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Search results for: 'research area pi3k akt signaling pdk 1'

Search results for: 'research area pi3k akt signaling pdk 1'

A8346 BYL-719

1 Citation

Target: PI3K

Summary: Selective PI3Kα inhibitor

≥22.07 mg/mL
A5566 LY2228820

1 Citation

Target: p38

Summary: P38 MAP kinase inhibitor

≥30.65 mg/mL
A1632 SB202190 (FHPI)

5 Citation

Target: p38

Summary: P38 MAPK inhibitor
A3018 Trametinib (GSK1120212)

7 Citation

Target: MEK

Summary: MEK1 and MEK2 inhibitor, potent and selective

insoluble in H2O; insoluble in EtOH; ≥15.38 mg/mL
A8446 Ibuprofen

Target: COX

Summary: inhibitor of cyclooxygenase 1 and cyclooxygenase 2

insoluble in H2O; ≥10.31 mg/mL
A8236 Regorafenib

4 Citation

Target: Raf|VEGFR|PDGFR|c-Kit|RET

Summary: Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1

≥25.04 mg/mL
A3433 Gefitinib hydrochloride

Target: EGFR

Summary: Potent EGFR inhibitor

insoluble in EtOH; ≥4.28 mg/mL
A8681 Ro3280

Target: PLK

Summary: PLK1 inhibitor,potent and highly selective

≥27.2 mg/mL
A8252 Nintedanib (BIBF 1120)

3 Citation

Target: VEGFR|PDGFR|FGFR

Summary: VEGFR/PDGFR/FGFR inhibitor

insoluble in H2O; insoluble in EtOH; ≥5.34 mg/mL
B2293 Irinotecan HCl Trihydrate

Target: Topoisomerases

Summary: Topoisomerase 1 inhibitor

≥23.1 mg/mL