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  • Search results for: 'research area pi3k akt signaling pdk 1'

Search results for: 'research area pi3k akt signaling pdk 1'

Items 51-60 of 88

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  1. MIM1
    A4465 MIM1
     1 Citation
    Target: Mcl-1
    Summary: Mcl-1 Inhibitor
      insoluble in EtOH; insoluble in H2O; ≥12.15 mg/mL
  2. Sulforaphane
    C4733 Sulforaphane
    Summary: inducer of chemopreventative enzymes via Keap1-Nrf2 signaling
      ≥51.6 mg/mL
  3. Sabutoclax
    A4199 Sabutoclax
     2 Citation
    Target: Bcl-2|Mcl-1|Bfl-1
    Summary: pan-Bcl-2 inhibitor
      insoluble in H2O; ≥205.6 mg/mL
  4. VU661013
    A8783 VU661013
    Summary: Novel, potent, selective MCL-1 inhibitor
      ≥125 mg/mL
  5. AT-101
    A3196 AT-101
    Target: NS3/4a Proteases
    Summary: BH3-mimetic,gossypol enantiomer
      ≥20.7 mg/mL
  6. SU5416
    A3847 SU5416
    Target: VEGFR
    Summary: VEGF receptor inhibitor and AHR agonist
      insoluble in EtOH; insoluble in H2O; ≥11.9 mg/mL
  7. PRIMA-1MET
    A4484 PRIMA-1MET
    Summary: Restore mutant p53 activity, induce BAX and PUMA
  8. Gambogic Acid
    A3424 Gambogic Acid
    Summary: Caspase activator and apoptosis inducer
      ≥22.45 mg/mL
  9. 5,7-dihydroxychromone
    N2172 5,7-dihydroxychromone
     1 Citation
    Target: Nrf2/ARE signal|PPAR
    Summary: Nrf2/ARE signal activator and PPARγ agonist
  10. ABT-737
    A8193 ABT-737
     14 Citation
    Summary: Bcl-2 inhibitor
      ≥40.67 mg/mL

Items 51-60 of 88

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  1. Caspase 9item
  2. 14.3.3 Proteins 1 item
  3. Apoptosis Inducers 15item
  4. Bax 2item
  5. Bcl-2 Family 20item
  6. Bcl-xL 5item
  7. c-RET 4item
  8. IAP 4item
  9. KEAP1-Nrf2 2item
  10. MDM2 6item
  11. p53 12item
  12. PC-PLC 1 item
  13. PKD 2item
  14. RasGAP (Ras- P21) 1 item
  15. Thymidylate Synthase 1 item
  16. TNF-α 6item
  17. Other Apoptosis 2item
  18. APC 1 item
  19. PD-1/PD-L1 interaction 3item
  20. ASK1 2item
  21. PAR4 1 item
Specificity
  1. Selective 25item
Reversibility
  1. Irreversible 3item
Target
  1. Caspases 6item
  2. Proteasome 1 item
  3. Inhibitor of apoptosis proteins (IAP) 1 item
  4. Bcl-2 8item
  5. Raf 1 item
  6. Bcl-xl 2item
  7. MDM2 1 item
  8. VEGFR 2item
  9. PDGFR 2item
  10. c-Kit 1 item
  11. RET 1 item
  12. Mcl-1 7item
  13. Bcr-Abl 1 item
  14. Sir2-like Family Deacetylases (Sirtuins) 1 item
  15. Aminopeptidases 1 item
  16. RIP kinases 1 item
  17. PD-1/PD-L1 interaction 1 item
  18. Topoisomerases 1 item
  19. Autophagy 1 item
  20. Bfl-1 1 item
  21. p53 3item
  22. Nrf2/ARE signal 1 item
  23. PPAR 1 item
  24. HIV 1 item
  25. HSP70 1 item
  26. Ubiquitin E3 Ligases 1 item
  27. p21 1 item
  28. PKD 1 item
  29. MCL1 1 item
  30. Bcl-w 1 item
  31. NS3/4a Proteases 1 item
Reported Experiments
  1. Animal Experiments 35item
  2. Cell Experiments 29item
Related Disease
  1. Acute Myeloid Leukemia 1 item
  2. Autoimmune Diseases 1 item
  3. Breast Cancer 4item
  4. Cancer 21item
  5. Chronic Lymphocytic Leukemia 1 item
  6. Colorectal Cancer 2item
  7. Glioblastoma 1 item
  8. HCV 1 item
  9. Inflammatory Diseases 1 item
  10. Lung Cancer 1 item
  11. Lymphoma 2item
  12. Melanoma 1 item
  13. Multiple Myeloma 1 item
  14. Myeloma 1 item
  15. Non-small Cell Lung Cancer 1 item
  16. Ovarian Cancer 1 item
  17. Pancreatic Cancer 2item
  18. Pentacyclic Triterpenoid 1 item
  19. Prostate Cancer 3item
  20. Rheumatoid Arthritis 1 item
  21. Testicular Cancer 1 item