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  • Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Search results for: 'research area pi3k akt signaling pi3k inhibitors'

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  1. GDC-0068 (RG7440)
    A3006 GDC-0068 (RG7440)
    Target: Akt
    Summary: Pan-AKT inhibitor,highly selective
      ≥22.9 mg/mL
  2. TIC10
    A8619 TIC10
    Summary: Potent Akt/ERK inhibitor
  3. TGX-221
    A2681 TGX-221
    Target: PI3K
    Summary: PI3Kβ inhibitor,potent,selective and ATP competitive
      insoluble in H2O; insoluble in EtOH; ≥68.7 mg/mL
  4. AZD8055
    A8214 AZD8055
     2 Citation
    Target: mTOR
    Summary: MTOR inhibitor
      ≥23.3 mg/mL
  5. TG100-115
    A2754 TG100-115
    Target: PI3K
    Summary: PI3Kγ/PI3Kδ inhibitor
      insoluble in H2O; insoluble in EtOH; ≥3.46 mg/mL
  6. DiscoveryProbe™ NF-κB Signaling Compound Library Plus
    L1044P DiscoveryProbe™ NF-κB Signaling Compound Library Plus
    Summary: A unique collection of 178 NF-κB inhibitors for NF-κB signaling pathway research.
  7. Everolimus (RAD001)
    A8169 Everolimus (RAD001)
     8 Citation
    Target: mTOR
    Summary: MTOR inhibitor
      ≥47.91 mg/mL
  8. A-443654
    A3135 A-443654
    Summary: Akt inhibitor,potent and selective
      insoluble in H2O; ≥19.85 mg/mL
  9. PI-103 Hydrochloride
    A3724 PI-103 Hydrochloride
    Target: PI3K|mTOR|DNA-PK
    Summary: DNA-PK/PI 3-kinase/mTOR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥19.25 mg/mL
  10. VS-5584 (SB2343)
    A3927 VS-5584 (SB2343)
    Target: PI3K|mTOR
    Summary: MTOR/P13K inhibitor,potent and selective
      insoluble in H2O; ≥17.7 mg/mL

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  1. Selective 810item
  2. Non-Selective 5item
Reversibility
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  2. Irreversible 39item
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  174. Myosin light chain kinases (MLCKs) 3item
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  219. GpIIb/IIIa receptor 1 item
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  223. Farnesyltransferase 1 item
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  234. G9a 2item
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  236. HSV 2item
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  238. Calcium-activated chloride channels (CaCC) 1 item
  239. GPR35 1 item
  240. Urokinases 1 item
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  245. TAK1 1 item
  246. Histamine H1 Receptors 3item
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  250. Inositol-requiring enzyme 1 (IRE1) 3item
  251. SETD7 1 item
  252. Na /K /Cl- Symporters (NKCCs) 2item
  253. GABAA Receptors 1 item
  254. Phospholipases 1 item
  255. Monoamine oxidases (MAOs) 1 item
  256. Organic anion transporters (OATs) 1 item
  257. TRP Channel 1 item
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  274. Calcium-Activated Potassium (KCa) Channels 2item
  275. AChE 3item
  276. Insulin Receptors 1 item
  277. IRG-1R 1 item
  278. Proton Pump 1 item
  279. cAMP 1 item
  280. Sulfonylurea receptors 1 item
  281. Cdc2-like kinase (Clk) 1 item
  282. eEF-2 1 item
  283. Inward Rectifier Potassium (Kir) Channels 3item
  284. Arp2/3 complex 1 item
  285. Cdc7 1 item
  286. CMV 1 item
  287. ZAP-70 1 item
  288. Catechol O-Methyltransferase (COMT) 2item
  289. fibrinolysis 1 item
  290. Angiotensin AT1 Receptors 1 item
  291. D4 Receptors 1 item
  292. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  293. NMDA receptor 1 item
  294. HBV Proteases 1 item
  295. Hydroxylases 2item
  296. Flk-1 1 item
  297. Papains 2item
  298. Protein Arginine Methyltransferases 1 item
  299. IMPDH 1 item
  300. Na /Ca2 Exchangers (NCXs) 1 item
  301. NAE 2item
  302. Ubiquitin-activating Enzyme E1 2item
  303. SUMOylation 1 item
  304. ATGL 1 item
  305. BACE 3item
  306. Cytidine deaminases 1 item
  307. angiogenesis 1 item
  308. Glucagon Receptors 1 item
  309. 15-PGDH 1 item
  310. DPP-4 5item
  311. c-RET 3item
  312. Nonstructural protein 5B (NS5B) 1 item
  313. p70 rsk 3item
  314. voltage-gated chloride channels 1 item
  315. FPTase 1 item
  316. Microtubule/Tubulin 1 item
  317. VEGFR3/FLT4 1 item
  318. NTRK1/TRKA 1 item
  319. CSF-1R/c-Fms 1 item
  320. Menin-MLL 2item
  321. Tryptophan hydroxylases (TPH) 2item
  322. ADAMs 1 item
  323. NMPRTase 1 item
  324. Bfl-1 1 item
  325. TAM kinase 1 item
  326. sodium channels 1 item
  327. p53-MDM2 interaction 2item
  328. nuclear export 1 item
  329. CRM1 1 item
  330. PTP 1 item
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  332. Fyn kinase 1 item
  333. Abl kinases 1 item
  334. Trypsin-like protease 1 item
  335. AXL 1 item
  336. Glyoxalase I 1 item
  337. dCTP Pyrophosphatases 1 item
  338. Protein polybromo-1 1 item
  339. SMARCA4 1 item
  340. SMARCA2 1 item
  341. ERAD 1 item
  342. Dipeptidyl-peptidase II 1 item
  343. p53 4item
  344. metalloprotease 1 item
  345. HDAC 2item
  346. KDM 2item
  347. 5-HT receptors 1 item
  348. sodium channel 3item
  349. c-Fms tyrosine kinase 1 item
  350. human lyase 1 item
  351. insulin 1 item
  352. Ub-conjugating enzyme (E2) complex 1 item
  353. Smoothened receptor 1 item
  354. quinone oxidoreductase 1 item
  355. cysteine protease 2item
  356. Nrf2/ARE signal 1 item
  357. PPAR 1 item
  358. haspin kinase 1 item
  359. STK 1 item
  360. USP1/USF1 complex 1 item
  361. IKK 1 item
  362. MSK 1 item
  363. gp120-CD4 interaction 1 item
  364. HCV polymerase 3item
  365. Ftase 1 item
  366. Subtilisin/Kex2p-like proprotein convertase 1 item
  367. PC-PLC 2item
  368. Elastases 1 item
  369. P97 ATPase 1 item
  370. NTPDases 1 item
  371. Antibiotic 1 item
  372. Mer tyrosine kinase 1 item
  373. Hec1 1 item
  374. neprilysin 1 item
  375. GLI 1 item
  376. decarboxylase 1 item
  377. HMGCR 1 item
  378. AAT 1 item
  379. ErbB-2 1 item
  380. adrenergic receptor 2item
  381. 5-HT4 Receptor 1 item
  382. sterol demethylase 1 item
  383. PDK-1 1 item
  384. GAPDH 1 item
  385. telomerase 1 item
  386. Histone Acetyltransferases (HATs) 3item
  387. complex I of the mitochondrial electron transport chain 1 item
  388. F1 Fo-ATPase 1 item
  389. Prk 1 item
  390. potassium channel 1 item
  391. calcium channel 1 item
  392. Ribonucleotide Reductases 1 item
  393. Trx 1 item
  394. Tyrosinases 1 item
  395. HSP70 1 item
  396. ICAM 1 item
  397. ITK 1 item
  398. HIF-PH 1 item
  399. NOD1 1 item
  400. NUAK 1 item
  401. Rho 1 item
  402. Ubiquitin E3 Ligases 1 item
  403. DCLK2 1 item
  404. FAAH 1 item
  405. PTK 1 item
  406. integrase 1 item
  407. L3MBTL 1 item
  408. NOS 2item
  409. MDMX 1 item
  410. TYK2 2item
  411. MUSK 1 item
  412. MAP3K 1 item
  413. GPR3 1 item
  414. Lck 1 item
  415. Adenosine Deaminases 2item
  416. mitochondrial pyruvate carrier (MPC) 1 item
  417. Thrombin Receptor 1 item
  418. prolactin secretion 1 item
  419. gonadotropin release 1 item
  420. DprE 1 item
  421. carnitine reabsorption 1 item
  422. Histamine receptors 1 item
  423. GluR 1 item
  424. 5-HT receptor 1 item
  425. dopamine receptors 1 item
  426. AMPA receptor 1 item
  427. 5-alpha Reductases 1 item
  428. Flk1 2item
  429. p21 1 item
  430. DNA Ligases 1 item
  431. Prostaglandin synthesis 1 item
  432. Protein Tyrosine Phosphatases 1 item
  433. alkaline phosphatases 1 item
  434. ATPases 1 item
  435. glutamate release 1 item
  436. PAFR 1 item
  437. Aromatases 2item
  438. DHFR 1 item
  439. GARFT 1 item
  440. PHF 1 item
  441. FGR 1 item
  442. YES 2item
  443. Fyn 2item
  444. ARG 1 item
  445. Autotaxin 1 item
  446. UCH 1 item
  447. RHA 1 item
  448. HCV NS3-4A protease 1 item
  449. TRPC channel 1 item
  450. PKD 1 item
  451. Pyruvate kinases 1 item
  452. Thioredoxin Reductases 1 item
  453. enoyl-acyl-carrier protein reductase 1 item
  454. SHIP 1 item
  455. FKBP 1 item
  456. MCL1 1 item
  457. Bcl-w 1 item
  458. glutathione peroxidase 4 1 item
  459. NADH oxidase 1 item
  460. S-adenosylhomocysteine hydrolase 1 item
  461. Rho-kinase 1 item
  462. tropomyosin receptor kinase 1 item
  463. LSD 1 item
  464. DDX3 1 item
  465. PRMT 1 item
  466. ACE 1 item
  467. GLP 1 item
  468. SK 1 item
  469. MST 1 item
  470. PPK 1 item
  471. c-Syk 1 item
  472. CDK1/CyclinB 1 item
  473. NHE 1 item
  474. IDO 2item
  475. Tph 1 item
  476. PIM1 kinase 1 item
  477. phospholipase A2 1 item
  478. reverse transcriptase 1 item
  479. epoxide hydrolase 1 item
  480. Serotonin (5-HT) reuptake 1 item
  481. Cholesterol absorption 1 item
  482. Vascular Disrupting Agents (VDA) 1 item
  483. Androgen Receptor 1 item
  484. Substance P/NK1 Receptor 1 item
  485. gp120/CD4 1 item
  486. Histone Methyltransferase 1 item
  487. ATM 2item
  488. Sirtuin 1 item
  489. NE 1 item
  490. PIKfyve 1 item
  491. Bax 1 item
  492. Glycogen Phosphorylases 1 item
  493. RGS 1 item
  494. MTH1 1 item
  495. PTEN 1 item
  496. Insulin Receptor 1 item
  497. NS3/4a Proteases 1 item
  498. Ca2 -ATPases 1 item
  499. p90 S6K 1 item
  500. Dynamins 1 item
Reported Experiments
  1. Animal Experiments 964item
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Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acne 1 item
  3. Acute Disseminated Candidiasis 1 item
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  6. Acute Myelogenous Leukemia 6item
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  8. Acute Renal Failure 1 item
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  16. B-lymphoid Malignancies 1 item
  17. Brain Injuries Studies 3item
  18. Breast Cancer 120item
  19. Cancer 545item
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  22. Castration-resistant Prostate Cancer 1 item
  23. Cervical Cancer 6item
  24. Cholangiocarcinoma 2item
  25. Chronic Lymphocytic Leukemia 8item
  26. Chronic Myeloproliferative Disorders 1 item
  27. Clear Cell Renal Cell Carcinoma 2item
  28. Cocaine-Related Disorders 2item
  29. Colon Cancer 48item
  30. Colon Carcinoma 7item
  31. Colorectal Cancer 43item
  32. Depression 2item
  33. Diabetes 8item
  34. Diffuse Large B-cell Lymphoma 1 item
  35. Dyskinesia 1 item
  36. Dyslipidemia 2item
  37. Epilepsy 4item
  38. Erectile Dysfunction 4item
  39. Friedreich's Ataxia 2item
  40. Fungal Infection 1 item
  41. Fungi 1 item
  42. Glioblastoma 32item
  43. Glioma 18item
  44. HCV 5item
  45. Heart Failure 4item
  46. Hepatic Cancer 2item
  47. Hepatitis C 4item
  48. Hepatocellular Carcinoma 7item
  49. HIV 14item
  50. HIV Infections 10item
  51. Hypercholesterolemia 3item
  52. Immunological Diseases 1 item
  53. Inflammation 1 item
  54. Inflammatory Bowel Disease 1 item
  55. Inflammatory Diseases 16item
  56. Influenza 3item
  57. Kidney Injury Studies 2item
  58. Leukemia 27item
  59. Liver Cancer 3item
  60. Lung Cancer 44item
  61. Lung Carcinoma 4item
  62. Lymphoma 31item
  63. Mantle Cell Lymphoma 2item
  64. Medulloblastoma 1 item
  65. Melanoma 35item
  66. Mixed Lineage Leukemia 3item
  67. Multiple Myeloma 24item
  68. Myelofibrosis 2item
  69. Myeloma 6item
  70. Neuroblastoma 13item
  71. Neurocognitive Disorders 1 item
  72. Neuronal Protection 1 item
  73. Non-small Cell Lung Cancer 27item
  74. Non-small Cell Lung Carcinoma 2item
  75. Obsessive-Compulsive Disorder 1 item
  76. Osteoporosis 3item
  77. Ovarian Cancer 36item
  78. Pancreatic Cancer 49item
  79. Pancreatic Carcinoma 3item
  80. Prostate Cancer 55item
  81. Psoriasis 4item
  82. Psoriasis Vulgaris 1 item
  83. Pulmonary Arterial Hypertension 2item
  84. Pulmonary Fibrosis 2item
  85. Renal Cancer 4item
  86. Renal Cell Carcinoma 8item
  87. Rheumatoid Arthritis 14item
  88. Sarcoma 1 item
  89. Schizophrenia 8item
  90. Sleep Disorders 2item
  91. Soft Tissue Sarcoma 1 item
  92. Squamous Cell Carcinoma 2item
  93. Testicular Cancer 2item
  94. Thyroid Cancer 6item
  95. Tuberculosis 1 item
  96. Type 2 Diabetes 12item