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  • Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Items 71-80 of 137

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  1. Lapatinib Ditosylate
    A3967 Lapatinib Ditosylate
    Target: EGFR|ErbB-2
    Summary: EGFR/HER2 inhibitor,potent and selective
      ≥24.3 mg/mL
  2. FIIN-2
    A8696 FIIN-2
    Target: FGFR
    Summary: Irreversible inhibitor of FGFR
      ≥31.75 mg/mL
  3. NVP-AEW541
    A2278 NVP-AEW541
    Target: Insulin Receptor
    Summary: IGF-IR inhibitor, novel, potent and selective
      ≥22 mg/mL
  4. Motesanib
    A3632 Motesanib
    Target: VEGFR
    Summary: Inhibitor of Flk-1/Flt-4/PDGFR-/c-Kit
      ≥42 mg/mL
  5. Saracatinib (AZD0530)
    A2133 Saracatinib (AZD0530)
     3 Citation
    Target: Src
    Summary: Src/Abl inhibitor,potent and selective
      ≥27.1 mg/mL
  6. Masitinib (AB1010)
    A2942 Masitinib (AB1010)
    Target: PDGFR|c-Kit|Lyn
    Summary: Tyrosine kinase inhibitor, potent and selective
      ≥24.95 mg/mL
  7. LRRK2-IN-1
    A3558 LRRK2-IN-1
     1 Citation
    Target: LRRK2|DCLK2
    Summary: LRRK2 inhibitor,cell-permeable and ATP competitive
      ≥28.55 mg/mL
  8. Dovitinib (TKI-258, CHIR-258)
    A2168 Dovitinib (TKI-258, CHIR-258)
     2 Citation
    Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Multitargeted RTK inhibitor
      insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
  9. PF-04217903
    A5096 PF-04217903
    Target: c-MET
    Summary: C-Met inhibitor,selective and ATP-competitive
      insoluble in EtOH; insoluble in H2O; ≥18.6 mg/mL
  10. AZD4547
    A8350 AZD4547
    Target: FGFR
    Summary: FGFR inhibitor
      ≥23.2 mg/mL

Items 71-80 of 137

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  1. Category Tyrosine Kinase Remove This Item
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Category
  1. Bcr-Abl 8item
  2. Axl 5item
  3. ALK 10item
  4. c-FMS 1 item
  5. c-Kit 4item
  6. c-MET 14item
  7. c-RET 4item
  8. CSF-1R 3item
  9. EGFR 21item
  10. FAK 5item
  11. FGFR 10item
  12. FLT3 8item
  13. HER2 10item
  14. IGF1R 4item
  15. IRAK 1 item
  16. ITK 1 item
  17. LRRK2 5item
  18. PDGFR 12item
  19. Pyk2 2item
  20. Spleen Tyrosine Kinase (Syk) 6item
  21. Src 6item
  22. Tie-2 2item
  23. Trk 3item
  24. VEGFR 29item
Specificity
  1. Selective 101item
Reversibility
  1. Reversible 8item
  2. Irreversible 8item
Target
  1. Histone Deacetylases (HDACs) 1 item
  2. Raf 5item
  3. Aurora Kinases 3item
  4. CSF-1R 4item
  5. MER 1 item
  6. FLT3 12item
  7. Eph Receptors 1 item
  8. VEGFR 36item
  9. PDGFR 21item
  10. c-Kit 12item
  11. RET 3item
  12. IRAK 1 item
  13. Bcr-Abl 10item
  14. FGFR 15item
  15. Insulin-like growth factor receptors(IGFRs) 1 item
  16. MET 7item
  17. Src 9item
  18. Trk Receptors 4item
  19. STAT 1 item
  20. EGFR 21item
  21. FAK 5item
  22. BMP and Other Activin Receptors 2item
  23. JAK 2item
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  25. ErbB 5item
  26. c-MET 8item
  27. PKC 1 item
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  30. Pyk2 3item
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  32. Insulin and Insulin-like Receptors 3item
  33. ALK 6item
  34. ROS1 2item
  35. Insulin-like growth factors (IGFs) 1 item
  36. CSF1R 1 item
  37. Angiotensin-Converting Enzymes (ACEs) 1 item
  38. Tie-2 4item
  39. RSK 1 item
  40. p70 S6K 1 item
  41. Ron 1 item
  42. 5-Lipoxygenases 1 item
  43. Insulin Receptors 1 item
  44. IRG-1R 1 item
  45. ZAP-70 1 item
  46. Flk-1 1 item
  47. c-RET 2item
  48. TAM kinase 1 item
  49. KDR 1 item
  50. Fyn kinase 1 item
  51. AXL 1 item
  52. c-Fms tyrosine kinase 1 item
  53. insulin 1 item
  54. Mer tyrosine kinase 1 item
  55. ErbB-2 1 item
  56. ITK 1 item
  57. DCLK2 1 item
  58. PTK 1 item
  59. Flk1 1 item
  60. YES 1 item
  61. Fyn 1 item
  62. enoyl-acyl-carrier protein reductase 1 item
  63. tropomyosin receptor kinase 1 item
  64. Insulin Receptor 1 item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 5item
  3. Adrenocortical Carcinoma 1 item
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  9. Cancer 104item
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