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  • Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Search results for: 'research area pi3k akt signaling pi3k inhibitors'

9 Items

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  1. DCC-2036 (Rebastinib)
    B1404 DCC-2036 (Rebastinib)
    Target: FLT3|Bcr-Abl|Tie-2|KDR
    Summary: Bcr-Abl inhibitor
      ≥27.7 mg/mL
  2. G-749
    A8889 G-749
    Target: Aurora Kinases|FLT3|c-RET
    Summary: FLT3 inhibitor
      ≥26.05 mg/mL
  3. UNC2025
    B8016 UNC2025
     1 Citation
    Target: MER|FLT3
    Summary: orally bioavailable dual MER/FLT3 inhibitor
      ≥23.85 mg/mL
  4. Dovitinib (TKI-258, CHIR-258)
    A2168 Dovitinib (TKI-258, CHIR-258)
     2 Citation
    Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Multitargeted RTK inhibitor
      insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
  5. MK-2461
    A8476 MK-2461
    Target: FLT3|PDGFR|MET|Ron
    Summary: C-Met (WT/mutants) inhibitor
      ≥24.8 mg/mL
  6. Quizartinib (AC220)
    A5793 Quizartinib (AC220)
    Target: FLT3
    Summary: FLT3 inhibitor,potent and selective
      ≥28.03 mg/mL
  7. Altiratinib
    B5832 Altiratinib
     1 Citation
    Target: FLT3|VEGFR|Trk Receptors|c-MET|Tie-2
    Summary: c-MET/TIE-2/VEGFR inhibitor
      ≥21.55 mg/mL
  8. AZD2932
    B5835 AZD2932
    Target: FLT3|VEGFR|PDGFR|c-Kit
    Summary: inhibitor of VEGFR-2, PDGFRβ, Flt-3, and c-Kit
      Soluble in DMSO
  9. Dovitinib (TKI258) Lactate
    B5953 Dovitinib (TKI258) Lactate
    Target: CSF-1R|FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Oral tyrosine kinase inhibitor (TKI) against FGFR1–3, VEGFR1–3, and platelet-derived growth factor receptor (PDGFR).
      insoluble in EtOH; ≥10.62 mg/mL

9 Items

per page