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  • Search results for: 'research area pi3k akt signaling pdk 1'

Search results for: 'research area pi3k akt signaling pdk 1'

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  1. AKT inhibitor VIII
    A3149 AKT inhibitor VIII
     2 Citation
    Target: Akt
    Summary: Allosteric Akt kinase inhibitor
      insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL
  2. Torin 1
    A8312 Torin 1
     7 Citation
    Target: mTOR
    Summary: MTOR inhibitor,potent and selective
  3. GDC-0068 (RG7440)
    A3006 GDC-0068 (RG7440)
    Target: Akt
    Summary: Pan-AKT inhibitor,highly selective
      ≥22.9 mg/mL
  4. CCT128930 HCl
    A8617 CCT128930 HCl
    Target: Akt
    Summary: AKT inhibitor
      insoluble in H2O; ≥17.1 mg/mL
  5. BKM120
    A3015 BKM120
     1 Citation
    Target: PI3K
    Summary: Inhibitor of pan-Class I PI3K
      ≥20.52 mg/mL
  6. XL147
    A5112 XL147
    Target: PI3K
    Summary: PI3K inhibitor,selective and reversible
      ≥22.45 mg/mL
  7. PP242
    A8318 PP242
    Target: mTOR
    Summary: MTOR inhibitor, selective and ATP-competitive
  8. Everolimus (RAD001)
    A8169 Everolimus (RAD001)
     8 Citation
    Target: mTOR
    Summary: MTOR inhibitor
      ≥47.91 mg/mL
  9. AS-605240
    A5176 AS-605240
    Target: PI3K
    Summary: Potent and selective PI 3-Kγ inhibitor
      insoluble in H2O; insoluble in EtOH; ≥4.28 mg/mL
  10. AZD8055
    A8214 AZD8055
     2 Citation
    Target: mTOR
    Summary: MTOR inhibitor
      ≥23.3 mg/mL

Items 1-10 of 388

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Category
  1. Proteases 31item
  2. Apoptosis 25item
  3. Chromatin/Epigenetics 39item
  4. Metabolism 19item
  5. MAPK Signaling 29item
  6. Tyrosine Kinase 47item
  7. DNA Damage/DNA Repair 27item
  8. PI3K/Akt/mTOR Signaling 45item
  9. Microbiology & Virology 15item
  10. Cell Cycle/Checkpoint 32item
  11. Ubiquitination/ Proteasome 8item
  12. JAK/STAT Signaling 15item
  13. TGF-β / Smad Signaling 17item
  14. Angiogenesis 3item
  15. GPCR/G protein 19item
  16. Stem Cell 22item
  17. Membrane Transporter/Ion Channel 9item
  18. Endocrinology and Hormones 9item
  19. Neuroscience 18item
  20. Obesity, Appetite Control & Diabetes 2item
  21. Other Signal Transduction 3item
  22. Others 25item
  23. Immunology/Inflammation 10item
  24. Cardiovascular 1 item
Reversibility
  1. Reversible 16item
  2. Irreversible 6item
Target
  1. Caspases 5item
  2. Cyclin-Dependent Kinases 12item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 1 item
  5. Cathepsins 3item
  6. Histone Deacetylases (HDACs) 9item
  7. Inhibitor of apoptosis proteins (IAP) 1 item
  8. Akt 5item
  9. Bcl-2 6item
  10. PI3K 25item
  11. CXCR 1 item
  12. Raf 7item
  13. Aurora Kinases 5item
  14. Bcl-xl 2item
  15. CSF-1R 1 item
  16. Gap Junctions 1 item
  17. MDM2 1 item
  18. EZH2 3item
  19. mTOR 13item
  20. Bromodomains 1 item
  21. AP-1 3item
  22. MMP 8item
  23. Androgen Receptors 4item
  24. Acyl coenzyme A: cholesterol acyltransferases 1 item
  25. FLT3 9item
  26. GSK-3 7item
  27. Factor Xa 1 item
  28. LPA Receptors 1 item
  29. P-glycoprotein (P-gp) 1 item
  30. PLK 4item
  31. Chk 4item
  32. VEGFR 17item
  33. PDGFR 11item
  34. c-Kit 4item
  35. RET 2item
  36. IRAK 2item
  37. Bromodomain-containing proteins(BRDs) 1 item
  38. Phosphodiesterases (PDEs) 1 item
  39. Mcl-1 5item
  40. p38 5item
  41. PKB 1 item
  42. JNK 4item
  43. SGK 2item
  44. Bcr-Abl 5item
  45. MEK 10item
  46. PORCN 1 item
  47. DOT1L 1 item
  48. FGFR 3item
  49. Insulin-like growth factor receptors(IGFRs) 1 item
  50. CGRP receptors 1 item
  51. Pim 2item
  52. GABAB Receptors 1 item
  53. Glucagon-like peptide 1 (GLP-1) receptors 2item
  54. Sir2-like Family Deacetylases (Sirtuins) 2item
  55. Deubiquitinating enzymes (DUBs) 1 item
  56. PP1 1 item
  57. PP2A 1 item
  58. Smoothened 2item
  59. Eukaryotic elongation factors 1 item
  60. MET 1 item
  61. Src 5item
  62. Trk Receptors 3item
  63. Aminopeptidases 2item
  64. STAT 5item
  65. Microtubules/Tubulins 4item
  66. EGFR 4item
  67. Hedgehog 1 item
  68. Reverse Transcriptases 1 item
  69. ROCK 2item
  70. BTK 1 item
  71. RIP kinases 1 item
  72. PAK 1 item
  73. Hypoxia Inducible Factors (HIFs) 1 item
  74. BMP and Other Activin Receptors 2item
  75. JAK 6item
  76. p300 1 item
  77. Syk 3item
  78. Progesterone Receptors 1 item
  79. EZH1 1 item
  80. DNA-PK 5item
  81. HSP90 2item
  82. AMPK 1 item
  83. Gutathione S-transferase 1 item
  84. CCR 2item
  85. eIF4E/eIF3G interaction 1 item
  86. TNKS 1 item
  87. Topoisomerases 3item
  88. Cytochrome P450 (CYP450) 3item
  89. Ferroptosis 1 item
  90. Toll-like receptors (TLRs) 2item
  91. Actin 1 item
  92. DNA Methyltransferases 1 item
  93. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  94. ERK 4item
  95. HMG-CoA Reductases 1 item
  96. Vacuolar-type ATPase 1 item
  97. c-MET 3item
  98. BMI-1 1 item
  99. PKC 4item
  100. Calpains 2item
  101. HCV Proteases 1 item
  102. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  103. Protease-Activated Receptors 1 item
  104. USP 1 item
  105. 5-HT2 Receptors 3item
  106. LRRK2 2item
  107. Calcium chelator 1 item
  108. DGAT 2item
  109. Insulin and Insulin-like Receptors 2item
  110. PARP 2item
  111. CB1 Receptors 1 item
  112. Melanocortin (MC) Receptors 1 item
  113. ALK 1 item
  114. Sphingosine kinases (SphKs) 1 item
  115. Trypsin 1 item
  116. Chymotrypsin 1 item
  117. Kallikrein 1 item
  118. Trypsinogen 1 item
  119. Monocarboxylate transporters (MCTs) 1 item
  120. GPR30 1 item
  121. HIV-1 gp120 1 item
  122. D2 Receptors 1 item
  123. TBK1 1 item
  124. MARK1 1 item
  125. NUAK1 1 item
  126. Lactate Dehydrogenases (LDH) 1 item
  127. MK2 2item
  128. Fatty-acid-binding proteins (FABPs) 1 item
  129. Tie-2 2item
  130. Free Fatty Acid Receptors 1 item
  131. phosphatases 1 item
  132. Autophagy 2item
  133. ATM/ATR 3item
  134. COX 4item
  135. YAP 1 item
  136. CK1 1 item
  137. Cryptochromes 1 item
  138. G-quadruplexes 1 item
  139. NAT10 1 item
  140. Nampt 1 item
  141. P2X Receptors 1 item
  142. Glutaminases 1 item
  143. Carbonic Anhydrases 2item
  144. Ron 1 item
  145. BLM 1 item
  146. HSV 1 item
  147. Calcium-activated chloride channels (CaCC) 1 item
  148. GPR35 1 item
  149. Aldehyde Dehydrogenases 1 item
  150. Synthases/Synthetases 1 item
  151. MAGL 1 item
  152. c-Fyn 1 item
  153. Leukotriene and Related Receptors 1 item
  154. Histamine H1 Receptors 1 item
  155. Inositol-requiring enzyme 1 (IRE1) 1 item
  156. SETD7 1 item
  157. TRP Channel 2item
  158. RNA Polymerases 1 item
  159. Norepinephrine transporter 1 item
  160. 5-HT Transporters 1 item
  161. Guanylyl Cyclases 1 item
  162. Histone Demethylases 1 item
  163. MNK 1 item
  164. NO Donors / Precursors 1 item
  165. CB2 Receptors 1 item
  166. HIV-1 reverse transcriptase 1 item
  167. IL Receptors 1 item
  168. 15-lipoxygenases 1 item
  169. Insulin Receptors 1 item
  170. IRG-1R 1 item
  171. eEF-2 1 item
  172. Inward Rectifier Potassium (Kir) Channels 1 item
  173. CRTH2 1 item
  174. Nuclear Receptors 1 item
  175. ZAP-70 1 item
  176. Angiotensin AT1 Receptors 2item
  177. Protein Arginine Methyltransferases 1 item
  178. Na /Ca2 Exchangers (NCXs) 1 item
  179. Glucagon Receptors 1 item
  180. PP4 1 item
  181. c-RET 1 item
  182. Nonstructural protein 5B (NS5B) 1 item
  183. ETA Receptors 2item
  184. ETB Receptors 1 item
  185. p70 rsk 1 item
  186. Protein polybromo-1 1 item
  187. SMARCA4 1 item
  188. SMARCA2 1 item
  189. c-Fms tyrosine kinase 1 item
  190. IKK 1 item
  191. Ftase 1 item
  192. Elastases 1 item
  193. telomerase 1 item
  194. ITK 1 item
  195. NOD1 1 item
  196. DCLK2 1 item
  197. Lck 1 item
  198. Aromatases 1 item
  199. PKD 1 item
  200. MCL1 1 item
  201. Bcl-w 1 item
  202. MST 1 item
  203. Substance P/NK1 Receptor 1 item
  204. gp120/CD4 1 item
  205. ATM 2item
Reported Experiments
  1. Animal Experiments 333item
  2. Cell Experiments 226item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acute Disseminated Candidiasis 1 item
  3. Acute Lung Injury 1 item
  4. Acute Myelogenous Leukemia 1 item
  5. Acute Myeloid Leukemia 10item
  6. Adrenocortical Carcinoma 1 item
  7. Advanced Renal Cell Carcinoma 1 item
  8. Autoimmune Diseases 1 item
  9. Biliary Cancer 1 item
  10. Bladder Cancer 3item
  11. Bladder Carcinoma 1 item
  12. Bladder Diseases 1 item
  13. Brain Injuries Studies 1 item
  14. Breast Cancer 59item
  15. Cancer 211item
  16. Candida Peritonitis 1 item
  17. Candidemia 1 item
  18. Cervical Cancer 4item
  19. Cholangiocarcinoma 1 item
  20. Chronic Lymphocytic Leukemia 3item
  21. Clear Cell Renal Cell Carcinoma 1 item
  22. Colon Cancer 21item
  23. Colon Carcinoma 5item
  24. Colorectal Cancer 25item
  25. Diabetes 3item
  26. Epilepsy 2item
  27. Fungal Infection 1 item
  28. Glioblastoma 18item
  29. Glioma 10item
  30. Hepatic Cancer 1 item
  31. Hepatitis C 2item
  32. Hepatocellular Carcinoma 3item
  33. HIV 4item
  34. HIV Infections 4item
  35. Hypercholesterolemia 1 item
  36. Inflammatory Diseases 9item
  37. Leukemia 11item
  38. Liver Cancer 1 item
  39. Lung Cancer 19item
  40. Lung Carcinoma 2item
  41. Lymphoma 15item
  42. Medulloblastoma 1 item
  43. Melanoma 18item
  44. Mixed Lineage Leukemia 1 item
  45. Multiple Myeloma 7item
  46. Myelofibrosis 1 item
  47. Myeloma 3item
  48. Neuroblastoma 4item
  49. Non-small Cell Lung Cancer 15item
  50. Non-small Cell Lung Carcinoma 1 item
  51. Osteoporosis 1 item
  52. Ovarian Cancer 18item
  53. Pancreatic Cancer 25item
  54. Pancreatic Carcinoma 3item
  55. Prostate Cancer 32item
  56. Psoriasis 1 item
  57. Pulmonary Arterial Hypertension 1 item
  58. Pulmonary Fibrosis 1 item
  59. Renal Cancer 3item
  60. Renal Cell Carcinoma 4item
  61. Rheumatoid Arthritis 6item
  62. Schizophrenia 1 item
  63. Sleep Disorders 1 item
  64. Squamous Cell Carcinoma 1 item
  65. Testicular Cancer 1 item
  66. Thyroid Cancer 4item
  67. Tuberculosis 1 item
  68. Type 2 Diabetes 10item