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  • Search results for: 'research area pi3k akt signaling pdk 1'

Search results for: 'research area pi3k akt signaling pdk 1'

Items 41-50 of 88

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  1. Marinopyrrole A
    B1080 Marinopyrrole A
    Target: Mcl-1
    Summary: Selective Mcl-1 inhibitor
      Soluble in DMSO
  2. VX-765
    A8238 VX-765
     1 Citation
    Target: Caspases
    Summary: Caspase-1 inhibitor,potent and selective
      insoluble in H2O; ≥313 mg/mL
  3. Boc-D-FMK
    A1904 Boc-D-FMK
     1 Citation
    Target: Caspases
    Summary: Pan-caspase inhibitor
      insoluble in H2O; ≥11.65 mg/mL
  4. Selonsertib (GS-4997)
    B7812 Selonsertib (GS-4997)
    Summary: apoptosis signal-regulating kinase 1 (ASK1) inhibitor
      ≥44.5 mg/mL
  5. Necrostatin 2
    A3652 Necrostatin 2
     2 Citation
    Summary: In vitro necroptosis inhibitor
      Soluble in DMSO
  6. Plumbagin
    A4456 Plumbagin
    Summary: Anticancer agent
  7. Regorafenib
    A8236 Regorafenib
     4 Citation
    Target: Raf|VEGFR|PDGFR|c-Kit|RET
    Summary: Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1
      ≥25.04 mg/mL
  8. NSC59984
    B6045 NSC59984
    Summary: Restores the p53 signaling pathway
      Soluble in DMSO
  9. TW-37
    A4234 TW-37
     1 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor, inhibits Bcl-2,Bcl-XL and Mcl-1
      insoluble in H2O; ≥19.75 mg/mL
  10. R-7050
    C3129 R-7050
    Summary: TNF-α receptor signaling antagonist,cell-permeable
      insoluble in H2O; ≥17.67 mg/mL

Items 41-50 of 88

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  1. Category Apoptosis Remove This Item
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  1. Caspase 9item
  2. 14.3.3 Proteins 1 item
  3. Apoptosis Inducers 15item
  4. Bax 2item
  5. Bcl-2 Family 20item
  6. Bcl-xL 5item
  7. c-RET 4item
  8. IAP 4item
  9. KEAP1-Nrf2 2item
  10. MDM2 6item
  11. p53 12item
  12. PC-PLC 1 item
  13. PKD 2item
  14. RasGAP (Ras- P21) 1 item
  15. Thymidylate Synthase 1 item
  16. TNF-α 6item
  17. Other Apoptosis 2item
  18. APC 1 item
  19. PD-1/PD-L1 interaction 3item
  20. ASK1 2item
  21. PAR4 1 item
Specificity
  1. Selective 25item
Reversibility
  1. Irreversible 3item
Target
  1. Caspases 6item
  2. Proteasome 1 item
  3. Inhibitor of apoptosis proteins (IAP) 1 item
  4. Bcl-2 8item
  5. Raf 1 item
  6. Bcl-xl 2item
  7. MDM2 1 item
  8. VEGFR 2item
  9. PDGFR 2item
  10. c-Kit 1 item
  11. RET 1 item
  12. Mcl-1 7item
  13. Bcr-Abl 1 item
  14. Sir2-like Family Deacetylases (Sirtuins) 1 item
  15. Aminopeptidases 1 item
  16. RIP kinases 1 item
  17. PD-1/PD-L1 interaction 1 item
  18. Topoisomerases 1 item
  19. Autophagy 1 item
  20. Bfl-1 1 item
  21. p53 3item
  22. Nrf2/ARE signal 1 item
  23. PPAR 1 item
  24. HIV 1 item
  25. HSP70 1 item
  26. Ubiquitin E3 Ligases 1 item
  27. p21 1 item
  28. PKD 1 item
  29. MCL1 1 item
  30. Bcl-w 1 item
  31. NS3/4a Proteases 1 item
Reported Experiments
  1. Animal Experiments 35item
  2. Cell Experiments 29item
Related Disease
  1. Acute Myeloid Leukemia 1 item
  2. Autoimmune Diseases 1 item
  3. Breast Cancer 4item
  4. Cancer 21item
  5. Chronic Lymphocytic Leukemia 1 item
  6. Colorectal Cancer 2item
  7. Glioblastoma 1 item
  8. HCV 1 item
  9. Inflammatory Diseases 1 item
  10. Lung Cancer 1 item
  11. Lymphoma 2item
  12. Melanoma 1 item
  13. Multiple Myeloma 1 item
  14. Myeloma 1 item
  15. Non-small Cell Lung Cancer 1 item
  16. Ovarian Cancer 1 item
  17. Pancreatic Cancer 2item
  18. Pentacyclic Triterpenoid 1 item
  19. Prostate Cancer 3item
  20. Rheumatoid Arthritis 1 item
  21. Testicular Cancer 1 item