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  • Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Items 71-80 of 113

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  1. Dovitinib (TKI-258, CHIR-258)
    A2168 Dovitinib (TKI-258, CHIR-258)
     2 Citation
    Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Multitargeted RTK inhibitor
      insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
  2. PF-04217903
    A5096 PF-04217903
    Target: c-MET
    Summary: C-Met inhibitor,selective and ATP-competitive
      insoluble in EtOH; insoluble in H2O; ≥18.6 mg/mL
  3. AZD4547
    A8350 AZD4547
    Target: FGFR
    Summary: FGFR inhibitor
      ≥23.2 mg/mL
  4. MK-2461
    A8476 MK-2461
    Target: FLT3|PDGFR|MET|Ron
    Summary: C-Met (WT/mutants) inhibitor
      ≥24.8 mg/mL
  5. Tivantinib (ARQ 197)
    A8325 Tivantinib (ARQ 197)
     2 Citation
    Target: MET
    Summary: C-Met inhibitor,non-ATP-competitive
      ≥18.47 mg/mL
  6. LDC1267
    B4893 LDC1267
    Target: TAM kinase
    Summary: TAM kinase inhibitor,highly selective
      insoluble in H2O; insoluble in EtOH; ≥20.75 mg/mL
  7. Gefitinib (ZD1839)
    A8219 Gefitinib (ZD1839)
     3 Citation
    Target: EGFR
    Summary: Selective EGFR inhibitor
      ≥22.34 mg/mL
  8. Ki20227
    A3527 Ki20227
    Target: c-Fms tyrosine kinase
    Summary: C-Fms tyrosine kinase inhibitor
      ≥48.1 mg/mL
  9. SU 5402
    A3843 SU 5402
    Target: VEGFR|PDGFR|FGFR
    Summary: VEGFR2/FGFR/PDGFR/EGFR inhibitor
      insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL
  10. Quizartinib (AC220)
    A5793 Quizartinib (AC220)
    Target: FLT3
    Summary: FLT3 inhibitor,potent and selective
      ≥28.03 mg/mL

Items 71-80 of 113

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  1. Category Tyrosine Kinase Remove This Item
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Category
  1. Bcr-Abl 5item
  2. Axl 4item
  3. ALK 9item
  4. Broad Spectrum Protein Kinase Inhibitor 1 item
  5. c-FMS 1 item
  6. c-Kit 3item
  7. c-MET 13item
  8. c-RET 2item
  9. CSF-1R 3item
  10. EGFR 14item
  11. EphB4 1 item
  12. FAK 4item
  13. FGFR 8item
  14. FLT3 6item
  15. HER2 5item
  16. IGF1R 4item
  17. IRAK 3item
  18. ITK 1 item
  19. LRRK2 4item
  20. PDGFR 12item
  21. Pyk2 2item
  22. Spleen Tyrosine Kinase (Syk) 6item
  23. Src 5item
  24. Tie-2 2item
  25. Trk 3item
  26. VEGFR 18item
Reversibility
  1. Reversible 7item
  2. Irreversible 4item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Raf 3item
  3. Aurora Kinases 1 item
  4. CSF-1R 2item
  5. MER 1 item
  6. FLT3 9item
  7. Eph Receptors 2item
  8. VEGFR 24item
  9. PDGFR 16item
  10. c-Kit 7item
  11. RET 3item
  12. IRAK 3item
  13. Bcr-Abl 8item
  14. FGFR 9item
  15. Insulin-like growth factor receptors(IGFRs) 1 item
  16. MET 7item
  17. Src 7item
  18. Trk Receptors 4item
  19. EGFR 14item
  20. FAK 4item
  21. BMP and Other Activin Receptors 3item
  22. JAK 2item
  23. Syk 6item
  24. ErbB 2item
  25. c-MET 8item
  26. PKC 1 item
  27. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  28. Lyn 1 item
  29. HER2 2item
  30. Pyk2 3item
  31. LRRK2 4item
  32. Insulin and Insulin-like Receptors 2item
  33. ALK 4item
  34. ROS1 2item
  35. PKG 1 item
  36. PKA 1 item
  37. Myosin light chain kinases (MLCKs) 1 item
  38. Insulin-like growth factors (IGFs) 1 item
  39. CSF1R 1 item
  40. Tie-2 3item
  41. RSK 1 item
  42. p70 S6K 1 item
  43. Ron 1 item
  44. c-Fyn 1 item
  45. Insulin Receptors 1 item
  46. IRG-1R 1 item
  47. ZAP-70 1 item
  48. Flk-1 1 item
  49. TAM kinase 1 item
  50. AXL 1 item
  51. c-Fms tyrosine kinase 1 item
  52. ITK 1 item
  53. DCLK2 1 item
  54. tropomyosin receptor kinase 1 item
  55. Insulin Receptor 1 item
Reported Experiments
  1. Animal Experiments 101item
  2. Cell Experiments 59item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 5item
  3. Adrenocortical Carcinoma 1 item
  4. Advanced Renal Cell Carcinoma 1 item
  5. Autoimmune Diseases 1 item
  6. Bladder Cancer 4item
  7. Bladder Carcinoma 1 item
  8. Breast Cancer 19item
  9. Cancer 82item
  10. Cervical Cancer 1 item
  11. Cholangiocarcinoma 1 item
  12. Chronic Lymphocytic Leukemia 1 item
  13. Clear Cell Renal Cell Carcinoma 1 item
  14. Colon Cancer 3item
  15. Colon Carcinoma 3item
  16. Colorectal Cancer 12item
  17. Glioblastoma 9item
  18. Glioma 4item
  19. Hepatocellular Carcinoma 3item
  20. Leukemia 2item
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  22. Lung Cancer 8item
  23. Lung Carcinoma 4item
  24. Lymphoma 5item
  25. Melanoma 3item
  26. Multiple Myeloma 5item
  27. Myeloma 1 item
  28. Neuroblastoma 2item
  29. Non-small Cell Lung Cancer 6item
  30. Ovarian Cancer 7item
  31. Pancreatic Cancer 12item
  32. Prostate Cancer 7item
  33. Pulmonary Arterial Hypertension 1 item
  34. Renal Cancer 2item
  35. Renal Cell Carcinoma 4item
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  37. Thyroid Cancer 4item