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  • Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Items 31-40 of 348

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  1. GDC-0879
    A5071 GDC-0879
     1 Citation
    Target: Raf
    Summary: B-Raf inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥16.7 mg/mL
  2. LY2228820
    A5566 LY2228820
     1 Citation
    Target: p38
    Summary: P38 MAP kinase inhibitor
      ≥30.65 mg/mL
  3. GSK1059615
    B2176 GSK1059615
    Target: PI3K|mTOR
    Summary: PI3K and mTOR inhibitor,potent and reversible
      insoluble in EtOH; insoluble in H2O; ≥8.33 mg/mL
  4. TAK-632
    A8226 TAK-632
    Target: Raf
    Summary: Pan-RAF inhibitor,potent and selective
      ≥27.75 mg/mL
  5. DMAT
    A3368 DMAT
     2 Citation
    Target: Pim|CK2|HIPK2|HIPK3
    Summary: CK2 inhibitor,potent and selective
      ≥23.85 mg/mL
  6. Trametinib (GSK1120212)
    A3018 Trametinib (GSK1120212)
     7 Citation
    Target: MEK
    Summary: MEK1 and MEK2 inhibitor, potent and selective
      insoluble in H2O; insoluble in EtOH; ≥15.38 mg/mL
  7. WP1066
    A4140 WP1066
    Target: STAT|JAK
    Summary: JAK2/STAT3 inhibitor,cell-permeable
      insoluble in H2O; ≥17.8 mg/mL
  8. PLX-4720
    A3016 PLX-4720
     1 Citation
    Target: Raf
    Summary: BRAF kinase inhibitor
      ≥20.69 mg/mL
  9. BIX 02189
    A5801 BIX 02189
    Target: MEK|ERK
    Summary: Selective MEK5 inhibitor
      ≥22.05 mg/mL
  10. Enzastaurin (LY317615)
    A1670 Enzastaurin (LY317615)
     2 Citation
    Target: PKC
    Summary: PKC beta inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥8.59 mg/mL

Items 31-40 of 348

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  1. Signaling Pathways 338item
  2. Natural Products 2item
  3. Lab Reagents 1 item
Specificity
  1. Selective 237item
  2. Non-Selective 2item
Reversibility
  1. Reversible 12item
  2. Irreversible 15item
Target
  1. Caspases 2item
  2. Cyclin-Dependent Kinases 16item
  3. Proteasome 6item
  4. Cathepsins 2item
  5. Histone Deacetylases (HDACs) 15item
  6. Akt 9item
  7. Bcl-2 7item
  8. PI3K 16item
  9. Raf 9item
  10. Aurora Kinases 14item
  11. Bcl-xl 2item
  12. CSF-1R 4item
  13. Glycoproteins 1 item
  14. p97 1 item
  15. MDM2 1 item
  16. EZH2 3item
  17. mTOR 10item
  18. Bromodomains 3item
  19. MMP 1 item
  20. Thymidine Phosphorylases 1 item
  21. Androgen Receptors 2item
  22. DT-diaphorases 1 item
  23. FLT3 10item
  24. GSK-3 3item
  25. P-glycoprotein (P-gp) 3item
  26. PLK 7item
  27. Chk 2item
  28. Eph Receptors 2item
  29. VEGFR 25item
  30. PDGFR 14item
  31. c-Kit 6item
  32. RET 2item
  33. Bromodomain-containing proteins(BRDs) 1 item
  34. Phosphodiesterases (PDEs) 3item
  35. Mcl-1 3item
  36. Thymidylate Synthase 3item
  37. p38 2item
  38. Bcr-Abl 7item
  39. MEK 5item
  40. PORCN 1 item
  41. DOT1L 1 item
  42. FGFR 7item
  43. Pim 3item
  44. Deubiquitinating enzymes (DUBs) 1 item
  45. Smoothened 1 item
  46. MET 5item
  47. Src 7item
  48. Trk Receptors 3item
  49. Aminopeptidases 1 item
  50. STAT 6item
  51. EGFR 14item
  52. ROCK 1 item
  53. Hypoxia Inducible Factors (HIFs) 1 item
  54. FAK 4item
  55. JAK 10item
  56. Syk 2item
  57. EZH1 1 item
  58. DNA-PK 3item
  59. HSP90 8item
  60. Topoisomerases 9item
  61. Cytochrome P450 (CYP450) 3item
  62. ErbB 4item
  63. DNA Methyltransferases 1 item
  64. ERK 3item
  65. HMG-CoA Reductases 1 item
  66. c-MET 5item
  67. PKC 8item
  68. Calpains 2item
  69. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  70. RAD51 1 item
  71. HER2 1 item
  72. Pyk2 2item
  73. USP 1 item
  74. 5-HT2 Receptors 1 item
  75. Insulin and Insulin-like Receptors 2item
  76. PARP 2item
  77. Pyruvate dehydrogenases (PDH) 1 item
  78. ALK 5item
  79. Sphingosine kinases (SphKs) 1 item
  80. PKG 1 item
  81. PKA 4item
  82. D1 and D5 Receptors 1 item
  83. D2 Receptors 1 item
  84. D3 Receptors 1 item
  85. MK2 1 item
  86. Angiotensin-Converting Enzymes (ACEs) 1 item
  87. Tie-2 2item
  88. RSK 1 item
  89. Autophagy 2item
  90. ATM/ATR 3item
  91. COX 2item
  92. CK2 1 item
  93. HIPK2 1 item
  94. HIPK3 1 item
  95. HIV Integrases 1 item
  96. PRAK 1 item
  97. MAPKAP-K2 1 item
  98. Guanine nucleotide exchange factors (GEFs) 1 item
  99. 20S proteasomal chymotrypsin 1 item
  100. Geranylgeranyltransferase I 1 item
  101. Farnesyltransferase 1 item
  102. Nampt 3item
  103. eIF4F 1 item
  104. Cdc42 1 item
  105. Glutaminases 2item
  106. Carbonic Anhydrases 1 item
  107. Ron 1 item
  108. BLM 1 item
  109. Aldehyde Dehydrogenases 1 item
  110. Synthases/Synthetases 1 item
  111. P110 1 item
  112. Hck 1 item
  113. Inositol-requiring enzyme 1 (IRE1) 1 item
  114. Norepinephrine transporter 1 item
  115. 5-HT Transporters 1 item
  116. Histone Demethylases 1 item
  117. MNK 1 item
  118. HIV-1 reverse transcriptase 1 item
  119. Calcium-Activated Potassium (KCa) Channels 1 item
  120. Insulin Receptors 1 item
  121. IRG-1R 1 item
  122. cAMP 1 item
  123. Sulfonylurea receptors 1 item
  124. eEF-2 1 item
  125. Cdc7 1 item
  126. CMV 1 item
  127. ZAP-70 1 item
  128. Catechol O-Methyltransferase (COMT) 1 item
  129. fibrinolysis 1 item
  130. D4 Receptors 1 item
  131. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  132. Flk-1 1 item
  133. Papains 1 item
  134. Protein Arginine Methyltransferases 1 item
  135. NAE 2item
  136. Ubiquitin-activating Enzyme E1 1 item
  137. SUMOylation 1 item
  138. BACE 1 item
  139. Cytidine deaminases 1 item
  140. angiogenesis 1 item
  141. DPP-4 1 item
  142. c-RET 2item
  143. p70 rsk 2item
  144. VEGFR3/FLT4 1 item
  145. NTRK1/TRKA 1 item
  146. CSF-1R/c-Fms 1 item
  147. NMPRTase 1 item
  148. Bfl-1 1 item
  149. TAM kinase 1 item
  150. p53-MDM2 interaction 1 item
  151. nuclear export 1 item
  152. CRM1 1 item
  153. KDR 2item
  154. AXL 1 item
  155. Glyoxalase I 1 item
  156. ERAD 1 item
  157. p53 2item
  158. HDAC 1 item
  159. human lyase 1 item
  160. insulin 1 item
  161. Ub-conjugating enzyme (E2) complex 1 item
  162. Smoothened receptor 1 item
  163. Antibiotic 1 item
  164. Hec1 1 item
  165. GLI 1 item
  166. ErbB-2 1 item
  167. PDK-1 1 item
  168. Prk 1 item
  169. Ribonucleotide Reductases 1 item
  170. Trx 1 item
  171. HSP70 1 item
  172. TYK2 1 item
  173. MUSK 1 item
  174. MAP3K 1 item
  175. Adenosine Deaminases 1 item
  176. Flk1 2item
  177. DHFR 1 item
  178. GARFT 1 item
  179. RHA 1 item
  180. MCL1 1 item
  181. Bcl-w 1 item
  182. tropomyosin receptor kinase 1 item
  183. LSD 1 item
  184. DDX3 1 item
  185. SK 1 item
  186. PPK 1 item
  187. c-Syk 1 item
  188. CDK1/CyclinB 1 item
  189. IDO 1 item
  190. PIM1 kinase 1 item
  191. phospholipase A2 1 item
  192. Substance P/NK1 Receptor 1 item
  193. Bax 1 item