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Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Search results for: 'research area pi3k akt signaling pi3k inhibitors'

A8549 LY335979 (Zosuquidar 3HCL)

1 Citation

Target: P-glycoprotein (P-gp)

Summary: Pgp (P-glycoprotein) inhibitor

insoluble in EtOH; ≥17.1 mg/mL
A8553 PTC124 (Ataluren)

Summary: CFTR-G542X nonsense allele inhibitor

insoluble in H2O; ≥10.6 mg/mL
A3185 AR-C155858

Target: Monocarboxylate transporters (MCTs)

Summary: MCT1 and MCT2 inhibitor

insoluble in H2O; ≥52.5 mg/mL
A3859 Tariquidar methanesulfonate, hydrate

Target: P-glycoprotein (P-gp)

Summary: P-glycoprotein inhibitor, potent and selective

insoluble in H2O; insoluble in EtOH; ≥56.2 mg/mL
A8435 Furosemide

Target: Na /K /Cl- Symporters (NKCCs)|GABAA Receptors

Summary: GABAA receptors antagonist
B2194 Tolbutamide

Target: cAMP|Sulfonylurea receptors

Summary: first generation potassium channel blocker

insoluble in H2O; ≥10.05 mg/mL
A1888 TRAM-34

Target: Calcium-Activated Potassium (KCa) Channels

Summary: KCa3.1 blocker,potent and highly selective

insoluble in H2O; insoluble in EtOH; ≥17.25 mg/mL
A1855 Bumetanide

Target: Na /K /Cl- Symporters (NKCCs)

Summary: NKCC cotransporter inhibitor

insoluble in H2O; ≥36.37 mg/mL
A8417 Dofetilide

2 Citation

Target: Delayed rectifier outward potassium current (IKr)

Summary: Potassium channel inhibitor

≥21.15 mg/mL
B2193 Mitiglinide Calcium

Target: Inward Rectifier Potassium (Kir) Channels

Summary: Potassium channel inhibitor

≥33.45 mg/mL