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Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Items 221-230 of 325

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  1. PF-562271 HCl
    A8345 PF-562271 HCl
    Target: FAK|Pyk2
    Summary: FAK/Pyk2 inhibitor
      ≥26.35 mg/mL
  2. ALK-IN-1
    A1367 ALK-IN-1
    Summary: Anaplastic lymphoma kinase (ALK) inhibitor
      ≥26.45 mg/mL
  3. Regorafenib
    A8236 Regorafenib
     4 Citation
    Target: Raf|VEGFR|PDGFR|c-Kit|RET
    Summary: Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1
      ≥25.04 mg/mL
  4. LDK378 dihydrochloride
    A3544 LDK378 dihydrochloride
    Summary: ALK inhibitor
  5. Toceranib
    A3879 Toceranib
    Summary: c-Kit/VEGFR/PDGFR inhibtor
      soluble in DMSO
  6. PF-562271
    A8310 PF-562271
     1 Citation
    Target: FAK|Pyk2
    Summary: ATP-competitive FAK inhibitor, reversible
      ≥25.35 mg/mL
  7. Vandetanib (ZD6474)
    A8555 Vandetanib (ZD6474)
    Target: VEGFR|EGFR
    Summary: VEGFR2/EGFR antagonist
      insoluble in H2O; ≥11.88 mg/mL
  8. BMS-777607
    A5703 BMS-777607
    Target: MET
    Summary: C-Met inhibitor, potent and selective
      ≥25.65 mg/mL
  9. PF-00562271
    A8320 PF-00562271
    Target: FAK|Pyk2
    Summary: FAK/Pyk2 inhibitor,potent and ATP-competitive
      insoluble in EtOH; insoluble in H2O; ≥11.1 mg/mL
  10. WZ4002
    A1389 WZ4002
    Summary: Mutant-selective EGFR inhibitor(L858R,T790M), irreversible and potent
      ≥24.7 mg/mL

Items 221-230 of 325

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  1. Bcr-Abl 18item
  2. Ack1 1 item
  3. Axl 6item
  4. ALK 21item
  5. BMX Kinase 1 item
  6. Broad Spectrum Protein Kinase Inhibitor 8item
  7. c-FMS 2item
  8. c-Kit 7item
  9. c-MET 24item
  10. c-RET 7item
  11. CSF-1R 3item
  12. DDR1/DDR2 Receptor 1 item
  13. EGFR 66item
  14. EphB4 1 item
  15. FAK 10item
  16. FGFR 17item
  17. FLT3 18item
  18. HER2 14item
  19. IGF1R 9item
  20. Insulin Receptor 2item
  21. IRAK 6item
  22. ITK 1 item
  23. Lck 1 item
  24. LRRK2 9item
  25. PDGFR 24item
  26. PTKs/RTKs 3item
  27. Pyk2 3item
  28. Spleen Tyrosine Kinase (Syk) 12item
  29. Src 22item
  30. Tie-2 2item
  31. Trk 4item
  32. VEGFR 54item
Specificity
  1. Selective 113item
Reversibility
  1. Reversible 8item
  2. Irreversible 8item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 1 item
  3. Raf 5item
  4. Aurora Kinases 3item
  5. CSF-1R 4item
  6. MER 1 item
  7. FLT3 12item
  8. Eph Receptors 2item
  9. VEGFR 36item
  10. PDGFR 23item
  11. c-Kit 12item
  12. RET 3item
  13. IRAK 5item
  14. Bcr-Abl 12item
  15. FGFR 15item
  16. Insulin-like growth factor receptors(IGFRs) 1 item
  17. MET 7item
  18. Src 12item
  19. Trk Receptors 4item
  20. STAT 1 item
  21. EGFR 23item
  22. FAK 5item
  23. BMP and Other Activin Receptors 3item
  24. JAK 2item
  25. Syk 6item
  26. ErbB 5item
  27. Kinases 1 item
  28. c-MET 8item
  29. PKC 2item
  30. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  31. Lyn 2item
  32. HER2 3item
  33. Pyk2 3item
  34. LRRK2 5item
  35. Insulin and Insulin-like Receptors 3item
  36. ALK 6item
  37. ROS1 2item
  38. PKG 1 item
  39. PKA 1 item
  40. Myosin light chain kinases (MLCKs) 1 item
  41. Insulin-like growth factors (IGFs) 1 item
  42. CSF1R 1 item
  43. Angiotensin-Converting Enzymes (ACEs) 1 item
  44. Tie-2 4item
  45. RSK 1 item
  46. p70 S6K 1 item
  47. Ron 1 item
  48. c-Fyn 1 item
  49. 5-Lipoxygenases 1 item
  50. Insulin Receptors 1 item
  51. IRG-1R 1 item
  52. ZAP-70 1 item
  53. Flk-1 1 item
  54. c-RET 2item
  55. TAM kinase 1 item
  56. KDR 1 item
  57. Fyn kinase 1 item
  58. Abl kinases 1 item
  59. AXL 1 item
  60. c-Fms tyrosine kinase 1 item
  61. insulin 1 item
  62. Mer tyrosine kinase 1 item
  63. ErbB-2 1 item
  64. ITK 1 item
  65. DCLK2 1 item
  66. PTK 1 item
  67. Flk1 1 item
  68. YES 1 item
  69. Fyn 1 item
  70. enoyl-acyl-carrier protein reductase 1 item
  71. tropomyosin receptor kinase 1 item
  72. Insulin Receptor 1 item
Reported Experiments
  1. Animal Experiments 137item
  2. Cell Experiments 97item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 5item
  3. Adrenocortical Carcinoma 1 item
  4. Advanced Renal Cell Carcinoma 1 item
  5. Autoimmune Diseases 1 item
  6. Bladder Cancer 4item
  7. Bladder Carcinoma 1 item
  8. Breast Cancer 21item
  9. Cancer 108item
  10. Cervical Cancer 1 item
  11. Cholangiocarcinoma 1 item
  12. Chronic Lymphocytic Leukemia 1 item
  13. Clear Cell Renal Cell Carcinoma 1 item
  14. Colon Cancer 4item
  15. Colon Carcinoma 3item
  16. Colorectal Cancer 12item
  17. Glioblastoma 9item
  18. Glioma 4item
  19. Hepatocellular Carcinoma 3item
  20. Leukemia 3item
  21. Liver Cancer 2item
  22. Lung Cancer 8item
  23. Lung Carcinoma 4item
  24. Lymphoma 5item
  25. Melanoma 3item
  26. Multiple Myeloma 5item
  27. Myeloma 1 item
  28. Neuroblastoma 2item
  29. Non-small Cell Lung Cancer 6item
  30. Ovarian Cancer 8item
  31. Pancreatic Cancer 12item
  32. Prostate Cancer 7item
  33. Pulmonary Arterial Hypertension 1 item
  34. Renal Cancer 2item
  35. Renal Cell Carcinoma 4item
  36. Rheumatoid Arthritis 2item
  37. Thyroid Cancer 4item