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  • Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Items 111-120 of 137

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  1. PF-562271
    A8310 PF-562271
     1 Citation
    Target: FAK|Pyk2
    Summary: ATP-competitive FAK inhibitor, reversible
      ≥25.35 mg/mL
  2. Vandetanib (ZD6474)
    A8555 Vandetanib (ZD6474)
    Target: VEGFR|EGFR
    Summary: VEGFR2/EGFR antagonist
      insoluble in H2O; ≥11.88 mg/mL
  3. BMS-777607
    A5703 BMS-777607
    Target: MET
    Summary: C-Met inhibitor, potent and selective
      ≥25.65 mg/mL
  4. PF-00562271
    A8320 PF-00562271
    Target: FAK|Pyk2
    Summary: FAK/Pyk2 inhibitor,potent and ATP-competitive
      insoluble in EtOH; insoluble in H2O; ≥11.1 mg/mL
  5. Bosutinib (SKI-606)
    A2149 Bosutinib (SKI-606)
     1 Citation
    Target: Bcr-Abl|Src
    Summary: Potent Abl/Src kinases
      ≥26.5 mg/mL
  6. SGX-523
    A1196 SGX-523
     1 Citation
    Target: MET
    Summary: MET inibitor, highly selective, ATP-competitive
      ≥17.95 mg/mL
  7. Dacomitinib (PF299804, PF299)
    A8319 Dacomitinib (PF299804, PF299)
    Target: ErbB
    Summary: HER inhibitor
      ≥23.5 mg/mL
  8. AZD8931 (Sapitinib)
    A8375 AZD8931 (Sapitinib)
    Target: EGFR|ErbB
    Summary: ErbB inhibitor
      ≥23.7 mg/mL
  9. Butein
    A2689 Butein
    Target: Src|STAT|EGFR|Angiotensin-Converting Enzymes (ACEs)|5-Lipoxygenases|PTK|enoyl-acyl-carrier protein reductase
    Summary: Protein kinase inhibitor
      insoluble in H2O; ≥13.6 mg/mL
  10. TAK-285
    A8528 TAK-285
    Target: EGFR|HER2
    Summary: HER2/EGFR(HER1) inhibitor
      ≥27.4 mg/mL

Items 111-120 of 137

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  1. Bcr-Abl 8item
  2. Axl 5item
  3. ALK 10item
  4. c-FMS 1 item
  5. c-Kit 4item
  6. c-MET 14item
  7. c-RET 4item
  8. CSF-1R 3item
  9. EGFR 21item
  10. FAK 5item
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  20. Spleen Tyrosine Kinase (Syk) 6item
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  24. VEGFR 29item
Specificity
  1. Selective 101item
Reversibility
  1. Reversible 8item
  2. Irreversible 8item
Target
  1. Histone Deacetylases (HDACs) 1 item
  2. Raf 5item
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  6. FLT3 12item
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  15. Insulin-like growth factor receptors(IGFRs) 1 item
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  35. Insulin-like growth factors (IGFs) 1 item
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  37. Angiotensin-Converting Enzymes (ACEs) 1 item
  38. Tie-2 4item
  39. RSK 1 item
  40. p70 S6K 1 item
  41. Ron 1 item
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  47. c-RET 2item
  48. TAM kinase 1 item
  49. KDR 1 item
  50. Fyn kinase 1 item
  51. AXL 1 item
  52. c-Fms tyrosine kinase 1 item
  53. insulin 1 item
  54. Mer tyrosine kinase 1 item
  55. ErbB-2 1 item
  56. ITK 1 item
  57. DCLK2 1 item
  58. PTK 1 item
  59. Flk1 1 item
  60. YES 1 item
  61. Fyn 1 item
  62. enoyl-acyl-carrier protein reductase 1 item
  63. tropomyosin receptor kinase 1 item
  64. Insulin Receptor 1 item
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