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  • Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Items 1-10 of 83

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  1. Rigosertib
    B1288 Rigosertib
    Target: PI3K|PLK
    Summary: PI3K/PLK1 inhibitor
      Soluble in DMSO
  2. SLx-2119
    A3825 SLx-2119
     1 Citation
    Target: ROCK
    Summary: Selective ROCK2 inhibitor
      ≥22.65 mg/mL
  3. CCG-1423
    B4897 CCG-1423
    Target: Rho
    Summary: RhoA inhibitor
      ≥21 mg/mL
  4. CYC116
    A4125 CYC116
    Target: Aurora Kinases|FLT3|VEGFR
    Summary: Potent Aurora A/B inhibitor
      insoluble in EtOH; insoluble in H2O; ≥18.4 mg/mL
  5. MLN8054
    A4114 MLN8054
    Target: Aurora Kinases
    Summary: Aurora A inhibitor
      insoluble in EtOH; insoluble in H2O; ≥39.05 mg/mL
  6. Fasudil (HA-1077) HCl
    A5734 Fasudil (HA-1077) HCl
     1 Citation
    Target: ROCK
    Summary: Protein kinase inhibitor
      ≥16.4 mg/mL
  7. IPA-3
    B2169 IPA-3
     1 Citation
    Target: PAK
    Summary: Non-ATP competitive Pak1 inhibitor
      insoluble in H2O; ≥16.1 mg/mL
  8. MLN0905
    A8680 MLN0905
    Target: PLK
    Summary: Potent PLK1 inhibitor
      ≥24.35 mg/mL
  9. LEE011
    A8641 LEE011
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥10.88 mg/mL
  10. VE-822
    B1383 VE-822
     2 Citation
    Target: ATM/ATR
    Summary: ATR inhibitor
      ≥50 mg/mL

Items 1-10 of 83

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Category
  1. ATM/ATR 3item
  2. Aurora Kinase 18item
  3. Cdc42 1 item
  4. Cdc7 1 item
  5. Chk 7item
  6. CRM1 1 item
  7. Cyclin-Dependent Kinases 21item
  8. E1 enzyme 1 item
  9. Ksp 2item
  10. Microtubule/Tubulin 4item
  11. RAD51 2item
  12. ROCK 7item
  13. Rho 2item
  14. PAK1 2item
  15. PAK4 1 item
  16. PERK 1 item
  17. PLK 9item
  18. PTEN 1 item
Specificity
  1. Selective 57item
Reversibility
  1. Reversible 7item
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 23item
  2. PI3K 1 item
  3. Aurora Kinases 17item
  4. FLT3 5item
  5. GSK-3 1 item
  6. PLK 10item
  7. Chk 7item
  8. VEGFR 1 item
  9. PDGFR 1 item
  10. RET 1 item
  11. Bromodomain-containing proteins(BRDs) 1 item
  12. FGFR 1 item
  13. Src 2item
  14. Microtubules/Tubulins 2item
  15. ROCK 7item
  16. PAK 3item
  17. JAK 1 item
  18. Ksp 2item
  19. PKC 1 item
  20. RAD51 2item
  21. LRRK2 1 item
  22. PKG 1 item
  23. PKA 1 item
  24. Myosin light chain kinases (MLCKs) 1 item
  25. MK2 1 item
  26. ATM/ATR 3item
  27. Cdc42 1 item
  28. Hck 1 item
  29. Cdc7 1 item
  30. Ubiquitin-activating Enzyme E1 1 item
  31. Microtubule/Tubulin 1 item
  32. VEGFR3/FLT4 1 item
  33. NTRK1/TRKA 1 item
  34. CSF-1R/c-Fms 1 item
  35. nuclear export 1 item
  36. CRM1 1 item
  37. Hec1 1 item
  38. Histone Acetyltransferases (HATs) 1 item
  39. Rho 1 item
  40. FGR 1 item
  41. YES 1 item
  42. Fyn 1 item
  43. ARG 1 item
  44. Rho-kinase 1 item
  45. PTEN 1 item
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  3. Breast Cancer 11item
  4. Cancer 63item
  5. Cervical Cancer 1 item
  6. Chronic Lymphocytic Leukemia 2item
  7. Colon Cancer 8item
  8. Colon Carcinoma 1 item
  9. Colorectal Cancer 4item
  10. Glioblastoma 2item
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  12. Leukemia 1 item
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  14. Lung Cancer 5item
  15. Lymphoma 3item
  16. Mantle Cell Lymphoma 1 item
  17. Melanoma 2item
  18. Multiple Myeloma 1 item
  19. Neuroblastoma 1 item
  20. Non-small Cell Lung Carcinoma 1 item
  21. Ovarian Cancer 6item
  22. Pancreatic Cancer 6item
  23. Prostate Cancer 4item
  24. Renal Cell Carcinoma 1 item
  25. Thyroid Cancer 1 item