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Search results for: 'research area pi3k akt signaling pdk 1'

Items 471-480 of 2414

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  1. HA-100 (hydrochloride)
    C4953 HA-100 (hydrochloride)
    Summary: inhibitor of protein kinases (PKs)
      insoluble in EtOH; ≥131.8 mg/mL
  2. PLX-4720
    A3016 PLX-4720
     1 Citation
    Target: Raf
    Summary: BRAF kinase inhibitor
      ≥20.69 mg/mL
  3. LDN193189 Hydrochloride
    A3545 LDN193189 Hydrochloride
     1 Citation
    Summary: ALK inhibitor,potent and selective
      ≥27.6 mg/mL
  4. SB-505124 hydrochloride
    A3799 SB-505124 hydrochloride
    Target: ALK
    Summary: ALK5/ALK4/ALK7 inhibitor in TGF-β/activin signalling,selective
  5. AZD6244 (Selumetinib)
    A8207 AZD6244 (Selumetinib)
     3 Citation
    Summary: MEK inhibitor
      ≥22.88 mg/mL
  6. GDC-0879
    A5071 GDC-0879
     1 Citation
    Target: Raf
    Summary: B-Raf inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥16.7 mg/mL
  7. PD184352 (CI-1040)
    A1792 PD184352 (CI-1040)
    Target: MEK
    Summary: Selective MEK inhibitor
      ≥47.9 mg/mL
  8. SB202190 (FHPI)
    A1632 SB202190 (FHPI)
     5 Citation
    Target: p38
    Summary: P38 MAPK inhibitor
  9. CEP-32496
    A1413 CEP-32496
    Summary: BRAF(V600E)inhibitor,highly potent
      ≥25.85 mg/mL
  10. PH-797804
    A8308 PH-797804
     1 Citation
    Summary: P38 MAP kinase inhibitor, potent and selective
      ≥23.85 mg/mL

Items 471-480 of 2414

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  7. Protein 13item
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Specificity
  1. Selective 404item
  2. Non-Selective 2item
Reversibility
  1. Reversible 23item
  2. Irreversible 9item
Target
  1. Caspases 7item
  2. Cyclin-Dependent Kinases 16item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 2item
  5. Cathepsins 3item
  6. Histone Deacetylases (HDACs) 12item
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  8. Akt 12item
  9. Bcl-2 8item
  10. PI3K 33item
  11. CXCR 1 item
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  24. Acyl coenzyme A: cholesterol acyltransferases 1 item
  25. FLT3 11item
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  27. Factor Xa 1 item
  28. LPA Receptors 3item
  29. P-glycoprotein (P-gp) 1 item
  30. PLK 6item
  31. Chk 4item
  32. VEGFR 24item
  33. PDGFR 14item
  34. c-Kit 6item
  35. RET 3item
  36. IRAK 3item
  37. Bromodomain-containing proteins(BRDs) 1 item
  38. Phosphodiesterases (PDEs) 2item
  39. Mcl-1 7item
  40. p38 6item
  41. PKB 1 item
  42. JNK 5item
  43. SGK 2item
  44. Bcr-Abl 7item
  45. MEK 11item
  46. PORCN 1 item
  47. DOT1L 1 item
  48. FGFR 4item
  49. Insulin-like growth factor receptors(IGFRs) 1 item
  50. CGRP receptors 1 item
  51. Pim 2item
  52. GABAB Receptors 1 item
  53. Liver X receptors (LXRs) 1 item
  54. Glucagon-like peptide 1 (GLP-1) receptors 2item
  55. Sir2-like Family Deacetylases (Sirtuins) 3item
  56. Voltage-gated Sodium (NaV) Channels 1 item
  57. Deubiquitinating enzymes (DUBs) 2item
  58. PP1 1 item
  59. PP2A 1 item
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  65. Aminopeptidases 3item
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  69. Estrogen and Related Receptors 2item
  70. EGFR 5item
  71. Hedgehog 1 item
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  74. BTK 1 item
  75. RIP kinases 1 item
  76. Monocyte chemotactic proteins 1 item
  77. PAK 1 item
  78. PD-1/PD-L1 interaction 1 item
  79. Hypoxia Inducible Factors (HIFs) 1 item
  80. BMP and Other Activin Receptors 2item
  81. JAK 10item
  82. p300 1 item
  83. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  84. Syk 3item
  85. Progesterone Receptors 1 item
  86. EZH1 1 item
  87. DNA-PK 6item
  88. HSP90 2item
  89. AMPK 1 item
  90. Gutathione S-transferase 1 item
  91. CCR 2item
  92. Angiotensin AT2 Receptors 1 item
  93. eIF4E/eIF3G interaction 1 item
  94. TNKS 1 item
  95. Topoisomerases 6item
  96. Cytochrome P450 (CYP450) 4item
  97. Ferroptosis 1 item
  98. Toll-like receptors (TLRs) 3item
  99. Actin 2item
  100. DNA Methyltransferases 2item
  101. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  102. ERK 6item
  103. HMG-CoA Reductases 1 item
  104. Vacuolar-type ATPase 1 item
  105. c-MET 3item
  106. BMI-1 1 item
  107. PKC 8item
  108. Calpains 2item
  109. M1 Receptors 1 item
  110. HCV Proteases 1 item
  111. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  112. O-GlcNAcase 1 item
  113. Protease-Activated Receptors 2item
  114. RAD51 1 item
  115. USP 1 item
  116. 5-HT2 Receptors 3item
  117. LRRK2 2item
  118. Calcium chelator 1 item
  119. DGAT 2item
  120. Insulin and Insulin-like Receptors 2item
  121. PARP 6item
  122. CB1 Receptors 2item
  123. Melanocortin (MC) Receptors 1 item
  124. ALK 2item
  125. Sphingosine kinases (SphKs) 2item
  126. Trypsin 1 item
  127. Chymotrypsin 1 item
  128. Kallikrein 1 item
  129. Trypsinogen 1 item
  130. Monocarboxylate transporters (MCTs) 2item
  131. PKG 1 item
  132. PKA 5item
  133. GPR30 1 item
  134. HIV-1 gp120 1 item
  135. D2 Receptors 1 item
  136. TBK1 1 item
  137. MARK1 1 item
  138. NUAK1 1 item
  139. Lactate Dehydrogenases (LDH) 1 item
  140. MK2 2item
  141. Fatty-acid-binding proteins (FABPs) 1 item
  142. Tie-2 2item
  143. RSK 1 item
  144. Free Fatty Acid Receptors 1 item
  145. phosphatases 1 item
  146. Autophagy 3item
  147. ATM/ATR 3item
  148. COX 7item
  149. YAP 1 item
  150. CK1 2item
  151. CK2 1 item
  152. HIV Integrases 1 item
  153. Pregnane X Receptors 1 item
  154. Cryptochromes 1 item
  155. G-quadruplexes 1 item
  156. NAT10 1 item
  157. Nampt 1 item
  158. P2X Receptors 1 item
  159. Glutaminases 1 item
  160. Carbonic Anhydrases 2item
  161. Ron 1 item
  162. BLM 1 item
  163. HSV 2item
  164. NADPH Oxidases 1 item
  165. Calcium-activated chloride channels (CaCC) 1 item
  166. GPR35 1 item
  167. Aldehyde Dehydrogenases 1 item
  168. Synthases/Synthetases 1 item
  169. MAGL 1 item
  170. c-Fyn 1 item
  171. Leukotriene and Related Receptors 1 item
  172. Histamine H1 Receptors 3item
  173. RAR/RXR 1 item
  174. Na /K ATPases 1 item
  175. Inositol-requiring enzyme 1 (IRE1) 1 item
  176. SETD7 1 item
  177. Na /K /Cl- Symporters (NKCCs) 1 item
  178. Organic anion transporters (OATs) 1 item
  179. TRP Channel 3item
  180. RNA Polymerases 2item
  181. DYRK 1 item
  182. Norepinephrine transporter 1 item
  183. 5-HT Transporters 1 item
  184. Guanylyl Cyclases 1 item
  185. Histone Demethylases 1 item
  186. MNK 2item
  187. NO Donors / Precursors 1 item
  188. CB2 Receptors 1 item
  189. HIV-1 reverse transcriptase 1 item
  190. IL Receptors 1 item
  191. Para-aminobenzoic acid 1 item
  192. 15-lipoxygenases 1 item
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  195. IRG-1R 1 item
  196. eEF-2 1 item
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  199. Nuclear Receptors 1 item
  200. ZAP-70 1 item
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  202. Protein Arginine Methyltransferases 1 item
  203. Na /Ca2 Exchangers (NCXs) 1 item
  204. Ubiquitin-activating Enzyme E1 1 item
  205. BACE 1 item
  206. Glucagon Receptors 1 item
  207. PP4 1 item
  208. c-RET 1 item
  209. Nonstructural protein 5B (NS5B) 1 item
  210. guanylyl cyclase 1 item
  211. ETA Receptors 2item
  212. ETB Receptors 1 item
  213. p70 rsk 3item
  214. voltage-gated chloride channels 1 item
  215. 5-HT1 Receptor 1 item
  216. VEGFR3/FLT4 1 item
  217. NTRK1/TRKA 1 item
  218. CSF-1R/c-Fms 1 item
  219. Menin-MLL 2item
  220. Tryptophan hydroxylases (TPH) 1 item
  221. NMPRTase 1 item
  222. Bfl-1 1 item
  223. sodium channels 1 item
  224. KDR 1 item
  225. Fyn kinase 1 item
  226. dCTP Pyrophosphatases 1 item
  227. Protein polybromo-1 1 item
  228. SMARCA4 1 item
  229. SMARCA2 1 item
  230. p53 4item
  231. metalloprotease 1 item
  232. Antifungal 1 item
  233. 5-HT receptors 1 item
  234. sodium channel 1 item
  235. c-Fms tyrosine kinase 1 item
  236. PAR 1 item
  237. Smoothened receptor 1 item
  238. Nrf2/ARE signal 1 item
  239. PPAR 2item
  240. USP1/USF1 complex 1 item
  241. IKK 1 item
  242. TRPV 1 item
  243. Ftase 1 item
  244. Elastases 1 item
  245. ATP synthase 1 item
  246. Glucosidases 1 item
  247. Vitamin D receptors (VDRs) 1 item
  248. Antibiotic 4item
  249. Mer tyrosine kinase 1 item
  250. Hec1 1 item
  251. Stem Cell Differentiation 1 item
  252. PP2A/Nkd interaction 1 item
  253. HMGCR 1 item
  254. HIV 1 item
  255. TRPA 1 item
  256. PDK-1 1 item
  257. telomerase 1 item
  258. Prk 1 item
  259. Trx 1 item
  260. Neurokinin receptor 1 item
  261. HSP70 1 item
  262. ICAM 1 item
  263. ITK 1 item
  264. NOD1 1 item
  265. troponin 1 item
  266. Rho 1 item
  267. Aryl hydrocarbon receptors (AHRs) 1 item
  268. Ubiquitin E3 Ligases 1 item
  269. DCLK2 1 item
  270. integrase 1 item
  271. L3MBTL 1 item
  272. NOS 1 item
  273. GPR3 1 item
  274. Lck 1 item
  275. Adenosine Deaminases 1 item
  276. mitochondrial pyruvate carrier (MPC) 1 item
  277. DNA gyrase 1 item
  278. Thrombin Receptor 1 item
  279. prolactin secretion 1 item
  280. gonadotropin release 1 item
  281. DprE 1 item
  282. Vitamin D 1 item
  283. Flk1 1 item
  284. SAPK 1 item
  285. p21 1 item
  286. Prostaglandin synthesis 1 item
  287. glutamate release 1 item
  288. Aromatases 1 item
  289. 5-HT 1 item
  290. TRPC channel 1 item
  291. PKD 1 item
  292. Octamer-binding transcription factor 4 (Oct4) 1 item
  293. FKBP 1 item
  294. MCL1 1 item
  295. Bcl-w 1 item
  296. ACE 1 item
  297. MST 1 item
  298. PPK 1 item
  299. c-Syk 1 item
  300. CDK1/CyclinB 1 item
  301. IDO 1 item
  302. Tph 1 item
  303. reverse transcriptase 1 item
  304. Cholesterol absorption 1 item
  305. Substance P/NK1 Receptor 1 item
  306. gp120/CD4 1 item
  307. ATM 2item
  308. PTEN 1 item
  309. NS3/4a Proteases 1 item
  310. p90 S6K 1 item
  311. Dynamins 1 item
Reported Experiments
  1. Animal Experiments 509item
  2. Cell Experiments 412item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acute Disseminated Candidiasis 1 item
  3. Acute Kidney Injury 1 item
  4. Acute Lung Injury 1 item
  5. Acute Myelogenous Leukemia 1 item
  6. Acute Myeloid Leukemia 10item
  7. Adrenocortical Carcinoma 1 item
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  16. Cancer 270item
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  26. Diabetes 3item
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  28. Friedreich's Ataxia 1 item
  29. Fungal Infection 1 item
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  34. Hepatic Cancer 1 item
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  37. HIV 8item
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  40. Inflammatory Diseases 11item
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  43. Liver Cancer 1 item
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  45. Lung Carcinoma 2item
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  47. Medulloblastoma 1 item
  48. Melanoma 19item
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  50. Multiple Myeloma 7item
  51. Myelofibrosis 1 item
  52. Myeloma 3item
  53. Neuroblastoma 4item
  54. Non-small Cell Lung Cancer 15item
  55. Non-small Cell Lung Carcinoma 1 item
  56. Osteoporosis 1 item
  57. Ovarian Cancer 18item
  58. Pancreatic Cancer 27item
  59. Pancreatic Carcinoma 3item
  60. Pentacyclic Triterpenoid 1 item
  61. Prostate Cancer 34item
  62. Psoriasis 1 item
  63. Pulmonary Arterial Hypertension 1 item
  64. Pulmonary Fibrosis 1 item
  65. Renal Cancer 3item
  66. Renal Cell Carcinoma 5item
  67. Rheumatoid Arthritis 6item
  68. Schizophrenia 1 item
  69. Sleep Disorders 1 item
  70. Squamous Cell Carcinoma 1 item
  71. Testicular Cancer 1 item
  72. Thyroid Cancer 4item
  73. Tuberculosis 4item
  74. Type 2 Diabetes 11item