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  • Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Items 11-20 of 137

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  1. Afatinib (BIBW2992)
    A8247 Afatinib (BIBW2992)
     1 Citation
    Target: EGFR
    Summary: Irreversible EGFR/HER2 inhibitor
      ≥24.3 mg/mL
  2. Nintedanib (BIBF 1120)
    A8252 Nintedanib (BIBF 1120)
     3 Citation
    Target: VEGFR|PDGFR|FGFR
    Summary: VEGFR/PDGFR/FGFR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥5.34 mg/mL
  3. R406
    A8546 R406
     1 Citation
    Target: Syk
    Summary: SYK inhibitor,potent and ATP-competitive
      ≥31.45 mg/mL
  4. AG-490
    A4139 AG-490
     3 Citation
    Target: EGFR|JAK
    Summary: JAK2/EGFR inhibitor
      insoluble in H2O; ≥14.7 mg/mL
  5. UNC2881
    B4357 UNC2881
    Target: Mer tyrosine kinase
    Summary: Mer tyrosine kinase inhibitor
      insoluble in H2O; insoluble in EtOH; ≥13.55 mg/mL
  6. BLU9931
    A8706 BLU9931
    Target: FGFR
    Summary: FGFR4 inhibitor,potent and irreversible
      ≥50.9 mg/mL
  7. AZD-3463
    A8620 AZD-3463
     3 Citation
    Target: ALK|Insulin-like growth factors (IGFs)
    Summary: ALK/IGF1R inhibitor
      insoluble in H2O; insoluble in EtOH; ≥11.22 mg/mL
  8. Ponatinib (AP24534)
    A5467 Ponatinib (AP24534)
     1 Citation
    Target: VEGFR|PDGFR|Bcr-Abl|FGFR|Src
    Summary: pan-BCR-ABL inhibitor,multi-kinase inhibitor
      ≥53.3 mg/mL
  9. Crenolanib (CP-868596)
    A8307 Crenolanib (CP-868596)
     1 Citation
    Target: FLT3|PDGFR
    Summary: PDGFR-β inhibitor,potent and selective
      ≥22.2 mg/mL
  10. LY2801653
    A3573 LY2801653
    Target: MET
    Summary: MET inhibitor
      ≥27.65 mg/mL

Items 11-20 of 137

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  1. Category Tyrosine Kinase Remove This Item
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Category
  1. Bcr-Abl 8item
  2. Axl 5item
  3. ALK 10item
  4. c-FMS 1 item
  5. c-Kit 4item
  6. c-MET 14item
  7. c-RET 4item
  8. CSF-1R 3item
  9. EGFR 21item
  10. FAK 5item
  11. FGFR 10item
  12. FLT3 8item
  13. HER2 10item
  14. IGF1R 4item
  15. IRAK 1 item
  16. ITK 1 item
  17. LRRK2 5item
  18. PDGFR 12item
  19. Pyk2 2item
  20. Spleen Tyrosine Kinase (Syk) 6item
  21. Src 6item
  22. Tie-2 2item
  23. Trk 3item
  24. VEGFR 29item
Specificity
  1. Selective 101item
Reversibility
  1. Reversible 8item
  2. Irreversible 8item
Target
  1. Histone Deacetylases (HDACs) 1 item
  2. Raf 5item
  3. Aurora Kinases 3item
  4. CSF-1R 4item
  5. MER 1 item
  6. FLT3 12item
  7. Eph Receptors 1 item
  8. VEGFR 36item
  9. PDGFR 21item
  10. c-Kit 12item
  11. RET 3item
  12. IRAK 1 item
  13. Bcr-Abl 10item
  14. FGFR 15item
  15. Insulin-like growth factor receptors(IGFRs) 1 item
  16. MET 7item
  17. Src 9item
  18. Trk Receptors 4item
  19. STAT 1 item
  20. EGFR 21item
  21. FAK 5item
  22. BMP and Other Activin Receptors 2item
  23. JAK 2item
  24. Syk 6item
  25. ErbB 5item
  26. c-MET 8item
  27. PKC 1 item
  28. Lyn 2item
  29. HER2 3item
  30. Pyk2 3item
  31. LRRK2 5item
  32. Insulin and Insulin-like Receptors 3item
  33. ALK 6item
  34. ROS1 2item
  35. Insulin-like growth factors (IGFs) 1 item
  36. CSF1R 1 item
  37. Angiotensin-Converting Enzymes (ACEs) 1 item
  38. Tie-2 4item
  39. RSK 1 item
  40. p70 S6K 1 item
  41. Ron 1 item
  42. 5-Lipoxygenases 1 item
  43. Insulin Receptors 1 item
  44. IRG-1R 1 item
  45. ZAP-70 1 item
  46. Flk-1 1 item
  47. c-RET 2item
  48. TAM kinase 1 item
  49. KDR 1 item
  50. Fyn kinase 1 item
  51. AXL 1 item
  52. c-Fms tyrosine kinase 1 item
  53. insulin 1 item
  54. Mer tyrosine kinase 1 item
  55. ErbB-2 1 item
  56. ITK 1 item
  57. DCLK2 1 item
  58. PTK 1 item
  59. Flk1 1 item
  60. YES 1 item
  61. Fyn 1 item
  62. enoyl-acyl-carrier protein reductase 1 item
  63. tropomyosin receptor kinase 1 item
  64. Insulin Receptor 1 item
Related Disease
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  3. Adrenocortical Carcinoma 1 item
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