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Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Items 41-50 of 750

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  1. Pyroxamide
    A4497 Pyroxamide
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC1 inhibitor
      Soluble in DMSO
  2. SBHA
    A4498 SBHA
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC1/HDAC3 inhibitor,cell-permeable
      insoluble in EtOH; ≥9 mg/mL
  3. NSC 3852
    A4496 NSC 3852
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor
      insoluble in EtOH; insoluble in H2O; ≥7.35 mg/mL
  4. GM 6001
    A4050 GM 6001
     2 Citation
    Target: MMP
    Summary: Broad spectrum MMP inhibitor
      insoluble in H2O; insoluble in EtOH; ≥19.42 mg/mL
  5. PCI-34051
    A4091 PCI-34051
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC8 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥14.8 mg/mL
  6. MC1568
    A4094 MC1568
     3 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: Class II HDAC inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥15.7 mg/mL
  7. ITF2357 (Givinostat)
    A4093 ITF2357 (Givinostat)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor
      ≥23.8 mg/mL
  8. Doxycycline hyclate
    A4052 Doxycycline hyclate
    Target: MMP
    Summary: MMP inhibitor
      ≥22.15 mg/mL
  9. Sodium Phenylbutyrate
    A4107 Sodium Phenylbutyrate
    Target: Histone Deacetylases (HDACs)
    Summary: Histone deacetylase inhibitor
      ≥27.65 mg/mL
  10. PD153035 hydrochloride
    A8199 PD153035 hydrochloride
     1 Citation
    Target: EGFR
    Summary: Potent EGFR inhibitor
      insoluble in EtOH; insoluble in H2O; ≥3.97 mg/mL

Items 41-50 of 750

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Category
  1. Proteases 68item
  2. Apoptosis 47item
  3. Chromatin/Epigenetics 96item
  4. Metabolism 74item
  5. MAPK Signaling 31item
  6. Tyrosine Kinase 97item
  7. DNA Damage/DNA Repair 60item
  8. PI3K/Akt/mTOR Signaling 61item
  9. Microbiology & Virology 31item
  10. Cell Cycle/Checkpoint 68item
  11. Ubiquitination/ Proteasome 27item
  12. JAK/STAT Signaling 36item
  13. TGF-β / Smad Signaling 30item
  14. Angiogenesis 5item
  15. GPCR/G protein 16item
  16. Stem Cell 24item
  17. Membrane Transporter/Ion Channel 26item
  18. Cancer Biology 3item
  19. Endocrinology and Hormones 12item
  20. Neuroscience 36item
  21. Obesity, Appetite Control & Diabetes 1 item
  22. Other Signal Transduction 7item
  23. Others 58item
  24. Immunology/Inflammation 14item
  25. Cardiovascular 5item
Specificity
  1. Selective 455item
  2. Non-Selective 3item
Reversibility
  1. Reversible 34item
  2. Irreversible 25item
Target
  1. Caspases 6item
  2. Cyclin-Dependent Kinases 21item
  3. Proteasome 11item
  4. Cathepsins 5item
  5. Histone Deacetylases (HDACs) 25item
  6. Akt 11item
  7. Bcl-2 8item
  8. PI3K 28item
  9. CXCR 2item
  10. Raf 10item
  11. Aurora Kinases 18item
  12. Bcl-xl 3item
  13. CSF-1R 4item
  14. Glycoproteins 1 item
  15. p97 1 item
  16. Gap Junctions 1 item
  17. MDM2 1 item
  18. EZH2 3item
  19. mTOR 16item
  20. Bromodomains 5item
  21. AP-1 1 item
  22. MMP 6item
  23. Thymidine Phosphorylases 1 item
  24. Androgen Receptors 3item
  25. Peptidylprolyl isomerases 1 item
  26. Acyl coenzyme A: cholesterol acyltransferases 1 item
  27. Myosin II ATPases 1 item
  28. DT-diaphorases 1 item
  29. Voltage-gated Potassium (KV) Channels 1 item
  30. MER 1 item
  31. FLT3 16item
  32. GSK-3 6item
  33. Factor Xa 4item
  34. P-glycoprotein (P-gp) 3item
  35. PLK 9item
  36. Chk 4item
  37. Eph Receptors 2item
  38. VEGFR 28item
  39. PDGFR 19item
  40. c-Kit 9item
  41. RET 2item
  42. IRAK 2item
  43. Bromodomain-containing proteins(BRDs) 1 item
  44. Phosphodiesterases (PDEs) 12item
  45. Mcl-1 5item
  46. Hydrolase 1 item
  47. Thymidylate Synthase 3item
  48. p38 6item
  49. PKB 1 item
  50. JNK 1 item
  51. Bcr-Abl 10item
  52. MEK 8item
  53. PORCN 1 item
  54. DOT1L 1 item
  55. FGFR 10item
  56. Nrf2 1 item
  57. Pim 3item
  58. GABAB Receptors 1 item
  59. Sir2-like Family Deacetylases (Sirtuins) 1 item
  60. Voltage-gated Sodium (NaV) Channels 1 item
  61. Deubiquitinating enzymes (DUBs) 2item
  62. Smoothened 1 item
  63. Neuraminidases (NA) 1 item
  64. MET 5item
  65. Src 14item
  66. Trk Receptors 4item
  67. Aminopeptidases 1 item
  68. NMDA Receptors 1 item
  69. STAT 6item
  70. Microtubules/Tubulins 1 item
  71. EGFR 18item
  72. Reverse Transcriptases 5item
  73. ROCK 7item
  74. Hypoxia Inducible Factors (HIFs) 1 item
  75. FAK 3item
  76. JAK 17item
  77. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  78. Syk 4item
  79. EZH1 1 item
  80. DNA-PK 6item
  81. HSP90 8item
  82. AMPK 1 item
  83. CFTR 2item
  84. Topoisomerases 10item
  85. Cytochrome P450 (CYP450) 7item
  86. Ksp 1 item
  87. Renin 1 item
  88. ErbB 4item
  89. Toll-like receptors (TLRs) 2item
  90. Actin 2item
  91. Serine Proteases 1 item
  92. DNA Methyltransferases 1 item
  93. ERK 6item
  94. HMG-CoA Reductases 4item
  95. c-MET 6item
  96. PKC 11item
  97. Calpains 3item
  98. Ca2 /calmodulin-dependent protein kinases (CaMKs) 4item
  99. Protease-Activated Receptors 1 item
  100. Lyn 1 item
  101. RAD51 1 item
  102. HER2 1 item
  103. Pyk2 2item
  104. 5-HT2 Receptors 3item
  105. LRRK2 5item
  106. Voltage-gated Calcium Channels (CaV) 1 item
  107. DGAT 1 item
  108. Insulin and Insulin-like Receptors 4item
  109. PARP 6item
  110. Pyruvate dehydrogenases (PDH) 1 item
  111. ALK 6item
  112. Sphingosine kinases (SphKs) 2item
  113. Monocarboxylate transporters (MCTs) 1 item
  114. CETP 1 item
  115. PKG 2item
  116. PKA 5item
  117. Myosin light chain kinases (MLCKs) 2item
  118. D1 and D5 Receptors 1 item
  119. D2 Receptors 3item
  120. D3 Receptors 2item
  121. 5-HT1 Receptors 2item
  122. 5-HT7 Receptors 1 item
  123. Lactate Dehydrogenases (LDH) 2item
  124. MK2 2item
  125. Angiotensin-Converting Enzymes (ACEs) 3item
  126. Tie-2 3item
  127. RSK 2item
  128. phosphatases 1 item
  129. Autophagy 3item
  130. ATM/ATR 5item
  131. COX 10item
  132. CK1 1 item
  133. CK2 3item
  134. HIPK2 1 item
  135. HIPK3 1 item
  136. HIV Integrases 1 item
  137. Squalene epoxidases 1 item
  138. PRAK 1 item
  139. MAPKAP-K2 1 item
  140. 20S proteasomal chymotrypsin 1 item
  141. Geranylgeranyltransferase I 1 item
  142. Farnesyltransferase 1 item
  143. Nampt 3item
  144. eIF4F 1 item
  145. Cdc42 1 item
  146. SRPK1 1 item
  147. P2X Receptors 1 item
  148. Glutaminases 2item
  149. Carbonic Anhydrases 6item
  150. Ron 1 item
  151. G9a 1 item
  152. BLM 1 item
  153. HSV 1 item
  154. NADPH Oxidases 3item
  155. Calcium-activated chloride channels (CaCC) 1 item
  156. GPR35 1 item
  157. Aldehyde Dehydrogenases 1 item
  158. Synthases/Synthetases 2item
  159. Histamine H1 Receptors 3item
  160. Na /K ATPases 2item
  161. P110 1 item
  162. Hck 2item
  163. Inositol-requiring enzyme 1 (IRE1) 1 item
  164. Na /K /Cl- Symporters (NKCCs) 2item
  165. GABAA Receptors 1 item
  166. Phospholipases 1 item
  167. RNA Polymerases 1 item
  168. DYRK 1 item
  169. Norepinephrine transporter 1 item
  170. 5-HT Transporters 3item
  171. Xanthine oxidoreductases 1 item
  172. Dihydroorotate dehydrogenase 1 item
  173. MNK 2item
  174. 5-Lipoxygenases 1 item
  175. NO Donors / Precursors 1 item
  176. HIV-1 reverse transcriptase 1 item
  177. IL Receptors 2item
  178. CCL2 1 item
  179. Norepinephrine transporters 1 item
  180. Calcium-Activated Potassium (KCa) Channels 2item
  181. AChE 3item
  182. Insulin Receptors 1 item
  183. IRG-1R 1 item
  184. cAMP 1 item
  185. Sulfonylurea receptors 1 item
  186. eEF-2 1 item
  187. Inward Rectifier Potassium (Kir) Channels 2item
  188. Cdc7 1 item
  189. CMV 1 item
  190. ZAP-70 1 item
  191. Catechol O-Methyltransferase (COMT) 2item
  192. fibrinolysis 1 item
  193. Angiotensin AT1 Receptors 1 item
  194. D4 Receptors 1 item
  195. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  196. NMDA receptor 1 item
  197. HBV Proteases 1 item
  198. Hydroxylases 2item
  199. Flk-1 1 item
  200. Papains 1 item
  201. Protein Arginine Methyltransferases 1 item
  202. IMPDH 1 item
  203. Na /Ca2 Exchangers (NCXs) 1 item
  204. NAE 2item
  205. Ubiquitin-activating Enzyme E1 2item
  206. SUMOylation 1 item
  207. ATGL 1 item
  208. BACE 3item
  209. Cytidine deaminases 1 item
  210. angiogenesis 1 item
  211. Glucagon Receptors 1 item
  212. 15-PGDH 1 item
  213. DPP-4 5item
  214. c-RET 3item
  215. Nonstructural protein 5B (NS5B) 1 item
  216. p70 rsk 3item
  217. voltage-gated chloride channels 1 item
  218. FPTase 1 item
  219. Microtubule/Tubulin 1 item
  220. VEGFR3/FLT4 1 item
  221. NTRK1/TRKA 1 item
  222. CSF-1R/c-Fms 1 item
  223. Menin-MLL 2item
  224. Tryptophan hydroxylases (TPH) 2item
  225. ADAMs 1 item
  226. NMPRTase 1 item
  227. Bfl-1 1 item
  228. TAM kinase 1 item
  229. sodium channels 1 item
  230. p53-MDM2 interaction 2item
  231. nuclear export 1 item
  232. CRM1 1 item
  233. PTP 1 item
  234. KDR 2item
  235. Fyn kinase 1 item
  236. Abl kinases 1 item
  237. AXL 1 item
  238. Glyoxalase I 1 item
  239. dCTP Pyrophosphatases 1 item
  240. Protein polybromo-1 1 item
  241. SMARCA4 1 item
  242. SMARCA2 1 item
  243. Dipeptidyl-peptidase II 1 item
  244. p53 4item
  245. metalloprotease 1 item
  246. HDAC 2item
  247. KDM 2item
  248. 5-HT receptors 1 item
  249. sodium channel 2item
  250. c-Fms tyrosine kinase 1 item
  251. human lyase 1 item
  252. insulin 1 item
  253. Ub-conjugating enzyme (E2) complex 1 item
  254. Smoothened receptor 1 item
  255. quinone oxidoreductase 1 item
  256. cysteine protease 2item
  257. Nrf2/ARE signal 1 item
  258. PPAR 1 item
  259. STK 1 item
  260. USP1/USF1 complex 1 item
  261. IKK 1 item
  262. MSK 1 item
  263. gp120-CD4 interaction 1 item
  264. HCV polymerase 3item
  265. Ftase 1 item
  266. Subtilisin/Kex2p-like proprotein convertase 1 item
  267. PC-PLC 2item
  268. Elastases 1 item
  269. P97 ATPase 1 item
  270. NTPDases 1 item
  271. Antibiotic 1 item
  272. Mer tyrosine kinase 1 item
  273. Hec1 1 item
  274. neprilysin 1 item
  275. GLI 1 item
  276. HMGCR 1 item
  277. AAT 1 item
  278. ErbB-2 1 item
  279. adrenergic receptor 2item
  280. 5-HT4 Receptor 1 item
  281. sterol demethylase 1 item
  282. PDK-1 1 item
  283. GAPDH 1 item
  284. telomerase 1 item
  285. Histone Acetyltransferases (HATs) 3item
  286. complex I of the mitochondrial electron transport chain 1 item
  287. F1 Fo-ATPase 1 item
  288. Prk 1 item
  289. potassium channel 1 item
  290. calcium channel 1 item
  291. Ribonucleotide Reductases 1 item
  292. Trx 1 item
  293. Tyrosinases 1 item
  294. HSP70 1 item
  295. ICAM 1 item
  296. ITK 1 item
  297. HIF-PH 1 item
  298. NOD1 1 item
  299. NUAK 1 item
  300. Rho 1 item
  301. Ubiquitin E3 Ligases 1 item
  302. DCLK2 1 item
  303. FAAH 1 item
  304. PTK 1 item
  305. integrase 1 item
  306. L3MBTL 1 item
  307. NOS 2item
  308. MDMX 1 item
  309. TYK2 2item
  310. MUSK 1 item
  311. MAP3K 1 item
  312. GPR3 1 item
  313. Lck 1 item
  314. Adenosine Deaminases 2item
  315. mitochondrial pyruvate carrier (MPC) 1 item
  316. Thrombin Receptor 1 item
  317. prolactin secretion 1 item
  318. gonadotropin release 1 item
  319. DprE 1 item
  320. carnitine reabsorption 1 item
  321. Histamine receptors 1 item
  322. GluR 1 item
  323. 5-HT receptor 1 item
  324. dopamine receptors 1 item
  325. AMPA receptor 1 item
  326. 5-alpha Reductases 1 item
  327. Flk1 2item
  328. p21 1 item
  329. DNA Ligases 1 item
  330. Prostaglandin synthesis 1 item
  331. Protein Tyrosine Phosphatases 1 item
  332. alkaline phosphatases 1 item
  333. ATPases 1 item
  334. glutamate release 1 item
  335. PAFR 1 item
  336. Aromatases 2item
  337. DHFR 1 item
  338. GARFT 1 item
  339. PHF 1 item
  340. FGR 1 item
  341. YES 2item
  342. Fyn 2item
  343. ARG 1 item
  344. Autotaxin 1 item
  345. UCH 1 item
  346. RHA 1 item
  347. HCV NS3-4A protease 1 item
  348. TRPC channel 1 item
  349. PKD 1 item
  350. Thioredoxin Reductases 1 item
  351. enoyl-acyl-carrier protein reductase 1 item
  352. SHIP 1 item
  353. FKBP 1 item
  354. MCL1 1 item
  355. Bcl-w 1 item
  356. glutathione peroxidase 4 1 item
  357. NADH oxidase 1 item
  358. S-adenosylhomocysteine hydrolase 1 item
  359. Rho-kinase 1 item
  360. tropomyosin receptor kinase 1 item
  361. LSD 1 item
  362. DDX3 1 item
  363. PRMT 1 item
  364. ACE 1 item
  365. GLP 1 item
  366. SK 1 item
  367. MST 1 item
  368. PPK 1 item
  369. c-Syk 1 item
  370. CDK1/CyclinB 1 item
  371. NHE 1 item
  372. IDO 1 item
  373. Tph 1 item
  374. PIM1 kinase 1 item
  375. phospholipase A2 1 item
  376. reverse transcriptase 1 item
  377. epoxide hydrolase 1 item
  378. Serotonin (5-HT) reuptake 1 item
  379. Cholesterol absorption 1 item
  380. Vascular Disrupting Agents (VDA) 1 item
  381. Androgen Receptor 1 item
  382. Substance P/NK1 Receptor 1 item
  383. gp120/CD4 1 item
  384. ATM 1 item
  385. Sirtuin 1 item
  386. NE 1 item
  387. PIKfyve 1 item
  388. Bax 1 item
  389. Glycogen Phosphorylases 1 item
  390. MTH1 1 item
  391. PTEN 1 item
  392. Insulin Receptor 1 item
  393. NS3/4a Proteases 1 item
  394. p90 S6K 1 item
Related Disease
  1. Acne 1 item
  2. Acute Kidney Injury 2item
  3. Acute Lung Injury 1 item
  4. Acute Myelogenous Leukemia 4item
  5. Acute Myeloid Leukemia 18item
  6. Acute Renal Failure 1 item
  7. Adrenocortical Carcinoma 3item
  8. Biliary Cancer 1 item
  9. Bladder Cancer 9item
  10. Bladder Carcinoma 3item
  11. Bladder Diseases 2item
  12. B-lymphoid Malignancies 1 item
  13. Brain Injuries Studies 3item
  14. Breast Cancer 68item
  15. Cancer 338item
  16. Castration-resistant Prostate Cancer 1 item
  17. Cervical Cancer 4item
  18. Cholangiocarcinoma 1 item
  19. Chronic Lymphocytic Leukemia 6item
  20. Chronic Myeloproliferative Disorders 1 item
  21. Clear Cell Renal Cell Carcinoma 1 item
  22. Cocaine-Related Disorders 2item
  23. Colon Cancer 22item
  24. Colon Carcinoma 3item
  25. Colorectal Cancer 28item
  26. Depression 2item
  27. Diabetes 7item
  28. Diffuse Large B-cell Lymphoma 1 item
  29. Dyskinesia 1 item
  30. Dyslipidemia 2item
  31. Epilepsy 3item
  32. Erectile Dysfunction 3item
  33. Friedreich's Ataxia 1 item
  34. Fungi 1 item
  35. Glioblastoma 18item
  36. Glioma 10item
  37. HCV 3item
  38. Heart Failure 4item
  39. Hepatitis C 3item
  40. Hepatocellular Carcinoma 4item
  41. HIV 11item
  42. HIV Infections 9item
  43. Hypercholesterolemia 1 item
  44. Inflammation 1 item
  45. Inflammatory Diseases 4item
  46. Influenza 1 item
  47. Kidney Injury Studies 2item
  48. Leukemia 16item
  49. Liver Cancer 2item
  50. Lung Cancer 19item
  51. Lung Carcinoma 2item
  52. Lymphoma 22item
  53. Mantle Cell Lymphoma 2item
  54. Melanoma 18item
  55. Mixed Lineage Leukemia 1 item
  56. Multiple Myeloma 15item
  57. Myelofibrosis 2item
  58. Myeloma 2item
  59. Neuroblastoma 6item
  60. Neurocognitive Disorders 1 item
  61. Neuronal Protection 1 item
  62. Non-small Cell Lung Cancer 15item
  63. Non-small Cell Lung Carcinoma 1 item
  64. Obsessive-Compulsive Disorder 1 item
  65. Osteoporosis 2item
  66. Ovarian Cancer 21item
  67. Pancreatic Cancer 30item
  68. Pancreatic Carcinoma 1 item
  69. Prostate Cancer 35item
  70. Psoriasis 3item
  71. Psoriasis Vulgaris 1 item
  72. Pulmonary Fibrosis 2item
  73. Renal Cancer 3item
  74. Renal Cell Carcinoma 4item
  75. Rheumatoid Arthritis 11item
  76. Sarcoma 1 item
  77. Schizophrenia 4item
  78. Sleep Disorders 1 item
  79. Soft Tissue Sarcoma 1 item
  80. Squamous Cell Carcinoma 2item
  81. Thyroid Cancer 4item
  82. Tuberculosis 1 item
  83. Type 2 Diabetes 7item