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Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Search results for: 'research area pi3k akt signaling pi3k inhibitors'

A4326 TAK-700 (Orteronel)

2 Citation

Target: human lyase

Summary: Human 17,20-lyase inhibitor

insoluble in H2O; ≥11.2 mg/mL
A8325 Tivantinib (ARQ 197)

2 Citation

Target: MET

Summary: C-Met inhibitor,non-ATP-competitive

≥18.47 mg/mL
A3820 Simeprevir

1 Citation

Target: HCV Proteases

Summary: Inhibitor of HCV NS3/4A protease

insoluble in H2O; insoluble in EtOH; ≥18.75 mg/mL
A3586 MB05032

1 Citation

Summary: GNG inhibitor,special and efficacious

Soluble in DMSO
B4890 HPOB

1 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC6 inhibitor, potent and selective

≥31.4 mg/mL
A8238 VX-765

1 Citation

Target: Caspases

Summary: Caspase-1 inhibitor,potent and selective

insoluble in H2O; ≥313 mg/mL
A3965 BI 2536

1 Citation

Target: PLK|Bromodomain-containing proteins(BRDs)

Summary: Plk1 inhibitor,potent and ATP-competitive

insoluble in H2O; ≥13.04 mg/mL
B1112 Merimepodib

Target: IMPDH

Summary: Novel noncompetitive inhibitor of IMPDH(Inosine monophosphate dehydrogenase).

≥45.2 mg/mL
A8395 CHIR-98014

Target: GSK-3

Summary: GSK-3β inhibitor,selective and ATP-competitive

insoluble in H2O; insoluble in EtOH; ≥8.1 mg/mL
A4489 TC-A 2317 hydrochloride

Target: Aurora Kinases

Summary: Aurora kinase A inhibitor,potent and selective

<39.29 mg/mL