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  • Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Items 41-50 of 502

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  1. Rigosertib
    B1288 Rigosertib
    Target: PI3K|PLK
    Summary: PI3K/PLK1 inhibitor
      Soluble in DMSO
  2. Dabrafenib Mesylate (GSK-2118436)
    A3347 Dabrafenib Mesylate (GSK-2118436)
    Target: Raf
    Summary: Inhibitor of BRAF(V600) mutants
      ≥30.75 mg/mL
  3. ICG 001
    A8217 ICG 001
     1 Citation
    Summary: Wnt/β-catenin pathway inhibitor
      ≥27.43 mg/mL
  4. SB202190 (FHPI)
    A1632 SB202190 (FHPI)
     5 Citation
    Target: p38
    Summary: P38 MAPK inhibitor
  5. U0126-EtOH
    A1337 U0126-EtOH
     10 Citation
    Target: MEK
    Summary: MEK1/2 inhibitor
      ≥21.33 mg/mL
  6. LY2940680
    A8651 LY2940680
    Target: Smoothened receptor
    Summary: Hedgehog/SMO antagonist,inhibits Hh signaling
  7. GDC-0879
    A5071 GDC-0879
     1 Citation
    Target: Raf
    Summary: B-Raf inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥16.7 mg/mL
  8. LY2228820
    A5566 LY2228820
     1 Citation
    Target: p38
    Summary: P38 MAP kinase inhibitor
      ≥30.65 mg/mL
  9. GSK1059615
    B2176 GSK1059615
    Target: PI3K|mTOR
    Summary: PI3K and mTOR inhibitor,potent and reversible
      insoluble in EtOH; insoluble in H2O; ≥8.33 mg/mL
  10. PD184352 (CI-1040)
    A1792 PD184352 (CI-1040)
    Target: MEK
    Summary: Selective MEK inhibitor
      ≥47.9 mg/mL

Items 41-50 of 502

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Category
  1. Signaling Pathways 492item
  2. Natural Products 2item
  3. Lab Reagents 1 item
Specificity
  1. Selective 388item
  2. Non-Selective 2item
Reversibility
  1. Reversible 24item
  2. Irreversible 19item
Target
  1. Caspases 2item
  2. Cyclin-Dependent Kinases 22item
  3. Proteasome 9item
  4. Cathepsins 2item
  5. Histone Deacetylases (HDACs) 22item
  6. Inhibitor of apoptosis proteins (IAP) 2item
  7. Akt 11item
  8. Bcl-2 7item
  9. PI3K 26item
  10. CXCR 1 item
  11. Raf 11item
  12. Aurora Kinases 16item
  13. Bcl-xl 2item
  14. CSF-1R 4item
  15. Glycoproteins 1 item
  16. p97 1 item
  17. MDM2 1 item
  18. EZH2 3item
  19. mTOR 15item
  20. Bromodomains 4item
  21. MMP 2item
  22. Thymidine Phosphorylases 1 item
  23. Androgen Receptors 3item
  24. DT-diaphorases 1 item
  25. FLT3 12item
  26. GSK-3 5item
  27. P-glycoprotein (P-gp) 5item
  28. PLK 9item
  29. Chk 5item
  30. Eph Receptors 2item
  31. VEGFR 36item
  32. PDGFR 20item
  33. c-Kit 10item
  34. RET 4item
  35. Bromodomain-containing proteins(BRDs) 1 item
  36. Phosphodiesterases (PDEs) 3item
  37. Mcl-1 5item
  38. Thymidylate Synthase 3item
  39. p38 3item
  40. JNK 1 item
  41. SGK 1 item
  42. Bcr-Abl 8item
  43. MEK 11item
  44. PORCN 1 item
  45. DOT1L 3item
  46. FGFR 13item
  47. Insulin-like growth factor receptors(IGFRs) 1 item
  48. Pim 3item
  49. Sir2-like Family Deacetylases (Sirtuins) 2item
  50. Deubiquitinating enzymes (DUBs) 2item
  51. Smoothened 4item
  52. MET 7item
  53. Src 8item
  54. Trk Receptors 5item
  55. Integrins 1 item
  56. Aminopeptidases 2item
  57. STAT 8item
  58. Microtubules/Tubulins 3item
  59. EGFR 19item
  60. Hedgehog 1 item
  61. ROCK 1 item
  62. PAK 3item
  63. Hypoxia Inducible Factors (HIFs) 2item
  64. FAK 7item
  65. BMP and Other Activin Receptors 2item
  66. JAK 12item
  67. p300 1 item
  68. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  69. Syk 4item
  70. EZH1 1 item
  71. DNA-PK 5item
  72. HSP90 12item
  73. Gutathione S-transferase 1 item
  74. Notch 1 item
  75. TNKS 1 item
  76. Topoisomerases 10item
  77. Cytochrome P450 (CYP450) 4item
  78. Ksp 1 item
  79. ErbB 5item
  80. DNA Methyltransferases 2item
  81. Survivin 1 item
  82. ERK 4item
  83. HMG-CoA Reductases 2item
  84. c-MET 7item
  85. BMI-1 1 item
  86. PKC 9item
  87. Calpains 2item
  88. Ubiquitin-specific proteases 1 item
  89. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  90. CREBBP 1 item
  91. EP300 1 item
  92. Lyn 1 item
  93. RAD51 2item
  94. HER2 2item
  95. Pyk2 3item
  96. USP 1 item
  97. 5-HT2 Receptors 1 item
  98. Insulin and Insulin-like Receptors 2item
  99. PARP 3item
  100. Pyruvate dehydrogenases (PDH) 1 item
  101. ALK 8item
  102. ROS1 2item
  103. Sphingosine kinases (SphKs) 2item
  104. Monocarboxylate transporters (MCTs) 1 item
  105. Dehydrogenase 1 item
  106. PKG 1 item
  107. PKA 4item
  108. D1 and D5 Receptors 1 item
  109. D2 Receptors 1 item
  110. D3 Receptors 1 item
  111. MELK 1 item
  112. Insulin-like growth factors (IGFs) 1 item
  113. CSF1R 1 item
  114. Bromodomain and Extra-Terminal motif (BET) 1 item
  115. MK2 1 item
  116. Angiotensin-Converting Enzymes (ACEs) 1 item
  117. Tie-2 4item
  118. RSK 2item
  119. p70 S6K 1 item
  120. Autophagy 3item
  121. ATM/ATR 4item
  122. COX 2item
  123. CK2 1 item
  124. HIPK2 1 item
  125. HIPK3 1 item
  126. HIV Integrases 1 item
  127. PRAK 1 item
  128. MAPKAP-K2 1 item
  129. Guanine nucleotide exchange factors (GEFs) 1 item
  130. 20S proteasomal chymotrypsin 1 item
  131. Geranylgeranyltransferase I 1 item
  132. Farnesyltransferase 1 item
  133. Nampt 3item
  134. eIF4F 1 item
  135. Cdc42 1 item
  136. Glutaminases 2item
  137. Carbonic Anhydrases 1 item
  138. Ron 1 item
  139. BLM 1 item
  140. Aldehyde Dehydrogenases 1 item
  141. Synthases/Synthetases 1 item
  142. P110 1 item
  143. Hck 1 item
  144. Inositol-requiring enzyme 1 (IRE1) 1 item
  145. Norepinephrine transporter 1 item
  146. 5-HT Transporters 1 item
  147. Histone Demethylases 1 item
  148. MNK 1 item
  149. HIV-1 reverse transcriptase 1 item
  150. Calcium-Activated Potassium (KCa) Channels 1 item
  151. Insulin Receptors 1 item
  152. IRG-1R 1 item
  153. cAMP 1 item
  154. Sulfonylurea receptors 1 item
  155. eEF-2 1 item
  156. Cdc7 1 item
  157. CMV 1 item
  158. ZAP-70 1 item
  159. Catechol O-Methyltransferase (COMT) 1 item
  160. fibrinolysis 1 item
  161. D4 Receptors 1 item
  162. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  163. Flk-1 1 item
  164. Papains 1 item
  165. Protein Arginine Methyltransferases 1 item
  166. NAE 2item
  167. Ubiquitin-activating Enzyme E1 1 item
  168. SUMOylation 1 item
  169. BACE 1 item
  170. Cytidine deaminases 1 item
  171. angiogenesis 1 item
  172. DPP-4 1 item
  173. c-RET 2item
  174. p70 rsk 2item
  175. VEGFR3/FLT4 1 item
  176. NTRK1/TRKA 1 item
  177. CSF-1R/c-Fms 1 item
  178. NMPRTase 1 item
  179. Bfl-1 1 item
  180. TAM kinase 1 item
  181. p53-MDM2 interaction 1 item
  182. nuclear export 1 item
  183. CRM1 1 item
  184. KDR 2item
  185. AXL 1 item
  186. Glyoxalase I 1 item
  187. ERAD 1 item
  188. p53 2item
  189. HDAC 1 item
  190. human lyase 1 item
  191. insulin 1 item
  192. Ub-conjugating enzyme (E2) complex 1 item
  193. Smoothened receptor 1 item
  194. Antibiotic 1 item
  195. Hec1 1 item
  196. GLI 1 item
  197. ErbB-2 1 item
  198. PDK-1 1 item
  199. Prk 1 item
  200. Ribonucleotide Reductases 1 item
  201. Trx 1 item
  202. HSP70 1 item
  203. TYK2 1 item
  204. MUSK 1 item
  205. MAP3K 1 item
  206. Adenosine Deaminases 1 item
  207. Flk1 2item
  208. DHFR 1 item
  209. GARFT 1 item
  210. RHA 1 item
  211. MCL1 1 item
  212. Bcl-w 1 item
  213. tropomyosin receptor kinase 1 item
  214. LSD 1 item
  215. DDX3 1 item
  216. SK 1 item
  217. PPK 1 item
  218. c-Syk 1 item
  219. CDK1/CyclinB 1 item
  220. IDO 1 item
  221. PIM1 kinase 1 item
  222. phospholipase A2 1 item
  223. Substance P/NK1 Receptor 1 item
  224. Bax 1 item