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  • Search results for: 'research area pi3k akt signaling pdk 1'

Search results for: 'research area pi3k akt signaling pdk 1'

Items 181-190 of 270

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  1. Q-VD-OPh
    A1901 Q-VD-OPh
     53 Citation
    Target: Caspases
    Summary: Cell-permeable, irreversible pan-caspase inhibitor
      ≥25.67 mg/mL
  2. Dovitinib (TKI-258, CHIR-258)
    A2168 Dovitinib (TKI-258, CHIR-258)
     2 Citation
    Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Multitargeted RTK inhibitor
      insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
  3. Marimastat
    A4049 Marimastat
     1 Citation
    Target: MMP
    Summary: MMPs inhibitor,board spectrum
      ≥2.8 mg/mL
  4. UMI-77
    B4881 UMI-77
     1 Citation
    Target: Mcl-1
    Summary: Mcl-1 inhibitor, novel
      ≥23.4 mg/mL
  5. GDC-0449 (Vismodegib)
    A3021 GDC-0449 (Vismodegib)
     1 Citation
    Target: P-glycoprotein (P-gp)|Hedgehog
    Summary: Hedgehog antagonist,potent and selective
      ≥21.08 mg/mL
  6. NU7441 (KU-57788)
    A8315 NU7441 (KU-57788)
     4 Citation
    Target: PI3K|DNA-PK
    Summary: DNA-PK inhibitor
      insoluble in EtOH; insoluble in H2O; ≥4.13 mg/mL
  7. Obatoclax mesylate (GX15-070)
    A4194 Obatoclax mesylate (GX15-070)
     1 Citation
    Target: Bcl-2
    Summary: Potent Bcl-2 inhibitor
      insoluble in H2O; ≥20.7 mg/mL
  8. KU-0060648
    A1769 KU-0060648
     1 Citation
    Target: PI3K|DNA-PK
    Summary: Dual DNA-PK/PI3-K inhibitor, ATP-competitive
  9. CYC116
    A4125 CYC116
    Target: Aurora Kinases|FLT3|VEGFR
    Summary: Potent Aurora A/B inhibitor
      insoluble in EtOH; insoluble in H2O; ≥18.4 mg/mL
  10. GDC-0032
    B1047 GDC-0032
    Target: PI3K
    Summary: PI3Kα inhibitor
      ≥23.05 mg/mL

Items 181-190 of 270

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Category
  1. Signaling Pathways 265item
  2. Natural Products 4item
  3. Probes & Dyes 1 item
  4. Lab Reagents 1 item
Specificity
  1. Selective 216item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 13item
  2. Irreversible 5item
Target
  1. Caspases 2item
  2. Cyclin-Dependent Kinases 12item
  3. Proteasome 1 item
  4. Histone Deacetylases (HDACs) 8item
  5. Akt 10item
  6. Bcl-2 7item
  7. PI3K 23item
  8. CXCR 1 item
  9. Raf 9item
  10. Aurora Kinases 5item
  11. Bcl-xl 2item
  12. CSF-1R 1 item
  13. MDM2 1 item
  14. EZH2 3item
  15. mTOR 13item
  16. Bromodomains 1 item
  17. AP-1 1 item
  18. MMP 3item
  19. Androgen Receptors 3item
  20. FLT3 6item
  21. GSK-3 4item
  22. LPA Receptors 1 item
  23. P-glycoprotein (P-gp) 1 item
  24. PLK 6item
  25. Chk 2item
  26. VEGFR 22item
  27. PDGFR 11item
  28. c-Kit 4item
  29. RET 3item
  30. Bromodomain-containing proteins(BRDs) 1 item
  31. Phosphodiesterases (PDEs) 1 item
  32. Mcl-1 5item
  33. p38 2item
  34. JNK 1 item
  35. SGK 2item
  36. Bcr-Abl 3item
  37. MEK 8item
  38. PORCN 1 item
  39. DOT1L 1 item
  40. FGFR 3item
  41. Insulin-like growth factor receptors(IGFRs) 1 item
  42. Pim 1 item
  43. Liver X receptors (LXRs) 1 item
  44. Sir2-like Family Deacetylases (Sirtuins) 2item
  45. Deubiquitinating enzymes (DUBs) 2item
  46. PP1 1 item
  47. PP2A 1 item
  48. Smoothened 2item
  49. MET 1 item
  50. Src 5item
  51. Trk Receptors 2item
  52. Aminopeptidases 1 item
  53. STAT 7item
  54. Microtubules/Tubulins 5item
  55. Estrogen and Related Receptors 1 item
  56. EGFR 4item
  57. Hedgehog 1 item
  58. PAK 1 item
  59. Hypoxia Inducible Factors (HIFs) 1 item
  60. BMP and Other Activin Receptors 1 item
  61. JAK 5item
  62. p300 1 item
  63. Syk 1 item
  64. EZH1 1 item
  65. DNA-PK 4item
  66. HSP90 2item
  67. Gutathione S-transferase 1 item
  68. CCR 1 item
  69. eIF4E/eIF3G interaction 1 item
  70. TNKS 1 item
  71. Topoisomerases 3item
  72. Cytochrome P450 (CYP450) 2item
  73. Actin 1 item
  74. ERK 3item
  75. Vacuolar-type ATPase 1 item
  76. c-MET 3item
  77. BMI-1 1 item
  78. PKC 6item
  79. Calpains 1 item
  80. RAD51 1 item
  81. 5-HT2 Receptors 2item
  82. Calcium chelator 1 item
  83. PARP 3item
  84. ALK 1 item
  85. Sphingosine kinases (SphKs) 2item
  86. Monocarboxylate transporters (MCTs) 1 item
  87. PKG 1 item
  88. PKA 4item
  89. GPR30 1 item
  90. D2 Receptors 1 item
  91. MK2 1 item
  92. Tie-2 1 item
  93. RSK 1 item
  94. Autophagy 3item
  95. ATM/ATR 2item
  96. COX 2item
  97. YAP 1 item
  98. CK1 1 item
  99. CK2 1 item
  100. Pregnane X Receptors 1 item
  101. G-quadruplexes 1 item
  102. Nampt 1 item
  103. P2X Receptors 1 item
  104. Glutaminases 1 item
  105. Carbonic Anhydrases 1 item
  106. Ron 1 item
  107. BLM 1 item
  108. Synthases/Synthetases 1 item
  109. MAGL 1 item
  110. Inositol-requiring enzyme 1 (IRE1) 1 item
  111. RNA Polymerases 1 item
  112. DYRK 1 item
  113. Norepinephrine transporter 1 item
  114. 5-HT Transporters 1 item
  115. Guanylyl Cyclases 1 item
  116. Histone Demethylases 1 item
  117. MNK 1 item
  118. HIV-1 reverse transcriptase 1 item
  119. Insulin Receptors 1 item
  120. IRG-1R 1 item
  121. eEF-2 1 item
  122. ZAP-70 1 item
  123. Protein Arginine Methyltransferases 1 item
  124. BACE 1 item
  125. PP4 1 item
  126. p70 rsk 2item
  127. VEGFR3/FLT4 1 item
  128. NTRK1/TRKA 1 item
  129. CSF-1R/c-Fms 1 item
  130. NMPRTase 1 item
  131. Bfl-1 1 item
  132. KDR 1 item
  133. p53 2item
  134. Smoothened receptor 1 item
  135. Antibiotic 1 item
  136. Hec1 1 item
  137. PDK-1 1 item
  138. Prk 1 item
  139. Trx 1 item
  140. HSP70 1 item
  141. Adenosine Deaminases 1 item
  142. Flk1 1 item
  143. MCL1 1 item
  144. Bcl-w 1 item
  145. PPK 1 item
  146. c-Syk 1 item
  147. CDK1/CyclinB 1 item
  148. Substance P/NK1 Receptor 1 item
Reported Experiments
  1. Animal Experiments 253item
  2. Cell Experiments 171item