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  • Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Items 11-20 of 116

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  1. Valproic acid sodium salt (Sodium valproate)
    A4099 Valproic acid sodium salt (Sodium valproate)
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor
      ≥8.35 mg/mL
  2. PCI-24781 (CRA-024781)
    A4098 PCI-24781 (CRA-024781)
    Target: Histone Deacetylases (HDACs)
    Summary: Pan-HDAC inhibitor
      insoluble in H2O; insoluble in EtOH; ≥11.75 mg/mL
  3. WP1066
    A4140 WP1066
    Target: STAT|JAK
    Summary: JAK2/STAT3 inhibitor,cell-permeable
      insoluble in H2O; ≥17.8 mg/mL
  4. XAV-939
    A1877 XAV-939
     1 Citation
    Target: TNKS
    Summary: Tankyrase 1/2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥15.62 mg/mL
  5. Pyridone 6
    A3741 Pyridone 6
    Target: JAK
    Summary: Pan-JAK inhibitor
      insoluble in H2O; ≥15.45 mg/mL
  6. EX 527 (SEN0014196)
    A4181 EX 527 (SEN0014196)
     1 Citation
    Target: Sirtuin
    Summary: SIRT1 inhibitor
      insoluble in H2O; ≥12.43 mg/mL
  7. Entinostat (MS-275,SNDX-275)
    A8171 Entinostat (MS-275,SNDX-275)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC1 and HDAC3 inhibitor
      insoluble in H2O; ≥18.8 mg/mL
  8. Tofacitinib (CP-690550) Citrate
    A4135 Tofacitinib (CP-690550) Citrate
     2 Citation
    Target: JAK
    Summary: Potent JAK inhibitor
      ≥25.22 mg/mL
  9. CYC116
    A4125 CYC116
    Target: Aurora Kinases|FLT3|VEGFR
    Summary: Potent Aurora A/B inhibitor
      insoluble in EtOH; insoluble in H2O; ≥18.4 mg/mL
  10. I-BET151 (GSK1210151A)
    B1500 I-BET151 (GSK1210151A)
     2 Citation
    Target: Bromodomain and Extra-Terminal motif (BET)
    Summary: Selective BET inhibitor
      ≥41.5 mg/mL

Items 11-20 of 116

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Category
  1. Bromodomain 8item
  2. Aurora Kinase 18item
  3. DNA Methyltransferase 3item
  4. HDAC 33item
  5. Histone Acetyltransferases 2item
  6. Histone Demethylases 2item
  7. Histone Methyltransferase 11item
  8. HIF 5item
  9. JAK 18item
  10. PARP 8item
  11. Pim 2item
  12. Protein Ser/Thr Phosphatases 2item
  13. Sirtuin 4item
  14. Sphingosine Kinase-2 1 item
Specificity
  1. Selective 84item
Reversibility
  1. Reversible 6item
  2. Irreversible 2item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 30item
  3. PI3K 1 item
  4. Aurora Kinases 18item
  5. EZH2 2item
  6. Bromodomains 6item
  7. FLT3 5item
  8. PLK 1 item
  9. VEGFR 3item
  10. RET 1 item
  11. Hydrolase 1 item
  12. DOT1L 3item
  13. FGFR 2item
  14. Nrf2 1 item
  15. Pim 2item
  16. Sir2-like Family Deacetylases (Sirtuins) 3item
  17. Src 3item
  18. Trk Receptors 1 item
  19. STAT 2item
  20. EGFR 2item
  21. Hypoxia Inducible Factors (HIFs) 2item
  22. Tankyrases 1 item
  23. JAK 18item
  24. p300 1 item
  25. Syk 1 item
  26. EZH1 1 item
  27. TNKS 1 item
  28. ErbB 1 item
  29. DNA Methyltransferases 2item
  30. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  31. CREBBP 1 item
  32. EP300 1 item
  33. LRRK2 1 item
  34. PARP 6item
  35. ALK 1 item
  36. Bromodomain and Extra-Terminal motif (BET) 1 item
  37. phosphatases 1 item
  38. G9a 1 item
  39. Hck 1 item
  40. MNK 1 item
  41. AChE 1 item
  42. Catechol O-Methyltransferase (COMT) 1 item
  43. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  44. Protein Arginine Methyltransferases 1 item
  45. Cytidine deaminases 1 item
  46. c-RET 1 item
  47. VEGFR3/FLT4 1 item
  48. NTRK1/TRKA 1 item
  49. CSF-1R/c-Fms 1 item
  50. PTP 1 item
  51. p53 1 item
  52. HDAC 2item
  53. Histone Acetyltransferases (HATs) 1 item
  54. Trx 1 item
  55. HIF-PH 1 item
  56. TYK2 2item
  57. MUSK 1 item
  58. MAP3K 1 item
  59. p21 1 item
  60. FGR 1 item
  61. YES 1 item
  62. Fyn 1 item
  63. ARG 1 item
  64. LSD 1 item
  65. PRMT 1 item
  66. GLP 1 item
  67. SK 1 item
  68. Sirtuin 1 item
Related Disease
  1. Acute Myelogenous Leukemia 2item
  2. Acute Myeloid Leukemia 8item
  3. Bladder Cancer 2item
  4. Bladder Carcinoma 1 item
  5. Breast Cancer 17item
  6. Cancer 74item
  7. Castration-resistant Prostate Cancer 1 item
  8. Cervical Cancer 2item
  9. Chronic Lymphocytic Leukemia 1 item
  10. Colon Cancer 10item
  11. Colon Carcinoma 1 item
  12. Colorectal Cancer 4item
  13. Diffuse Large B-cell Lymphoma 1 item
  14. Dyskinesia 1 item
  15. Epilepsy 1 item
  16. Friedreich's Ataxia 1 item
  17. Glioblastoma 2item
  18. Glioma 2item
  19. Hepatic Cancer 1 item
  20. Hepatocellular Carcinoma 1 item
  21. HIV 2item
  22. HIV Infections 2item
  23. Immunological Diseases 1 item
  24. Inflammatory Bowel Disease 1 item
  25. Inflammatory Diseases 3item
  26. Leukemia 7item
  27. Lung Cancer 6item
  28. Lymphoma 5item
  29. Melanoma 3item
  30. Mixed Lineage Leukemia 3item
  31. Multiple Myeloma 5item
  32. Myelofibrosis 1 item
  33. Myeloma 1 item
  34. Neuroblastoma 2item
  35. Neuronal Protection 1 item
  36. Non-small Cell Lung Cancer 5item
  37. Ovarian Cancer 4item
  38. Pancreatic Cancer 4item
  39. Prostate Cancer 11item
  40. Psoriasis 1 item
  41. Renal Cancer 1 item
  42. Renal Cell Carcinoma 2item
  43. Rheumatoid Arthritis 3item
  44. Thyroid Cancer 1 item