  260. Cholesterol absorption 1 item
  261. Substance P/NK1 Receptor 1 item
  262. gp120/CD4 1 item
  263. ATM 1 item
  264. PTEN 1 item
  265. NS3/4a Proteases 1 item
  266. p90 S6K 1 item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acute Disseminated Candidiasis 1 item
  3. Acute Lung Injury 1 item
  4. Acute Myelogenous Leukemia 1 item
  5. Acute Myeloid Leukemia 9item
  6. Adrenocortical Carcinoma 1 item
  7. Advanced Renal Cell Carcinoma 1 item
  8. Autoimmune Diseases 1 item
  9. Biliary Cancer 1 item
  10. Bladder Cancer 3item
  11. Bladder Carcinoma 1 item
  12. Bladder Diseases 1 item
  13. Brain Injuries Studies 1 item
  14. Breast Cancer 56item
  15. Cancer 249item
  16. Candida Peritonitis 1 item
  17. Candidemia 1 item
  18. Cervical Cancer 4item
  19. Cholangiocarcinoma 1 item
  20. Chronic Lymphocytic Leukemia 3item
  21. Clear Cell Renal Cell Carcinoma 1 item
  22. Colon Cancer 20item
  23. Colon Carcinoma 5item
  24. Colorectal Cancer 24item
  25. Diabetes 1 item
  26. Epilepsy 3item
  27. Fungal Infection 1 item
  28. Glioblastoma 17item
  29. Glioma 10item
  30. HCV 1 item
  31. Heart Failure 3item
  32. Hepatic Cancer 1 item
  33. Hepatitis C 2item
  34. Hepatocellular Carcinoma 3item
  35. HIV 7item
  36. HIV Infections 4item
  37. Hypercholesterolemia 2item
  38. Inflammatory Diseases 9item
  39. Leukemia 14item
  40. Liver Cancer 1 item
  41. Lung Cancer 18item
  42. Lung Carcinoma 2item
  43. Lymphoma 13item
  44. Medulloblastoma 1 item
  45. Melanoma 19item
  46. Mixed Lineage Leukemia 1 item
  47. Multiple Myeloma 6item
  48. Myelofibrosis 1 item
  49. Myeloma 3item
  50. Neuroblastoma 4item
  51. Non-small Cell Lung Cancer 15item
  52. Non-small Cell Lung Carcinoma 1 item
  53. Osteoporosis 1 item
  54. Ovarian Cancer 18item
  55. Pancreatic Cancer 25item
  56. Pancreatic Carcinoma 3item
  57. Pentacyclic Triterpenoid 1 item
  58. Prostate Cancer 28item
  59. Psoriasis 1 item
  60. Pulmonary Arterial Hypertension 1 item
  61. Pulmonary Fibrosis 1 item
  62. Renal Cancer 3item
  63. Renal Cell Carcinoma 4item
  64. Rheumatoid Arthritis 6item
  65. Schizophrenia 1 item
  66. Sleep Disorders 1 item
  67. Squamous Cell Carcinoma 1 item
  68. Testicular Cancer 1 item
  69. Thyroid Cancer 4item
  70. Tuberculosis 4item
  71. Type 2 Diabetes 9item