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  • Search results for: 'research area pi3k akt signaling pdk 1'

Search results for: 'research area pi3k akt signaling pdk 1'

Items 1-10 of 118

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  1. AMI-1
    A1908 AMI-1
    Summary: PRMT1 inhibitor
      insoluble in EtOH; insoluble in DMSO; ≥19.1 mg/mL
  2. JANEX-1
    A3515 JANEX-1
    Summary: JAK3 inhibitor
      insoluble in EtOH; ≥11.65 mg/mL
  3. TCS PIM-1 1
    A4521 TCS PIM-1 1
    Summary: Pim-1 kinase inhibitor,ATP-competitve
      insoluble in H2O; insoluble in EtOH; ≥12.8 mg/mL
  4. Tenovin-1
    A4203 Tenovin-1
    Target: Sir2-like Family Deacetylases (Sirtuins)|p53|p21
    Summary: SIRT2 inhibitor, activates p53
      insoluble in H2O; insoluble in EtOH; ≥15 mg/mL
  5. PIM-1 Inhibitor 2
    A4519 PIM-1 Inhibitor 2
    Summary: Potent Pim-1 kinase inhibitor
      Soluble in DMSO
  6. Sephin1
    A8708 Sephin1
     1 Citation
    Target: phosphatases
    Summary: Selective PPP1R15A inhibitor
      insoluble in H2O; insoluble in EtOH; ≥7.75 mg/mL
  7. OF-1
    B4895 OF-1
    Summary: BRPF1B and BRPF2 bromodomain inhibitor
      insoluble in H2O; insoluble in EtOH; ≥14.55 mg/mL
  8. ITSA-1 (ITSA1)
    B7816 ITSA-1 (ITSA1)
    Summary: HDAC activator via Trichostatin A (TSA) suppression
      insoluble in H2O; insoluble in EtOH; ≥89 mg/mL
  9. RN-1 (hydrochloride)
    C4247 RN-1 (hydrochloride)
    Summary: LSD1 inhibitor
      insoluble in EtOH; ≥2.7 mg/mL
  10. PFI-1 (PF-6405761)
    A4184 PFI-1 (PF-6405761)
     1 Citation
    Target: Bromodomains
    Summary: BET inhibitor
      insoluble in H2O; insoluble in EtOH; ≥128.4 mg/mL

Items 1-10 of 118

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  1. Category Chromatin/Epigenetics Remove This Item
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Category
  1. Bromodomain 8item
  2. Aurora Kinase 7item
  3. HDAC 16item
  4. Histone Acetyltransferases 3item
  5. Histone Demethylases 7item
  6. Histone Methyltransferase 9item
  7. HIF 6item
  8. JAK 19item
  9. PARP 17item
  10. Pim 7item
  11. Protein Ser/Thr Phosphatases 13item
  12. Sirtuin 5item
  13. Polycomb repressive complex 1 item
Specificity
  1. Selective 39item
Reversibility
  1. Reversible 1 item
  2. Irreversible 1 item
Target
  1. Histone Deacetylases (HDACs) 11item
  2. PI3K 1 item
  3. Aurora Kinases 6item
  4. MDM2 1 item
  5. EZH2 1 item
  6. Bromodomains 3item
  7. FLT3 3item
  8. VEGFR 1 item
  9. RET 1 item
  10. MEK 1 item
  11. DOT1L 1 item
  12. Pim 2item
  13. Sir2-like Family Deacetylases (Sirtuins) 3item
  14. PP1 1 item
  15. PP2A 1 item
  16. Src 2item
  17. STAT 2item
  18. Hypoxia Inducible Factors (HIFs) 1 item
  19. JAK 9item
  20. p300 1 item
  21. TNKS 1 item
  22. Topoisomerases 1 item
  23. DNA Methyltransferases 1 item
  24. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  25. PARP 5item
  26. phosphatases 1 item
  27. NAT10 1 item
  28. SETD7 1 item
  29. Histone Demethylases 1 item
  30. MNK 1 item
  31. Protein Arginine Methyltransferases 1 item
  32. PP4 1 item
  33. c-RET 1 item
  34. VEGFR3/FLT4 1 item
  35. NTRK1/TRKA 1 item
  36. CSF-1R/c-Fms 1 item
  37. Protein polybromo-1 1 item
  38. SMARCA4 1 item
  39. SMARCA2 1 item
  40. p53 2item
  41. Trx 1 item
  42. L3MBTL 1 item
  43. Lck 1 item
  44. p21 1 item
  45. 5-HT 1 item
Reported Experiments
  1. Animal Experiments 45item
  2. Cell Experiments 36item
Related Disease
  1. Acute Myeloid Leukemia 2item
  2. Breast Cancer 7item
  3. Cancer 32item
  4. Cervical Cancer 1 item
  5. Colon Cancer 4item
  6. Colon Carcinoma 1 item
  7. Colorectal Cancer 1 item
  8. Diabetes 1 item
  9. Epilepsy 1 item
  10. Glioblastoma 1 item
  11. Glioma 1 item
  12. Hepatic Cancer 1 item
  13. Hepatocellular Carcinoma 1 item
  14. Inflammatory Diseases 1 item
  15. Leukemia 2item
  16. Lung Cancer 1 item
  17. Lymphoma 2item
  18. Melanoma 1 item
  19. Mixed Lineage Leukemia 1 item
  20. Multiple Myeloma 2item
  21. Myelofibrosis 1 item
  22. Non-small Cell Lung Cancer 3item
  23. Ovarian Cancer 3item
  24. Pancreatic Cancer 2item
  25. Prostate Cancer 5item
  26. Renal Cell Carcinoma 1 item
  27. Rheumatoid Arthritis 1 item