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  • Search results for: 'research area pi3k akt signaling pdk 1'

Search results for: 'research area pi3k akt signaling pdk 1'

Items 131-140 of 509

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  1. WYE-125132 (WYE-132)
    B1642 WYE-125132 (WYE-132)
    Target: mTOR
    Summary: ATP-competitive mTOR inhibitor, highly potent
      insoluble in EtOH; insoluble in H2O; ≥13 mg/mL
  2. WR 1065
    A4487 WR 1065
    Summary: P53/p21waf-1/MDM2 activator
      ≥26.7 mg/mL
  3. GSK2126458
    A8556 GSK2126458
     1 Citation
    Target: PI3K|mTOR
    Summary: PI3K/mTOR inhibitor
      ≥25.3 mg/mL
  4. Motesanib
    A3632 Motesanib
    Target: VEGFR
    Summary: Inhibitor of Flk-1/Flt-4/PDGFR-/c-Kit
      ≥42 mg/mL
  5. Indomethacin
    A8449 Indomethacin
    Target: COX
    Summary: Cox inhibitor
  6. R406
    A8546 R406
     1 Citation
    Target: Syk
    Summary: SYK inhibitor,potent and ATP-competitive
      ≥31.45 mg/mL
  7. UNC2881
    B4357 UNC2881
    Target: Mer tyrosine kinase
    Summary: Mer tyrosine kinase inhibitor
      insoluble in H2O; insoluble in EtOH; ≥13.55 mg/mL
  8. Carbenoxolone disodium
    A8389 Carbenoxolone disodium
     1 Citation
    Target: Gap Junctions
    Summary: 11β-HSD inhibitor
      ≥30.74 mg/mL
  9. UK-5099
    A3899 UK-5099
     1 Citation
    Target: Monocarboxylate transporters (MCTs)|mitochondrial pyruvate carrier (MPC)
    Summary: MCTs and MPC inhibitor
      insoluble in EtOH; insoluble in H2O; ≥28.8 mg/mL
  10. CP-673451
    B2173 CP-673451
    Target: PDGFR
    Summary: PDGFRα/β inhibitor,potent and selective

Items 131-140 of 509

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  1. Signaling Pathways 486item
  2. Natural Products 10item
  3. Other Products 1 item
  4. Peptides 1 item
  5. Probes & Dyes 2item
  6. Peptides & Proteins 1 item
  7. Lab Reagents 9item
Specificity
  1. Selective 344item
  2. Non-Selective 2item
Reversibility
  1. Reversible 18item
  2. Irreversible 9item
Target
  1. Caspases 5item
  2. Cyclin-Dependent Kinases 11item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 1 item
  5. Cathepsins 3item
  6. Histone Deacetylases (HDACs) 11item
  7. Inhibitor of apoptosis proteins (IAP) 1 item
  8. Akt 12item
  9. Bcl-2 8item
  10. PI3K 32item
  11. CXCR 1 item
  12. Raf 9item
  13. Aurora Kinases 5item
  14. Bcl-xl 2item
  15. CSF-1R 1 item
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  18. EZH2 1 item
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  20. Bromodomains 2item
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  22. MMP 6item
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  24. Acyl coenzyme A: cholesterol acyltransferases 1 item
  25. FLT3 11item
  26. GSK-3 8item
  27. Factor Xa 1 item
  28. LPA Receptors 3item
  29. P-glycoprotein (P-gp) 1 item
  30. PLK 6item
  31. Chk 3item
  32. VEGFR 24item
  33. PDGFR 14item
  34. c-Kit 6item
  35. RET 3item
  36. IRAK 1 item
  37. Bromodomain-containing proteins(BRDs) 1 item
  38. Phosphodiesterases (PDEs) 2item
  39. Mcl-1 6item
  40. p38 6item
  41. PKB 1 item
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  46. PORCN 1 item
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  48. FGFR 4item
  49. Insulin-like growth factor receptors(IGFRs) 1 item
  50. CGRP receptors 1 item
  51. Pim 1 item
  52. GABAB Receptors 1 item
  53. Liver X receptors (LXRs) 1 item
  54. Glucagon-like peptide 1 (GLP-1) receptors 2item
  55. Sir2-like Family Deacetylases (Sirtuins) 3item
  56. Voltage-gated Sodium (NaV) Channels 1 item
  57. Deubiquitinating enzymes (DUBs) 1 item
  58. PP1 1 item
  59. PP2A 1 item
  60. Smoothened 2item
  61. Eukaryotic elongation factors 1 item
  62. MET 1 item
  63. Src 6item
  64. Trk Receptors 3item
  65. Aminopeptidases 3item
  66. NMDA Receptors 2item
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  70. EGFR 4item
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  74. BTK 1 item
  75. RIP kinases 1 item
  76. Monocyte chemotactic proteins 1 item
  77. PAK 1 item
  78. Hypoxia Inducible Factors (HIFs) 1 item
  79. BMP and Other Activin Receptors 2item
  80. JAK 9item
  81. p300 1 item
  82. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  83. Syk 3item
  84. Progesterone Receptors 1 item
  85. EZH1 1 item
  86. DNA-PK 6item
  87. HSP90 2item
  88. AMPK 1 item
  89. Gutathione S-transferase 1 item
  90. CCR 2item
  91. Angiotensin AT2 Receptors 1 item
  92. TNKS 1 item
  93. Topoisomerases 6item
  94. Cytochrome P450 (CYP450) 4item
  95. Toll-like receptors (TLRs) 3item
  96. Actin 1 item
  97. DNA Methyltransferases 2item
  98. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  99. ERK 6item
  100. HMG-CoA Reductases 1 item
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  102. BMI-1 1 item
  103. PKC 8item
  104. Calpains 2item
  105. M1 Receptors 1 item
  106. HCV Proteases 1 item
  107. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  108. O-GlcNAcase 1 item
  109. Protease-Activated Receptors 1 item
  110. RAD51 1 item
  111. 5-HT2 Receptors 3item
  112. LRRK2 2item
  113. Calcium chelator 1 item
  114. DGAT 2item
  115. Insulin and Insulin-like Receptors 2item
  116. PARP 6item
  117. CB1 Receptors 2item
  118. Melanocortin (MC) Receptors 1 item
  119. ALK 2item
  120. Sphingosine kinases (SphKs) 2item
  121. Trypsin 1 item
  122. Chymotrypsin 1 item
  123. Kallikrein 1 item
  124. Trypsinogen 1 item
  125. Monocarboxylate transporters (MCTs) 2item
  126. PKG 1 item
  127. PKA 5item
  128. GPR30 1 item
  129. HIV-1 gp120 1 item
  130. D2 Receptors 1 item
  131. Lactate Dehydrogenases (LDH) 1 item
  132. MK2 1 item
  133. Fatty-acid-binding proteins (FABPs) 1 item
  134. Tie-2 2item
  135. RSK 1 item
  136. Free Fatty Acid Receptors 1 item
  137. phosphatases 1 item
  138. Autophagy 3item
  139. ATM/ATR 2item
  140. COX 7item
  141. YAP 1 item
  142. CK1 1 item
  143. CK2 1 item
  144. HIV Integrases 1 item
  145. Pregnane X Receptors 1 item
  146. Nampt 1 item
  147. P2X Receptors 1 item
  148. Glutaminases 1 item
  149. Carbonic Anhydrases 2item
  150. Ron 1 item
  151. BLM 1 item
  152. HSV 1 item
  153. NADPH Oxidases 1 item
  154. Calcium-activated chloride channels (CaCC) 1 item
  155. GPR35 1 item
  156. Aldehyde Dehydrogenases 1 item
  157. MAGL 1 item
  158. Leukotriene and Related Receptors 1 item
  159. Histamine H1 Receptors 3item
  160. Na /K ATPases 1 item
  161. Inositol-requiring enzyme 1 (IRE1) 1 item
  162. Na /K /Cl- Symporters (NKCCs) 1 item
  163. Organic anion transporters (OATs) 1 item
  164. TRP Channel 3item
  165. RNA Polymerases 2item
  166. Norepinephrine transporter 1 item
  167. 5-HT Transporters 1 item
  168. Guanylyl Cyclases 1 item
  169. Histone Demethylases 1 item
  170. MNK 2item
  171. NO Donors / Precursors 1 item
  172. CB2 Receptors 1 item
  173. HIV-1 reverse transcriptase 1 item
  174. IL Receptors 1 item
  175. 15-lipoxygenases 1 item
  176. AChE 1 item
  177. Insulin Receptors 1 item
  178. IRG-1R 1 item
  179. eEF-2 1 item
  180. CRTH2 1 item
  181. Nuclear Receptors 1 item
  182. ZAP-70 1 item
  183. Angiotensin AT1 Receptors 2item
  184. Protein Arginine Methyltransferases 1 item
  185. Na /Ca2 Exchangers (NCXs) 1 item
  186. Ubiquitin-activating Enzyme E1 1 item
  187. BACE 1 item
  188. Glucagon Receptors 1 item
  189. PP4 1 item
  190. c-RET 1 item
  191. Nonstructural protein 5B (NS5B) 1 item
  192. guanylyl cyclase 1 item
  193. ETA Receptors 2item
  194. ETB Receptors 1 item
  195. p70 rsk 3item
  196. voltage-gated chloride channels 1 item
  197. 5-HT1 Receptor 1 item
  198. VEGFR3/FLT4 1 item
  199. NTRK1/TRKA 1 item
  200. CSF-1R/c-Fms 1 item
  201. Tryptophan hydroxylases (TPH) 1 item
  202. NMPRTase 1 item
  203. Bfl-1 1 item
  204. KDR 1 item
  205. Fyn kinase 1 item
  206. p53 4item
  207. metalloprotease 1 item
  208. Antifungal 1 item
  209. 5-HT receptors 1 item
  210. sodium channel 1 item
  211. c-Fms tyrosine kinase 1 item
  212. Smoothened receptor 1 item
  213. PPAR 1 item
  214. IKK 1 item
  215. Ftase 1 item
  216. Elastases 1 item
  217. ATP synthase 1 item
  218. Glucosidases 1 item
  219. Vitamin D receptors (VDRs) 1 item
  220. Antibiotic 4item
  221. Mer tyrosine kinase 1 item
  222. Hec1 1 item
  223. Stem Cell Differentiation 1 item
  224. PP2A/Nkd interaction 1 item
  225. HMGCR 1 item
  226. HIV 1 item
  227. TRPA 1 item
  228. PDK-1 1 item
  229. Prk 1 item
  230. Trx 1 item
  231. Neurokinin receptor 1 item
  232. HSP70 1 item
  233. ICAM 1 item
  234. ITK 1 item
  235. troponin 1 item
  236. Rho 1 item
  237. Aryl hydrocarbon receptors (AHRs) 1 item
  238. Ubiquitin E3 Ligases 1 item
  239. DCLK2 1 item
  240. integrase 1 item
  241. NOS 1 item
  242. GPR3 1 item
  243. Adenosine Deaminases 1 item
  244. mitochondrial pyruvate carrier (MPC) 1 item
  245. DNA gyrase 1 item
  246. Thrombin Receptor 1 item
  247. prolactin secretion 1 item
  248. gonadotropin release 1 item
  249. DprE 1 item
  250. Vitamin D 1 item
  251. Flk1 1 item
  252. SAPK 1 item
  253. p21 1 item
  254. Prostaglandin synthesis 1 item
  255. glutamate release 1 item
  256. Aromatases 1 item
  257. 5-HT 1 item
  258. TRPC channel 1 item
  259. PKD 1 item
  260. FKBP 1 item
  261. MCL1 1 item
  262. Bcl-w 1 item
  263. ACE 1 item
  264. MST 1 item
  265. PPK 1 item
  266. c-Syk 1 item
  267. CDK1/CyclinB 1 item
  268. IDO 1 item
  269. Tph 1 item
  270. reverse transcriptase 1 item
  271. Cholesterol absorption 1 item
  272. Substance P/NK1 Receptor 1 item
  273. gp120/CD4 1 item
  274. ATM 1 item
  275. PTEN 1 item
  276. NS3/4a Proteases 1 item
  277. p90 S6K 1 item
  278. Dynamins 1 item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acute Disseminated Candidiasis 1 item
  3. Acute Kidney Injury 1 item
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  6. Acute Myeloid Leukemia 9item
  7. Adrenocortical Carcinoma 1 item
  8. Advanced Renal Cell Carcinoma 1 item
  9. Autoimmune Diseases 1 item
  10. Biliary Cancer 1 item
  11. Bladder Cancer 3item
  12. Bladder Carcinoma 1 item
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  14. Brain Injuries Studies 1 item
  15. Breast Cancer 57item
  16. Cancer 253item
  17. Candida Peritonitis 1 item
  18. Candidemia 1 item
  19. Cervical Cancer 4item
  20. Cholangiocarcinoma 1 item
  21. Chronic Lymphocytic Leukemia 3item
  22. Clear Cell Renal Cell Carcinoma 1 item
  23. Colon Cancer 21item
  24. Colon Carcinoma 5item
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  26. Diabetes 1 item
  27. Epilepsy 3item
  28. Friedreich's Ataxia 1 item
  29. Fungal Infection 1 item
  30. Glioblastoma 17item
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  32. HCV 1 item
  33. Heart Failure 4item
  34. Hepatic Cancer 1 item
  35. Hepatitis C 2item
  36. Hepatocellular Carcinoma 3item
  37. HIV 7item
  38. HIV Infections 4item
  39. Hypercholesterolemia 2item
  40. Inflammatory Diseases 11item
  41. Kidney Injury Studies 1 item
  42. Leukemia 14item
  43. Liver Cancer 1 item
  44. Lung Cancer 19item
  45. Lung Carcinoma 2item
  46. Lymphoma 14item
  47. Medulloblastoma 1 item
  48. Melanoma 19item
  49. Mixed Lineage Leukemia 1 item
  50. Multiple Myeloma 6item
  51. Myelofibrosis 1 item
  52. Myeloma 3item
  53. Neuroblastoma 4item
  54. Non-small Cell Lung Cancer 15item
  55. Non-small Cell Lung Carcinoma 1 item
  56. Osteoporosis 1 item
  57. Ovarian Cancer 18item
  58. Pancreatic Cancer 26item
  59. Pancreatic Carcinoma 3item
  60. Pentacyclic Triterpenoid 1 item
  61. Prostate Cancer 30item
  62. Psoriasis 1 item
  63. Pulmonary Arterial Hypertension 1 item
  64. Pulmonary Fibrosis 1 item
  65. Renal Cancer 3item
  66. Renal Cell Carcinoma 5item
  67. Rheumatoid Arthritis 6item
  68. Schizophrenia 1 item
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  70. Squamous Cell Carcinoma 1 item
  71. Testicular Cancer 1 item
  72. Thyroid Cancer 4item
  73. Tuberculosis 4item
  74. Type 2 Diabetes 10item